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Nature

Resumen/Descripción – provisto por la editorial en inglés
Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.
Palabras clave – provistas por la editorial

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Disponibilidad
Institución detectada Período Navegá Descargá Solicitá
No detectada desde jul. 2012 / hasta dic. 2023 Nature.com
No detectada desde jul. 2006 / hasta ago. 2012 Ovid

Información

Tipo de recurso:

revistas

ISSN impreso

0028-0836

ISSN electrónico

1476-4687

Editor responsable

Springer Nature

País de edición

Reino Unido

Fecha de publicación

Tabla de contenidos

Movement is governed by rotational neural dynamics in spinal motor networks

Henrik Lindén; Peter C. PetersenORCID; Mikkel VestergaardORCID; Rune W. BergORCID

Palabras clave: Multidisciplinary.

Pp. No disponible

New catalogue of Earth’s ecosystems

Brian J. McGill; Stephanie N. Miller

Palabras clave: Multidisciplinary.

Pp. No disponible

Global hotspots for soil nature conservation

Carlos A. GuerraORCID; Miguel BerdugoORCID; David J. EldridgeORCID; Nico EisenhauerORCID; Brajesh K. SinghORCID; Haiying Cui; Sebastian AbadesORCID; Fernando D. Alfaro; Adebola R. Bamigboye; Felipe BastidaORCID; José L. Blanco-PastorORCID; Asunción de los RíosORCID; Jorge DuránORCID; Tine GrebencORCID; Javier G. Illán; Yu-Rong LiuORCID; Thulani P. MakhalanyaneORCID; Steven MametORCID; Marco A. Molina-Montenegro; José L. MorenoORCID; Arpan Mukherjee; Tina U. Nahberger; Gabriel F. Peñaloza-BojacáORCID; César PlazaORCID; Sergio Picó; Jay Prakash VermaORCID; Ana ReyORCID; Alexandra RodríguezORCID; Leho Tedersoo; Alberto L. TeixidoORCID; Cristian Torres-Díaz; Pankaj TrivediORCID; Juntao WangORCID; Ling Wang; Jianyong WangORCID; Eli ZaadyORCID; Xiaobing Zhou; Xin-Quan Zhou; Manuel Delgado-BaquerizoORCID

Palabras clave: Multidisciplinary.

Pp. No disponible

Global soil map pinpoints key sites for conservation

Peter C. de Ruiter; Elly Morriën

Palabras clave: Multidisciplinary.

Pp. No disponible

Activation of γ-globin expression by hypoxia-inducible factor 1α

Ruopeng Feng; Thiyagaraj Mayuranathan; Peng HuangORCID; Phillip A. DoerflerORCID; Yichao LiORCID; Yu Yao; Jingjing Zhang; Lance E. PalmerORCID; Kalin Mayberry; Georgios E. Christakopoulos; Peng Xu; Chunliang LiORCID; Yong ChengORCID; Gerd A. BlobelORCID; M. Celeste SimonORCID; Mitchell J. WeissORCID

Palabras clave: Multidisciplinary.

Pp. No disponible

Spontaneous generation and active manipulation of real-space optical vortices

Dongha KimORCID; Arthur BaucourORCID; Yun-Seok Choi; Jonghwa ShinORCID; Min-Kyo SeoORCID

Palabras clave: Multidisciplinary.

Pp. No disponible

Fast charging of energy-dense lithium-ion batteries

Chao-Yang WangORCID; Teng Liu; Xiao-Guang Yang; Shanhai Ge; Nathaniel V. Stanley; Eric S. Rountree; Yongjun Leng; Brian D. McCarthyORCID

Palabras clave: Multidisciplinary.

Pp. No disponible

General-relativistic precession in a black-hole binary

Mark HannamORCID; Charlie Hoy; Jonathan E. Thompson; Stephen FairhurstORCID; Vivien Raymond; Marta Colleoni; Derek Davis; Héctor Estellés; Carl-Johan Haster; Adrian Helmling-Cornell; Sascha Husa; David Keitel; T. J. Massinger; Alexis Menéndez-Vázquez; Kentaro Mogushi; Serguei Ossokine; Ethan Payne; Geraint Pratten; Isobel Romero-Shaw; Jam Sadiq; Patricia Schmidt; Rodrigo Tenorio; Richard Udall; John Veitch; Daniel Williams; Anjali Balasaheb Yelikar; Aaron Zimmerman

Palabras clave: Multidisciplinary.

Pp. No disponible

Structure of the OMEGA nickase IsrB in complex with ωRNA and target DNA

Seiichi HiranoORCID; Kalli KappelORCID; Han Altae-Tran; Guilhem FaureORCID; Max E. WilkinsonORCID; Soumya KannanORCID; F. Esra Demircioglu; Rui Yan; Momoko Shiozaki; Zhiheng YuORCID; Kira S. MakarovaORCID; Eugene V. KooninORCID; Rhiannon K. Macrae; Feng ZhangORCID

<jats:title>Abstract</jats:title><jats:p>RNA-guided systems, such as CRISPR–Cas, combine programmable substrate recognition with enzymatic function, a combination that has been used advantageously to develop powerful molecular technologies<jats:sup>1,2</jats:sup>. Structural studies of these systems have illuminated how the RNA and protein jointly recognize and cleave their substrates, guiding rational engineering for further technology development<jats:sup>3</jats:sup>. Recent work identified a new class of RNA-guided systems, termed OMEGA, which include IscB, the likely ancestor of Cas9, and the nickase IsrB, a homologue of IscB lacking the HNH nuclease domain<jats:sup>4</jats:sup>. IsrB consists of only around 350 amino acids, but its small size is counterbalanced by a relatively large RNA guide (roughly 300-nt ωRNA). Here, we report the cryogenic-electron microscopy structure of <jats:italic>Desulfovirgula thermocuniculi</jats:italic> IsrB (DtIsrB) in complex with its cognate ωRNA and a target DNA. We find the overall structure of the IsrB protein shares a common scaffold with Cas9. In contrast to Cas9, however, which uses a recognition (REC) lobe to facilitate target selection, IsrB relies on its ωRNA, part of which forms an intricate ternary structure positioned analogously to REC. Structural analyses of IsrB and its ωRNA as well as comparisons to other RNA-guided systems highlight the functional interplay between protein and RNA, advancing our understanding of the biology and evolution of these diverse systems.</jats:p>

Palabras clave: Multidisciplinary.

Pp. No disponible

Ancient Greenlanders hunted huge whales — and little reindeer

Palabras clave: Multidisciplinary.

Pp. No disponible