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Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas

Resumen/Descripción – provisto por la editorial en español castellano
El Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas es una revista científica dedicada a las plantas medicinales, aromáticas, económicas y a los productos naturales bioactivos.
Palabras clave – provistas por la editorial

Plant culture; Agriculture

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Información

Tipo de recurso:

revistas

ISSN electrónico

0717-7917

País de edición

Chile

Fecha de publicación

Tabla de contenidos

N/A

Palabras clave: Complementary and alternative medicine; Plant Science; Drug Discovery; Pharmacology.

Pp. No disponible

Bacopa monnieri: Historical aspects to promising pharmacological actions for the treatment of central nervous system diseases

Andreia Fuentes SantosORCID; ; Marilia Moraes Queiroz SouzaORCID; Karoline Bach PauliORCID; Gustavo Ratti da SilvaORCID; Midia Wolff MarquesORCID; Pablo Alvarez AuthORCID; Wanessa de Campos BortolucciORCID; Zilda Cristiani GazimORCID; Giani Andrea LindeORCID; Nelson Barros ColautoORCID; Evellyn Claudia Wietzikoski LovatoORCID; Francislaine Aparecida dos Reis LiveroORCID; ; ; ; ; ; ; ; ; ; ;

<jats:p>Bacopa monnieri(L.) Wettst. (Plantaginaceae), also known as Brahmi, has been used to improve cognitive processes and intellectual functions that are related to the preservation of memory. The objective of this research is to review the ethnobotanical applications, phytochemical composition, toxicity and activity of B. monnieriin the central nervous system. It reviewed articles on B. monnieriusing Google Scholar, SciELO, Science Direct, Lilacs, Medline, and PubMed. Saponins are the main compounds in extracts of B. monnieri. Pharmacological studies showed that B. monnieriimproves learning and memory and presents biological effects against Alzheimer’s disease, Parkinson’s disease, epilepsy, and schizophrenia. No preclinical acute toxicity was reported. However, gastrointestinal side effects were reported in some healthy elderly individuals. Most studies with B. monnierihave been preclinical evaluations of cellular mechanisms in the central nervous system and further translational clinical research needs to be performed to evaluate the safety and efficacy of the plant.</jats:p>

Palabras clave: Complementary and alternative medicine; Plant Science; Drug Discovery; Pharmacology.

Pp. 131-155

Essential oils of Cordia species, compounds and applications: a systematic review

Kellen Cruvinel Rodrigues AndradeORCID; ; Diegue Henrique Nascimiento MartinsORCID; Diogo de Amorim BarrosORCID; Paula Monteiro de SouzaORCID; Damaris SilveiraORCID; Yris Maria Fonseca-BazzoORCID; Perola de Oliveira MagalhaesORCID; ; ; ; ; ;

<jats:p>The purpose of this systematic review was to identify the available literature on the essential oil from species of genus Cordia. This study followed the Preferred Reporting Items for Systematic Reviews. The search was conducted on four databases: LILACS, PubMed, Science Direct, and Scopus until June 5th, 2020, with no time or language restrictions. Sixty out of the 1,333 initially gathered studies fit the inclusion criteria after the selection process. Nine species of Cordiawere reported in the selected studies, out of which 79% of the evaluated studies reported essential oil from Cordia curassavica. The essential oil extraction methods identified were hydrodistillation and steam distillation. As for biological application, antimicrobial, anti-inflammatory, larvicidal and antioxidant activities were the most reported. The main compounds reported for essential oil were β-caryophyllene, α-humulene, α-pinene, bicyclogermacrene, and sabinene. The information reported in this systematic review can contribute scientifically to the recognition of the importance of the genus Cordia.</jats:p>

Palabras clave: Complementary and alternative medicine; Plant Science; Drug Discovery; Pharmacology.

Pp. 156-175

Evidence-based anti-viral and immunomodulatory potential of Black cumin (Nigella sativaL.) in COVID-19

Muhammad RiazORCID; ; Majid Khan; Rizwan AhmadORCID; Lina Hussain AlLehaibiORCID; Najmur Rahman; Dou DeqiangORCID; ; ; ; ;

<jats:p>Currently, the whole world is facing a life-threatening novel coronavirus 2019 (COVID-19) pandemic. Natural products are well-known for their potential role against viral disease, and some anti-viral agents have been developed to combat these diseases. Herein, the authors investigated the possible effects of this Holy plant Nigella sativaL. (NS), against coronavirus, using evidence-based and mechanistic approaches to conclude the immune-boosting and alleviation of respiratory systemeffects of NS. The pharmacological studies established a prominent role in treating various respiratory, immune systems, cardiovascular, skin, and gastrointestinal disorders. Literature supported the significant anti-viral role and showed an inhibitory role for NS against MHV-A59 CoV (mouse-hepatitis virus–A59) infected Hela, i.e., HeLaCEACAM1a (HeLa-epithelial carcinoembryonic antigen-related cell adhesion molecule 1a) cell. NS is a safe herbal product or dietary supplement and could be an effective and affordable community adjuvant treatment for coronavirus in the current scenario.</jats:p>

Palabras clave: Complementary and alternative medicine; Plant Science; Drug Discovery; Pharmacology.

Pp. 176-206

Chemical composition and larvicidal activity of the essential oil of Pimenta dioica leaves

Paulo Roberto Barros GomesORCID; ; Silvio Carvalho MarinhoORCID; Gustavo Oliveira EvertonORCID; Eduardo Fonseca SilvaORCID; Maria Alves FonteneleORCID; Wellington da Silva LyraORCID; Adriana Crispim de FreitasORCID; Virlane Kelly Lima HunaldoORCID; Romicy Dermondes SouzaORCID; Hilton Costa LouzeiroORCID; Maria do Livramento de PaulaORCID; Jonas Batista ReisORCID; Andrea Vasconcelo MeloORCID; Vuctor Elias Mouchrek FilhoORCID; ; ; ; ; ; ; ; ; ; ; ; ;

<jats:p>In this study, we investigated the main constituent, the predominant class and biological activity of the essential oil extracted from the leaves of Pimenta dioica and the pattern of the major constituent against larvae in the third stage of Aedes aegypti. For this reason, we extracted the oil by hydrodistillation, identified its components by gas chromatography coupled with mass spectrometry (GC/MS) and calculated the lethal concentration (LC50) of the larvicidal activity using the Reed-Muench method. The results show that the oil consists mainly of eugenol, in which the phenylpropanoid class predominated and the lethal concentration, LC50, was 38.86 μg mL-1at a confidence level of 2.25 μg mL-1, while the eugenol standard presented LC5079.75 μg mL-1at a confidence level of 2.10 μg mL-1. Given the facts, we conclude that the oil is more active than the standard and that it has the potential to replace chemical larvicides.</jats:p>

Palabras clave: Complementary and alternative medicine; Plant Science; Drug Discovery; Pharmacology.

Pp. 207-214

Medicinal plants used in the region of Teziutlán, Puebla, Mexico

Ana Liviere Vargas-VizuetORCID; ; Carlos Alberto Lobato-TapiaORCID; J. Refugio Tobar-ReyesORCID; Marco Tulio Solano-De la CruzORCID; Armando Ybáñez MarinezORCID; Abelardo Romero FernandezORCID; ; ; ; ;

<jats:p>The objective of this work was to collect information on the curative use of plants in the municipality of Teziutlán, Puebla through semi-structured interviews. Thus, 78 plants used for medicinal purposes were identified, of which 40 are native to Mexico and 38 introduced; The value of use (UV) of each one and the Informant's Consensus Factor (FCI) of 10 categories of diseases were calculated. The five most frequently used plants are Ruta chalepensisL., Rosmarinus officinalis, Arnica montana, Loeselia mexicana(Lam.) Brandegee and Sambucus ceruleavar., Neomexicana, which underwent a chemical and pharmacological review. On the other hand, the most frequent preparations are infusion and decoction, using mainly leaves (49.34%) and flowers (19.51%). It is concluded that the inhabitants of Teziutlán have a fairly homogeneous ethnomedical knowledge, setting the standard for research on its pharmacological properties.</jats:p>

Palabras clave: Complementary and alternative medicine; Plant Science; Drug Discovery; Pharmacology.

Pp. 224-241

Inter and intra population phenotypic variability of Lippia integrifolia(Verbenaceae) and its natural situation in the west-center of Argentina

Paula C BrunettiORCID; ; Romina LeivaORCID; Ricardo ZapataORCID; Lorena E TorresORCID; Ana G ChavesORCID; H Rodolfo JulianiORCID; Marta S OjedaORCID; ; ; ; ; ;

<jats:p>The species Lippia integrifoliais an aromatic, sub-woody shrub, distributed from Northwest and Central Argentina to Bolivia. It is among the most important native aromatic species. It presents medicinal properties, some of which have been scientifically proven. As an alternative to harvesting, the process of domestication of the species was initiated. The objective of this work was to assess the phenotypic variability based on botanical-taxonomic and morpho-agronomic descriptors and the use of indicators to evaluate its natural situation in the west-center of Argentina. We worked in five wild populations, registering morphological variables, phenology, natural regeneration, herbivory and presence of diseases. L. integrifoliapresents a wide morphological variability, which can be explained with three morphological descriptors. Natural regeneration ́s rate is very low to zero, in four of the sites. The results obtained are of importance to make decisions related to the sustainable use in situ, and to begin a program of domestication of the species.</jats:p>

Palabras clave: Complementary and alternative medicine; Plant Science; Drug Discovery; Pharmacology.

Pp. 242-255

Green coffee bean extract attenuates gentamicin induced acute nephrotoxicity in rats

Amina UnisORCID; ; Amany AbdelbaryORCID;

<jats:p>Gentamicin induced acute nephrotoxicity (GIAN) is considered as one of the important causes of acute renal failure. In recent years’ great effort has been focused on the introduction of herbal medicine as a novel therapeutic agent for prevention of GIAN. Hence, the current study was designed to investigate the effect of green coffee bean extract (GCBE) on GIAN in rats. Results of the present study showed that rat groups that received oral GCBE for 7 days after induction of GIAN (by a daily intraperitoneal injection of gentamicin for 7days), reported a significant improvement in renal functions tests when compared to the GIAN model groups. Moreover, there was significant amelioration in renal oxidative stress markers (renal malondialdehyde, renal superoxide dismutase) and renal histopathological changes in the GCBE-treated groups when compared to GIAN model group. These results indicate that GCBE has a potential role in ameliorating renal damage involved in GIAN.</jats:p>

Palabras clave: Complementary and alternative medicine; Plant Science; Drug Discovery; Pharmacology.

Pp. 256-268

Bioactive phenolic compounds and organic acids in the decoction of fruits and leaves of Schinus areiraL

Liliana S Celaya; ; Ana C Molina; Maria A. Gonzalez; Walter C. Villa; Luis R Silva; Carmen I Viturro; ; ; ; ;

<jats:p>Leaf and fruit decoctions of Schinus areiraL. from northwest Argentina were investigated here. Phenolic compounds and organic acids were analyzed by HPLC. Antioxidant capacity and α-glucosidase inhibition were determined by using in vitrotests. The general toxicity was assessed against Artemia salinanauplii. Hyperoside and 3 O-caffeoylquinic acid in leaf decoctions; gallic acid and catechin in fruit decoction were the major phenolic compounds. Malic and citric acids were the main organic acid quantified in the leaf and fruit decoctions, respectively. Fruit decoction had a relatively important content of shikimic acid, precursor of Tamiflu. Leaf decoction presents a greater richness in bioactive compounds with antiradical activity against DPPH●, O2●-and ●NO radicals. S. areiraleaves and fruits had α-glucosidase inhibitory activity comparable to hyperoside and acarbose. Fruit decoction was not eco-toxic; leaf decoction showed significant eco-toxic activity and could be chosen for the search of other bioactive compounds with pharmacological activity.</jats:p>

Palabras clave: Complementary and alternative medicine; Plant Science; Drug Discovery; Pharmacology.

Pp. 343-351

Plants and intestinal parasitosis: a review on ethnopharmacological use by the Kantaruré-Batida indigenous community of Brazil

Dayvison Rhuan Vasco-dos-SantosORCID; ; Jessica Vieira dos SantosORCID; María José Gomes de AndradeORCID; Lidiane Nunes LimaORCID; Wbaneide Martins de AndradeORCID; Erika dos Santos NunesORCID; Artur Gomes Dias-LimaORCID; Marcos André Vannier-SantosORCID; ; ; ; ; ;

<jats:p>Indigenous knowledge is one of the most notable traditional sources about plants used to treat diseases. Thus, the aim of this study was to describe the botanical features and to investigate the pharmacological properties of plants used by the Kantaruré-Batida community to treat intestinal parasitosis. Botanical characterization was performed based on integrative review and on access to ‘Flora do Brasil’ platform, whereas plants’ pharmacological properties were investigated through systematic review. Among the 21 ethnospecies used, 48% were described as having activity against intestinal parasites. Although 52% had no such activity described, other properties can account for their use, that indicates that further studies are required. Therefore, this review reinforces the importance of valuing indigenous knowledge as tool to guide antiparasitic agent trials.</jats:p>

Palabras clave: Complementary and alternative medicine; Plant Science; Drug Discovery; Pharmacology.

Pp. 268-308