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"I" of the Storm: Understanding the Suicidal Mind, The

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ISBNs: 9783110374827 (impreso) 9783110399226 (en línea)

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No requiere 2014 degruyter.com acceso abierto

Cobertura temática: Psicología y ciencias cognitivas - Otras ciencias sociales  

We cannot explain why people kill themselves. There are no necessary or sufficient causes for suicide, so rather than explaining suicide (looking for causes), perhaps we can understand suicide, at least in one individual, a phenomenological approach. This book begins by examining the diaries from eight individuals who killed themselves. Using qualitative analyses, supplemented in some cases by quantitative analyses, Lester seeks to uncover the unique thoughts and feelings that led these individuals to take their own lives. Lester has also studied suicide notes, the poems of those who died by suicide (both famous poets and unpublished poets), the letters written by suicides, blogs and twitter feeds, and one tape recording of a young man who killed himself just an hour or so after he recorded the tape. This book will give you insights into the “I” of the storm, the suicidal mind.

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"One rotten apple spoils the whole barrel": The plant hormone ethylene, the small molecule and its complexity

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ISBNs: 9782889196234 (impreso)

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Cobertura temática: Ciencias biológicas - Medicina básica - Otras ciencias sociales  

The gaseous molecule ethylene (C2H4), which is small in size and simple in structure, is a plant hormone most often associated with fruit ripening yet has a diversity of effects throughout the plant life cycle. While its agricultural effects were known even in ancient Egypt, the complexity of its mode of action and the broad spectrum of its effects and potential uses in plant physiology remain important scientific challenges today. In the last few decades, the biochemical pathway of ethylene production has been uncovered, ethylene perception and signaling have been molecularly dissected, ethylene-responsive transcription factors have been identified and numerous effects of ethylene have been described, ranging from water stress, development, senescence, reproduction plant-pathogen interactions, and of course, ripening. Thus ethylene is involved in plant development, in biotic and abiotic stress, and in reproduction. There is no stage in plant life that is not affected by ethylene, modulated by a complex and fascinating molecular machinery.

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"Sólo por adorno y entretenimiento": Impresores, redactores y públicos lectores en las publicaciones periódicas de entretenimiento en Buenos Aires (1837-1874)

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Autores/as: Diego Labra ; Alberto Anibal Pérez ; Claudia Román

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No requiere 2019 SEDICI: Repositorio Institucional de la UNLP (SNRD) acceso abierto
No requiere 2019 Memoria Académica (SNRD) acceso abierto

Cobertura temática: Ciencias sociales - Medios de comunicación - Otras ciencias sociales  

En esta tesis doctoral analizamos un corpus de publicaciones periódicas editadas en Buenos Aires durante las décadas centrales del siglo XIX que interpelaron a los lectores para que las leyeran, al menos en alguna medida, por entretenimiento. Esta afirmación ya presupone una hipótesis: la existencia de un conjunto de impresos que surgieron con el fin de incentivar una demanda de lectura “frívola”, “lijera”, o “divertida”, como adjetivaron los contemporáneos, que existió en simultáneo, a la sombra, de otra prensa mucho más estudiada, predominantemente diarística, que debía mostrarse preocupada por construir o por expresar una “opinión” pública, ante todo en el terreno político. De manera general, proponemos que con el semanario La Moda, en 1837 se abrió un proceso que se desarrolló al ritmo del ensayo y el error, que a lo largo de tres décadas produjo periódicos con una propuesta editorial explícitamente dirigida a la lectura por entretenimiento para el tiempo de ocio. Es decir, se fue configurado un nuevo tipo de dispositivo, mediante el despliegue de una serie de recursos discursivos, formales y materiales, asociados en ocasiones a innovaciones comerciales. Este proceso, además, contribuyó a la ampliación del lectorado, a la articulación de un mercado para la prensa, y tendió a una renegociación del “pacto de lectura” tácito entre productores y consumidores con una mirada más tolerante ante la noción de leer por entretenimiento, en contraste con la lectura erudita o con un fin pedagógico. Para dar cuenta de ese proceso, recurrimos al análisis de cinco periódicos. En una primera parte, que abarca desde 1837 hasta 1863, nos ocupamos de La Moda (1837-1838), el Diario de la Tarde (1831-1852), y los primeros ensayos por difundir recursos discursivos y formales asociados a la lectura por entretenimiento en un mercado porteño donde el éxito material de dichas iniciativas era aún imposible. La segunda parte cubre desde la aparición de los primeros periódico ilustrados exitosos como el Correo del Domingo (1864-1868) y El Mosquito (1863-1893) hasta el desenlace de una “periódico-manía” que tuvo como protagonista al Correo de las Niñas (1868-1873). Durante este decenio, desde 1863 hacia 1874, un nuevo contexto económico, social y cultural posibilitó propuestas editoriales donde la triangulación entre el folletín, la imagen impresa, y la venta de publicidad rompió con el “antiguo régimen tipográfico” porteño, insinuando una temprana “magazinización” de la prensa.

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„Dem Anwenden muss das Erkennen vorausgehen": Auf dem Weg zu einer Geschichte der Kaiser-Wilhelm-/Max-Planck-Gesellschaft

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ISBNs: 9783945561010 (impreso)

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Cobertura temática: Derecho - Otras ciencias sociales  

Anknüpfend an die Tradition der Kaiser-Wilhelm-Gesellschaft ist die Max-Planck-Gesellschaft heute eine einzigartige Institution der Grundlagenforschung, die weltweit Attraktivität und Vorbildwirkung besitzt. Auf welchen Erfahrungen und Prinzipien beruht diese Wirkung? Wie fanden die Kaiser-Wilhelm-Gesellschaft und dann die Max-Planck-Gesellschaft ihre Themen, wo wurden Durchbrüche erreicht und welche strukturellen Voraussetzungen haben erreichte Erfolge? Wie verhält sich die Dynamik der Wissenschaftsentwicklung zur gesellschaftlichen Dynamik? Wie hat sich ihr Selbstverständnis im Laufe der über hundert Jahre ihres Bestehens gewandelt? Wie finanziert sie sich? Schließen das „Harnack-Prinzip“ als institutionelles Markenzeichen und ein „Großbetrieb der Wissenschaft“ einander aus? Wie haben Kaiser-Wilhelm-Gesellschaft und Max-Planck-Gesellschaft die großen politischen Umbrüche des 20. Jahrhunderts erlebt und überlebt? Mit einer Politik der Entpolitisie-rung? Das sind Überlegungen und Fragen, denen die zwölf Autorinnen und Autoren dieses Sammelbands in ihren Beiträgen nachgehen. Sie sind hervorgegangen aus einem Kolloquium, das 2010/11 anlässlich des 100-jährigen Jubiläums der Gesellschaft im Max-Planck-Institut für Wissenschaftsgeschichte in Berlin stattfand.

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1914: Austria-Hungary, the Origins, and the First Year of World War I

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Autores/as: Samuel R. Jr. Wailliamson ; Ferdinand Karlhofer ; Günter Bischof

ISBNs: 978-1-60801-026-4 (impreso) 978-1-60801-137-7 (en línea)

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Cobertura temática: Otras ciencias sociales - Historia y arqueología - Otras humanidades  


1991 Solar World Congress

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978-0-08-041690-8 (en línea)

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No detectada 1992 ScienceDirect

Cobertura temática: Otras ciencias sociales  

The ISES Solar World Congress, held in Denver, Colorado in August 1991 attracted over 1000 participants from nearly 70 countries, making it the largest solar energy event of its kind in the world. As a lasting record of that congress, 630 papers are published here in 4 volumes of proceedings. Volume 1 is dedicated to solar energy, biofuels and renewable resources. Volume 2 contains papers on active solar and solar heat. Passive solar, socio-economic and educational aspects are considered in Volume 3, and finally the plenary sessions, and the Farrington Daniels lecture are published in Volume 4. 1991 Solar World Congress presents the very latest advances in the utilization of alternative energy resources and technology.

2011 Fukushima Nuclear Power Plant Accident, The: How and Why It Happened

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978-0-08-100118-9 (en línea)

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No detectada 2015 ScienceDirect

Cobertura temática: Ciencias de la computación e información - Ingeniería mecánica - Economía y negocios - Otras ciencias sociales  

In March 2011 the Fukushima nuclear power plant (NPP) in Japan was hit by an earthquake and subsequent tsunami which resulted in the release of significant amounts of radioactive material. The incident led to the suspension of nuclear programmes by a number of countries. This book provides a definitive account of the accident.

  • Outlines the main sequence of events of the 2011 Fukushima nuclear power plant accident, considers the responses of central and local government, and evaluates the response of the plant owner TEPCO.
  • Describes and assesses the effectiveness of the evacuation process and subsequent decontamination of the site and local area.
  • Offers recommendations for improving the safe design and operation of nuclear power plants and considers the future of the Fukushima plant and nuclear power generation in Japan.

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2014: what new directions for Alzheimer's disease?

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ISBNs: 9782889195350 (impreso)

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Cobertura temática: Medicina básica - Ciencias de la salud - Otras ciencias sociales  

According to the World Health Organization, more than 40 million people in the world are affected with dementia. To date, 60-70% of the cases of dementia are attributed to the Alzheimer's disease (AD). This neurodegenerative disorder gradually takes place over a period of at least 20 years before the onset of symptoms, which are impaired memory, apathy and depression. The characteristics of AD consist in neurofibrillary tangles (intraneuronal aggregates of hyperphosphorylated tau proteins) and senile plaques (dense extraneuronal deposits composed of amyloid ß (Aß)). The other features linked to these two core pathological hallmarks of AD are inflammation, oxidative stress, progressive synaptic and neuronal loss. In past years, some of the emerging therapeutic strategies against AD were employed to deal with the pathological hallmarks of the disease. Science teams all over the world try to restore the tau phosphorylation equilibrium. Their purpose is to interfere with the aggregation of tau and decrease its amount of proteins per se as well. Furthermore, they are trying either to stimulate the elimination processes of the aggregated tau proteins or to stop the formation of Aß peptides. This could be reached by the stimulation of the classic techniques of protein degradation such as the autophagic pathway, or by the targeted immunotherapy. In this Research Topic, we wish to summarize and review the etiology of AD and the related therapeutic opportunities for the next decades. To fully understand the precise mechanisms underlying AD, research findings, reviews, new insights and new approaches include AD and related tauopathies, tau phosphorylation balance, pharmacological compounds against AD, neuroprotection strategies and new therapeutic ways but also risk factors for AD and AD genetic information are included in this issue.

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30 years of the Comet Assay: an overview with some new insights

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ISBNs: 9782889196494 (impreso)

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Cobertura temática: Ciencias biológicas - Medicina básica - Medicina clínica - Ciencias de la salud - Otras ciencias sociales  

By means of this ‘Frontiers in Genetics’ research topic, we are celebrating 30 years of the Comet Assay. The first paper on this single-cell gel electrophoresis assay was published in 1984 by O. Ostling and K.J. Johanson (Biochem. Biophys. Res. Commun. Vol.123: 291-298). The comet assay is a versatile and sensitive method for measuring single - and double-strand breaks in DNA. By including lesion-specific enzymes in the assay, its range and sensitivity are greatly increased, but it is important to bear in mind that their specificity is not absolute. The comet assay (with and without inclusion of lesion-specific enzymes) is widely used as a biomarker assay in human population studies - primarily to measure DNA damage, but increasingly also to assess the capacity of cells for DNA repair. Ostling and Johanson (Biochem. Biophys. Res. Commun., 1984) were also the first to report experiments to measure DNA repair, by simply following the decrease of DNA damage over time after challenging cells with ionising radiation. However, this approach is time-consuming and laborious as it requires an extended period of cell culture and is therefore not ideal for biomonitoring studies, which typically require high-throughput processing of many samples. As an alternative approach, the in vitro comet-based repair assay was developed: a cell extract is incubated with a DNA substrate containing specific lesions, and DNA incisions accumulate. The in vitro comet-based repair assay has been modified and improved over the past decade: it was first devised to measure base excision repair of oxidised purines in lymphocytes (Collins et al., Mutagenesis, 2001), but has since been adapted for other lesions and thus other repair pathways, as well as being applied to tissue samples in addition to cell suspensions. Even after 30 years, the comet assay is still in a growth phase, with many new users each year. Many questions are repeatedly raised, which may seem to have self-evident answers, but clearly, it is necessary to reiterate them for the benefit of the new audience, and sometimes being forced to think again about old topics can shed new light. Different applications of the comet assay are discussed in this special issue, including: genotoxicity testing in different organisms, human biomonitoring, DNA repair studies, environmental biomonitoring and clinical studies. Furthermore, we consider and where possible answer questions, including the ones raised by Raymond Tice at the 8th International Comet Assay Workshop in Perugia (Italy 2009): What is the spectrum of DNA damage detected by the various versions of the comet assay?; What are the limitations associated with each application?; What should be done to standardize the assay for biomonitoring studies?; Can the comet assay be used to monitor changes in global methylation status?; What cell types are suitable for detecting genotoxic substances and their effects in vivo and in vitro?; Can the assay be fully automated?; and more. So this ‘Frontiers in Genetics’ research topic is written for the beginner as well as for the experienced users of the comet assay.

3C Vision: Cues, Context and Channels

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978-0-12-385220-5 (en línea)

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No detectada 2011 ScienceDirect

Cobertura temática: Ciencias de la computación e información - Ciencias químicas - Ingeniería de los materiales - Otras ciencias sociales  

The exponential explosion of images and videos concerns everybody's common life, since this media is now present everywhere and in all human activities. Scientists, artists and engineers, in any field, need to be aware of the basic mechanisms that allow them to understand how images are essentially information carriers. Images bear a strong evocative power because their perception quickly brings into mind a number of related pictorial contents of past experiences and even of abstract concepts like pleasure, attraction or aversion.

This book analyzes the visual hints, thanks to which images are generally interpreted, processed and exploited both by humans and computer programs.

  • Comprehensive introductory text
  • Introduces the reader to the large world of imagery on which many human activities are based, from politics to entertainment, from technical reports to artistic creations
  • Provides a unified framework where both biological and artificial vision are discussed through visual cues, through the role of contexts and the available multi-channels to deliver information