Catálogo de publicaciones - revistas

Compartir en
redes sociales


Nature

Resumen/Descripción – provisto por la editorial en inglés
Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.
Palabras clave – provistas por la editorial

No disponibles.

Disponibilidad
Institución detectada Período Navegá Descargá Solicitá
No detectada desde jul. 2012 / hasta dic. 2023 Nature.com
No detectada desde jul. 2006 / hasta ago. 2012 Ovid

Información

Tipo de recurso:

revistas

ISSN impreso

0028-0836

ISSN electrónico

1476-4687

Editor responsable

Springer Nature

País de edición

Reino Unido

Fecha de publicación

Tabla de contenidos

Could AI help you to write your next paper?

Matthew Hutson

Palabras clave: Multidisciplinary.

Pp. 192-193

APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes

Joel W. Blanchard; Leyla Anne AkayORCID; Jose Davila-VelderrainORCID; Djuna von Maydell; Hansruedi Mathys; Shawn M. DavidsonORCID; Audrey EffenbergerORCID; Chih-Yu Chen; Kristal Maner-Smith; Ihab Hajjar; Eric A. OrtlundORCID; Michael Bula; Emre Agbas; Ayesha Ng; Xueqiao Jiang; Martin Kahn; Cristina Blanco-Duque; Nicolas Lavoie; Liwang Liu; Ricardo Reyes; Yuan-Ta Lin; Tak Ko; Lea R’Bibo; William T. Ralvenius; David A. Bennett; Hugh P. Cam; Manolis KellisORCID; Li-Huei TsaiORCID

Palabras clave: Multidisciplinary.

Pp. No disponible

A spatial perspective on bacteria in tumours

Ilana LivyatanORCID; Ravid StraussmanORCID

Palabras clave: Multidisciplinary.

Pp. No disponible

Pressure to publish is ‘fuelling illegal practices in palaeontology’

Clare Watson

Palabras clave: Multidisciplinary.

Pp. No disponible

An autoimmune mechanism underlying a fatal form of heart inflammation

Palabras clave: Multidisciplinary.

Pp. No disponible

Colon tumour cell death causes mTOR dependence by paracrine P2X4 stimulation

Mark SchmittORCID; Fatih Ceteci; Jalaj Gupta; Marina Pesic; Tim W. Böttger; Adele M. Nicolas; Kilian B. Kennel; Esther Engel; Matthias Schewe; Asude Callak Kirisözü; Valentina Petrocelli; Yasamin Dabiri; Julia Varga; Mallika Ramakrishnan; Madina Karimova; Andrea AblasserORCID; Toshiro SatoORCID; Melek C. Arkan; Frederic J. de Sauvage; Florian R. GretenORCID

Palabras clave: Multidisciplinary.

Pp. No disponible

Effect of the intratumoral microbiota on spatial and cellular heterogeneity in cancer

Jorge Luis Galeano Niño; Hanrui Wu; Kaitlyn D. LaCourse; Andrew G. KempchinskyORCID; Alexander Baryiames; Brittany Barber; Neal Futran; Jeffrey Houlton; Cassie Sather; Ewa Sicinska; Alison Taylor; Samuel S. MinotORCID; Christopher D. JohnstonORCID; Susan BullmanORCID

<jats:title>Abstract</jats:title><jats:p>The tumour-associated microbiota is an intrinsic component of the tumour microenvironment across human cancer types<jats:sup>1,2</jats:sup>. Intratumoral host–microbiota studies have so far largely relied on bulk tissue analysis<jats:sup>1–3</jats:sup>, which obscures the spatial distribution and localized effect of the microbiota within tumours. Here, by applying in situ spatial-profiling technologies<jats:sup>4</jats:sup> and single-cell RNA sequencing<jats:sup>5</jats:sup> to oral squamous cell carcinoma and colorectal cancer, we reveal spatial, cellular and molecular host–microbe interactions. We adapted 10x Visium spatial transcriptomics to determine the identity and in situ location of intratumoral microbial communities within patient tissues. Using GeoMx digital spatial profiling<jats:sup>6</jats:sup>, we show that bacterial communities populate microniches that are less vascularized, highly immuno‑suppressive and associated with malignant cells with lower levels of Ki-67 as compared to bacteria-negative tumour regions. We developed a single-cell RNA-sequencing method that we name INVADEseq (invasion–adhesion-directed expression sequencing) and, by applying this to patient tumours, identify cell-associated bacteria and the host cells with which they interact, as well as uncovering alterations in transcriptional pathways that are involved in inflammation, metastasis, cell dormancy and DNA repair. Through functional studies, we show that cancer cells that are infected with bacteria invade their surrounding environment as single cells and recruit myeloid cells to bacterial regions. Collectively, our data reveal that the distribution of the microbiota within a tumour is not random; instead, it is highly organized in microniches with immune and epithelial cell functions that promote cancer progression.</jats:p>

Palabras clave: Multidisciplinary.

Pp. No disponible

Why do bat viruses keep infecting people?

Smriti Mallapaty

Palabras clave: Multidisciplinary.

Pp. No disponible

Integrated femtosecond pulse generator on thin-film lithium niobate

Mengjie Yu; David Barton III; Rebecca Cheng; Christian Reimer; Prashanta Kharel; Lingyan He; Linbo Shao; Di ZhuORCID; Yaowen HuORCID; Hannah R. Grant; Leif Johansson; Yoshitomo OkawachiORCID; Alexander L. GaetaORCID; Mian Zhang; Marko LončarORCID

Palabras clave: Multidisciplinary.

Pp. No disponible

Legal win for US scientist bolsters others caught in China crackdown

Natasha Gilbert

Palabras clave: Multidisciplinary.

Pp. No disponible