Catálogo de publicaciones - revistas
Nature Biotechnology
Resumen/Descripción – provisto por la editorial en inglés
Nature Biotechnology is a monthly journal covering the science and business of biotechnology. It publishes new concepts in technology/methodology of relevance to the biological, biomedical, agricultural and environmental sciences as well as covers the commercial, political, ethical, legal, and societal aspects of this research. The first function is fulfilled by the peer-reviewed research section, the second by the expository efforts in the front of the journal. We provide researchers with news about business; we provide the business community with news about research developments.Palabras clave – provistas por la editorial
No disponibles.
Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde jul. 2012 / hasta dic. 2023 | Nature.com |
Información
Tipo de recurso:
revistas
ISSN impreso
1087-0156
ISSN electrónico
1546-1696
Editor responsable
Springer Nature
País de edición
Reino Unido
Fecha de publicación
1996-
Cobertura temática
Tabla de contenidos
High-throughput measurement of the content and properties of nano-sized bioparticles with single-particle profiler
Taras Sych; Jan Schlegel; Hanna M. G. Barriga; Miina Ojansivu; Leo Hanke
; Florian Weber; R. Beklem Bostancioglu; Kariem Ezzat; Herbert Stangl; Birgit Plochberger; Jurga Laurencikiene; Samir El Andaloussi; Daniel Fürth; Molly M. Stevens; Erdinc Sezgin
<jats:title>Abstract</jats:title><jats:p>We introduce a method, single-particle profiler, that provides single-particle information on the content and biophysical properties of thousands of particles in the size range 5–200 nm. We use our single-particle profiler to measure the messenger RNA encapsulation efficiency of lipid nanoparticles, the viral binding efficiencies of different nanobodies, and the biophysical heterogeneity of liposomes, lipoproteins, exosomes and viruses.</jats:p>
Palabras clave: Biomedical Engineering; Molecular Medicine; Applied Microbiology and Biotechnology; Bioengineering; Biotechnology.
Pp. No disponible
Staple crops equipped for alkaline soils
Caitlin S. Byrt; A. Harvey Millar; Rana Munns
Palabras clave: Biomedical Engineering; Molecular Medicine; Applied Microbiology and Biotechnology; Bioengineering; Biotechnology.
Pp. No disponible
Adenine transversion editors enable precise, efficient A•T-to-C•G base editing in mammalian cells and embryos
Liang Chen; Mengjia Hong; Changming Luan; Hongyi Gao; Gaomeng Ru; Xinyuan Guo; Dujuan Zhang; Shun Zhang; Changwei Li; Jun Wu; Peyton B. Randolph; Alexander A. Sousa; Chao Qu; Yifan Zhu; Yuting Guan; Liren Wang; Mingyao Liu; Bo Feng; Gaojie Song; David R. Liu; Dali Li
Palabras clave: Biomedical Engineering; Molecular Medicine; Applied Microbiology and Biotechnology; Bioengineering; Biotechnology.
Pp. No disponible
A call for an ‘Asilomar’ for cultivated meat and seafood
Sveva Bottini; Claudia Fuoco; Nike Schiavo; Alessandro Bertero; Stefano Biressi; Luciano Conti; Cesare Gargioli
Palabras clave: Biomedical Engineering; Molecular Medicine; Applied Microbiology and Biotechnology; Bioengineering; Biotechnology.
Pp. No disponible
Breaking boundaries in whole-body imaging and disease understanding with wildDISCO
Palabras clave: Biomedical Engineering; Molecular Medicine; Applied Microbiology and Biotechnology; Bioengineering; Biotechnology.
Pp. No disponible
The global patent landscape of mRNA for diagnosis and therapy
Mengru Lyu; Jiyuan Chen; Yeheng Peng; Fang Han; Luyao Gong; Jingfei Guo; Lijuan Tian; Yuan Gao
Palabras clave: Biomedical Engineering; Molecular Medicine; Applied Microbiology and Biotechnology; Bioengineering; Biotechnology.
Pp. 1193-1199
Dissecting key regulators of transcriptome kinetics through scalable single-cell RNA profiling of pooled CRISPR screens
Zihan Xu; Andras Sziraki; Jasper Lee; Wei Zhou; Junyue Cao
<jats:title>Abstract</jats:title><jats:p>We present a combinatorial indexing method, <jats:italic>PerturbSci-Kinetics</jats:italic>, for capturing whole transcriptomes, nascent transcriptomes and single guide RNA (sgRNA) identities across hundreds of genetic perturbations at the single-cell level. Profiling a pooled CRISPR screen targeting various biological processes, we show the gene expression regulation during RNA synthesis, processing and degradation, miRNA biogenesis and mitochondrial mRNA processing, systematically decoding the genome-wide regulatory network that underlies RNA temporal dynamics at scale.</jats:p>
Palabras clave: Biomedical Engineering; Molecular Medicine; Applied Microbiology and Biotechnology; Bioengineering; Biotechnology.
Pp. No disponible
Killing tumor-associated bacteria with a liposomal antibiotic generates neoantigens that induce anti-tumor immune responses
Menglin Wang; Benoit Rousseau; Kunyu Qiu; Guannan Huang; Yu Zhang; Hang Su; Christine Le Bihan-Benjamin; Ines Khati; Oliver Artz; Michael B. Foote; Yung-Yi Cheng; Kuo-Hsiung Lee; Michael Z. Miao; Yue Sun; Philippe-Jean Bousquet; Marc Hilmi; Elise Dumas; Anne-Sophie Hamy; Fabien Reyal; Lin Lin; Paul M. Armistead; Wantong Song; Ava Vargason; Janelle C. Arthur; Yun Liu; Jianfeng Guo; Xuefei Zhou; Juliane Nguyen; Yongqun He; Jenny P.-Y. Ting; Aaron C. Anselmo; Leaf Huang
Palabras clave: Biomedical Engineering; Molecular Medicine; Applied Microbiology and Biotechnology; Bioengineering; Biotechnology.
Pp. No disponible
Single-cell lineage capture across genomic modalities with CellTag-multi reveals fate-specific gene regulatory changes
Kunal Jindal; Mohd Tayyab Adil; Naoto Yamaguchi; Xue Yang; Helen C. Wang; Kenji Kamimoto; Guillermo C. Rivera-Gonzalez; Samantha A. Morris
<jats:title>Abstract</jats:title><jats:p>Complex gene regulatory mechanisms underlie differentiation and reprogramming. Contemporary single-cell lineage-tracing (scLT) methods use expressed, heritable DNA barcodes to combine cell lineage readout with single-cell transcriptomics. However, reliance on transcriptional profiling limits adaptation to other single-cell assays. With CellTag-multi, we present an approach that enables direct capture of heritable random barcodes expressed as polyadenylated transcripts, in both single-cell RNA sequencing and single-cell Assay for Transposase Accessible Chromatin using sequencing assays, allowing for independent clonal tracking of transcriptional and epigenomic cell states. We validate CellTag-multi to characterize progenitor cell lineage priming during mouse hematopoiesis. Additionally, in direct reprogramming of fibroblasts to endoderm progenitors, we identify core regulatory programs underlying on-target and off-target fates. Furthermore, we reveal the transcription factor Zfp281 as a regulator of reprogramming outcome, biasing cells toward an off-target mesenchymal fate. Our results establish CellTag-multi as a lineage-tracing method compatible with multiple single-cell modalities and demonstrate its utility in revealing fate-specifying gene regulatory changes across diverse paradigms of differentiation and reprogramming.</jats:p>
Palabras clave: Biomedical Engineering; Molecular Medicine; Applied Microbiology and Biotechnology; Bioengineering; Biotechnology.
Pp. No disponible
From air to your plate: tech startups making food from atmospheric CO2
Claire Turrell
Palabras clave: Biomedical Engineering; Molecular Medicine; Applied Microbiology and Biotechnology; Bioengineering; Biotechnology.
Pp. No disponible