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computational fluid dynamics; bileaflet mechanical heart valve; adverse hemodynamics; transvalvular pressure gradients; turbulent shear stresses; blood damage; platelet activation; aortic valve; calcification; elastin degradation; leaflet; curvature; biomarker; early detection; porcine brain; mechanical behavior; hydration effects; Split-Hopkinson pressure bar; micromechanics; finite element analysis; collagen crimp; elastin; microstructures; force-controlled mechanical testing; the tricuspid valve; functional tricuspid regurgitation; cardiovascular imaging; mechanical characterization; in-vitro experiments; constitutive modeling; geometrical modeling; finite element modeling; isogeometric analysis (IGA); biaxial mechanical characterization; fluid-structure interactions; material anisotropy; sub-valvular components; soft tissue; liver; high-rate compression; polymeric split-Hopkinson pressure bar; pentagalloyl glucose; aneurysm; enzyme; biomechanics; aorta; biaxial mechanical testing; cardiac valves; osmotic swelling; parameter estimation; nonlinear preconditioning; gradient-based minimization; cirrus; myocardium; stiffness; viscoelastic property; anisotropy; fibrosis; the mitral valve; collagen fiber architecture; glycosaminoglycan; uniaxial mechanical testing; in-vitro flow loops; polarized spatial frequency domain imaging; tricuspid regurgitation; spatial alignment; collagen fiber reorientation; in vivo stress/strain quantification; constitutive models; soft tissues; growth and remodeling (G & R); multiscale biomechanics; patient-specific modeling