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Nature

Resumen/Descripción – provisto por la editorial en inglés
Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.
Palabras clave – provistas por la editorial

No disponibles.

Disponibilidad
Institución detectada Período Navegá Descargá Solicitá
No detectada desde jul. 2012 / hasta dic. 2023 Nature.com
No detectada desde jul. 2006 / hasta ago. 2012 Ovid

Información

Tipo de recurso:

revistas

ISSN impreso

0028-0836

ISSN electrónico

1476-4687

Editor responsable

Springer Nature

País de edición

Reino Unido

Fecha de publicación

Tabla de contenidos

‘Mind-blowing’ IBM chip speeds up AI

Davide Castelvecchi

Palabras clave: Multidisciplinary.

Pp. No disponible

AI could be an opportunity for research managers

Simon Baker

Palabras clave: Multidisciplinary.

Pp. No disponible

How to rebuild trust in science: NIH director nominee fields questions

Max Kozlov

Palabras clave: Multidisciplinary.

Pp. No disponible

This fast radio burst took 8 billion years to reach Earth

Gemma Conroy

Palabras clave: Multidisciplinary.

Pp. No disponible

How paediatrician researchers are advancing child health

Nikki Forrester

Palabras clave: Multidisciplinary.

Pp. S5-S9

Carl Sagan’s audacious search for life on Earth has lessons for science today

Palabras clave: Multidisciplinary.

Pp. 432-432

Long COVID research risks losing momentum – we need a moonshot

Lisa McCorkell; Michael J. Peluso

Palabras clave: Multidisciplinary.

Pp. 457-460

Measurement-induced entanglement and teleportation on a noisy quantum processor

; J. C. HokeORCID; M. Ippoliti; E. RosenbergORCID; D. Abanin; R. Acharya; T. I. Andersen; M. Ansmann; F. Arute; K. Arya; A. Asfaw; J. Atalaya; J. C. BardinORCID; A. BengtssonORCID; G. Bortoli; A. Bourassa; J. Bovaird; L. Brill; M. Broughton; B. B. BuckleyORCID; D. A. Buell; T. Burger; B. BurkettORCID; N. Bushnell; Z. Chen; B. Chiaro; D. Chik; J. Cogan; R. Collins; P. Conner; W. Courtney; A. L. Crook; B. CurtinORCID; A. G. Dau; D. M. Debroy; A. Del Toro BarbaORCID; S. DemuraORCID; A. Di PaoloORCID; I. K. DrozdovORCID; A. Dunsworth; D. EppensORCID; C. Erickson; E. Farhi; R. Fatemi; V. S. Ferreira; L. F. Burgos; E. Forati; A. G. Fowler; B. Foxen; W. Giang; C. Gidney; D. Gilboa; M. Giustina; R. GosulaORCID; J. A. GrossORCID; S. HabeggerORCID; M. C. Hamilton; M. Hansen; M. P. HarriganORCID; S. D. HarringtonORCID; P. Heu; M. R. HoffmannORCID; S. HongORCID; T. Huang; A. Huff; W. J. HugginsORCID; S. V. Isakov; J. Iveland; E. Jeffrey; Z. JiangORCID; C. Jones; P. JuhasORCID; D. Kafri; K. Kechedzhi; T. Khattar; M. Khezri; M. Kieferová; S. Kim; A. Kitaev; P. V. Klimov; A. R. Klots; A. N. Korotkov; F. Kostritsa; J. M. Kreikebaum; D. LandhuisORCID; P. Laptev; K.-M. Lau; L. Laws; J. Lee; K. W. Lee; Y. D. Lensky; B. J. Lester; A. T. Lill; W. Liu; A. Locharla; O. Martin; J. R. McCleanORCID; M. McEwen; K. C. Miao; A. Mieszala; S. MontazeriORCID; A. MorvanORCID; R. Movassagh; W. MruczkiewiczORCID; M. NeeleyORCID; C. NeillORCID; A. Nersisyan; M. Newman; J. H. NgORCID; A. Nguyen; M. Nguyen; M. Y. Niu; T. E. O’BrienORCID; S. Omonije; A. Opremcak; A. Petukhov; R. Potter; L. P. PryadkoORCID; C. Quintana; C. Rocque; N. C. Rubin; N. Saei; D. SankORCID; K. SankaragomathiORCID; K. J. SatzingerORCID; H. F. SchurkusORCID; C. Schuster; M. J. Shearn; A. Shorter; N. ShuttyORCID; V. Shvarts; J. Skruzny; W. C. Smith; R. Somma; G. Sterling; D. Strain; M. Szalay; A. Torres; G. Vidal; B. Villalonga; C. V. HeidweillerORCID; T. White; B. W. K. WooORCID; C. Xing; Z. J. Yao; P. YehORCID; J. Yoo; G. Young; A. ZalcmanORCID; Y. Zhang; N. ZhuORCID; N. Zobrist; H. NevenORCID; R. Babbush; D. Bacon; S. BoixoORCID; J. Hilton; E. Lucero; A. MegrantORCID; J. KellyORCID; Y. Chen; V. Smelyanskiy; X. MiORCID; V. KhemaniORCID; P. RoushanORCID

<jats:title>Abstract</jats:title><jats:p>Measurement has a special role in quantum theory<jats:sup>1</jats:sup>: by collapsing the wavefunction, it can enable phenomena such as teleportation<jats:sup>2</jats:sup> and thereby alter the ‘arrow of time’ that constrains unitary evolution. When integrated in many-body dynamics, measurements can lead to emergent patterns of quantum information in space–time<jats:sup>3–10</jats:sup> that go beyond the established paradigms for characterizing phases, either in or out of equilibrium<jats:sup>11–13</jats:sup>. For present-day noisy intermediate-scale quantum (NISQ) processors<jats:sup>14</jats:sup>, the experimental realization of such physics can be problematic because of hardware limitations and the stochastic nature of quantum measurement. Here we address these experimental challenges and study measurement-induced quantum information phases on up to 70 superconducting qubits. By leveraging the interchangeability of space and time, we use a duality mapping<jats:sup>9,15–17</jats:sup> to avoid mid-circuit measurement and access different manifestations of the underlying phases, from entanglement scaling<jats:sup>3,4</jats:sup> to measurement-induced teleportation<jats:sup>18</jats:sup>. We obtain finite-sized signatures of a phase transition with a decoding protocol that correlates the experimental measurement with classical simulation data. The phases display remarkably different sensitivity to noise, and we use this disparity to turn an inherent hardware limitation into a useful diagnostic. Our work demonstrates an approach to realizing measurement-induced physics at scales that are at the limits of current NISQ processors.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 481-486

Structure and electromechanical coupling of a voltage-gated Na+/H+ exchanger

Hyunku YeoORCID; Ved MehtaORCID; Ashutosh GulatiORCID; David DrewORCID

<jats:title>Abstract</jats:title><jats:p>Voltage-sensing domains control the activation of voltage-gated ion channels, with a few exceptions<jats:sup>1</jats:sup>. One such exception is the sperm-specific Na<jats:sup>+</jats:sup>/H<jats:sup>+</jats:sup> exchanger SLC9C1, which is the only known transporter to be regulated by voltage-sensing domains<jats:sup>2–5</jats:sup>. After hyperpolarization of sperm flagella, SLC9C1 becomes active, causing pH alkalinization and CatSper Ca<jats:sup>2+</jats:sup> channel activation, which drives chemotaxis<jats:sup>2,6</jats:sup>. SLC9C1 activation is further regulated by cAMP<jats:sup>2,7</jats:sup>, which is produced by soluble adenyl cyclase (sAC). SLC9C1 is therefore an essential component of the pH–sAC–cAMP signalling pathway in metazoa<jats:sup>8,9</jats:sup>, required for sperm motility and fertilization<jats:sup>4</jats:sup>. Despite its importance, the molecular basis of SLC9C1 voltage activation is unclear. Here we report cryo-electron microscopy (cryo-EM) structures of sea urchin SLC9C1 in detergent and nanodiscs. We show that the voltage-sensing domains are positioned in an unusual configuration, sandwiching each side of the SLC9C1 homodimer. The S4 segment is very long, 90 Å in length, and connects the voltage-sensing domains to the cytoplasmic cyclic-nucleotide-binding domains. The S4 segment is in the up configuration—the inactive state of SLC9C1. Consistently, although a negatively charged cavity is accessible for Na<jats:sup>+</jats:sup> to bind to the ion-transporting domains of SLC9C1, an intracellular helix connected to S4 restricts their movement. On the basis of the differences in the cryo-EM structure of SLC9C1 in the presence of cAMP, we propose that, upon hyperpolarization, the S4 segment moves down, removing this constriction and enabling Na<jats:sup>+</jats:sup>/H<jats:sup>+</jats:sup> exchange.</jats:p>

Palabras clave: Multidisciplinary.

Pp. No disponible

TMPRSS2 is a functional receptor for human coronavirus HKU1

Nell SaundersORCID; Ignacio Fernandez; Cyril PlanchaisORCID; Vincent MichelORCID; Maaran Michael Rajah; Eduard Baquero Salazar; Jeanne Postal; Francoise PorrotORCID; Florence Guivel-Benhassine; Catherine BlancORCID; Gaëlle Chauveau-Le Friec; Augustin Martin; Ludivine Grzelak; Rischa Maya Oktavia; Annalisa Meola; Olivia Ahouzi; Hunter Hoover-Watson; Matthieu Prot; Deborah DelauneORCID; Marion Cornelissen; Martin Deijs; Véronique Meriaux; Hugo Mouquet; Etienne Simon-LorièreORCID; Lia van der HoekORCID; Pierre LafayeORCID; Felix ReyORCID; Julian BuchrieserORCID; Olivier SchwartzORCID

Palabras clave: Multidisciplinary.

Pp. No disponible