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Journal of Pharmaceutical and Biomedical Analysis

Resumen/Descripción – provisto por la editorial en inglés

This journal is an international medium directed towards the needs of academic, clinical, government and industrial analysis by publishing original research reports and critical reviews on pharmaceutical and biomedical analysis. It covers the interdisciplinary aspects of analysis in the pharmaceutical, biomedical and clinical sciences, including developments in analytical methodology, instrumentation, computation and interpretation. Submissions on novel applications focussing on drug purity and stability studies, pharmacokinetics, therapeutic monitoring, metabolic profiling; drug-related aspects of analytical biochemistry and forensic toxicology; quality assurance in the pharmaceutical industry are also welcome.

Studies from areas of well established and poorly selective methods, such as UV-VIS spectrophotometry (including derivative and multi-wavelength measurements), basic electroanalytical (potentiometric, polarographic and voltammetric) methods, fluorimetry, flow-injection analysis, etc. are accepted for publication in exceptional cases only, if a unique and substantial advantage over presently known systems is demonstrated. The same applies to the assay of simple drug formulations by any kind of methods and the determination of drugs in biological samples based merely on spiked samples. Drug purity/stability studies should contain information on the structure elucidation of the impurities/degradants. Papers dealing with the analytical aspects of traditional folk medicines are acceptable if the results are expected to attract the interest of readers also outside the area of origin. Bioanalytical papers (pharmacokinetic, bioequivalence, protein and DNA binding studies) are accepted if the focus is on innovative analytical methodology.

In determining the suitability of submitted articles for publication, particular scrutiny will be placed on the degree of novelty and significance of the research and the extent to which it adds to existing knowledge in pharmaceutical and biomedical analysis. In all submissions to the journal, authors must address the question of how their proposed methodology compares with previously reported methods. A substantial body of work cannot be fractionated into different shorter papers.

Audience: Analytical scientists, management in the pharmaceutical industry, clinical chemistry laboratories, academic institutions, government agencies, biochemists, microbiology specialists, pharmaceutical formulation scientists.

Palabras clave – provistas por la editorial

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Disponibilidad

Institución detectada	Período	Navegá	Descargá	Solicitá
No detectada	desde ene. 1983 / hasta dic. 2023	ScienceDirect

Información

Tipo de recurso:

revistas

ISSN impreso

0731-7085

ISSN electrónico

1873-264X

Editor responsable

Elsevier

País de edición

Países Bajos

Fecha de publicación

1983-

Cobertura temática

Medicina básica

Tabla de contenidos

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doi: 10.1016/0731-7085(91)80085-n

Fluorescence enhancement of two terpenes commonly present in essential oils

R.J. Ochocka; A. Marzec; H. Lamparczyk

Pp. 809-812

doi: 10.1016/0731-7085(91)80100-n

Resolution of several racemic 3-hydroxy-1,4-benzodiazepin-2-ones by high-performance liquid chromatography on a chiral silica-bonded stationary phase

Laureano Oliveros; Cristina Minguillon; Catherine Billaud

Pp. 925-930

doi: 10.1016/j.jpba.2005.11.019

Investigation of degradation products in a topical gel containing erythromycin and benzoyl peroxide by liquid chromatography–mass spectrometry

Erik Haghedooren; Kiran Kumar Raju Bhupathi Raju.V.S.; Pieter Dehouck; Cindy Govaerts; Ann Van Schepdael; Jos Hoogmartens; Erwin Adams

Palabras clave: Analytical Chemistry; Spectroscopy; Clinical Biochemistry; Drug Discovery; Pharmaceutical Science.

Pp. 165-175

doi: 10.1016/j.jpba.2010.03.017

Development and validation of a stability indicating capillary electrophoresis method for the determination of metformin hydrochloride in tablets

I.I. Hamdan; A.K. Bani Jaber; A.M. Abushoffa

Palabras clave: Analytical Chemistry; Spectroscopy; Clinical Biochemistry; Drug Discovery; Pharmaceutical Science.

Pp. 1254-1257

doi: 10.1016/j.jpba.2013.06.034

Intralaboratory validation of kinetic chromogenic Limulus amebocyte lysate assay for bacterial endotoxin determination in anti-bothropic serum

Fernando F. Fingola; Sheila R.G. Albertino; Shirley de M.P. Abrantes; Helena P.S. Zamith

Palabras clave: Analytical Chemistry; Spectroscopy; Clinical Biochemistry; Drug Discovery; Pharmaceutical Science.

Pp. 93-98

doi: 10.1016/j.jpba.2014.06.008

Degradation kinetics study of cabozantinib by a novel stability-indicating LC method and identification of its major degradation products by LC/TOF-MS and LC–MS/MS

Chunyong Wu; Xue Xu; Chao Feng; Yuanyuan Shi; Wenyuan Liu; Xiaoyun Zhu; Junying Zhang

Palabras clave: Analytical Chemistry; Spectroscopy; Clinical Biochemistry; Drug Discovery; Pharmaceutical Science.

Pp. 356-363

doi: 10.1016/j.jpba.2016.05.033

Medicinal cannabis: Principal cannabinoids concentration and their stability evaluated by a high performance liquid chromatography coupled to diode array and quadrupole time of flight mass spectrometry method

Cinzia Citti; Giuseppe Ciccarella; Daniela Braghiroli; Carlo Parenti; Maria Angela Vandelli; Giuseppe Cannazza

Pp. 201-209

doi: 10.1016/j.jpba.2018.11.010

NDMA impurity in valsartan and other pharmaceutical products: Analytical methods for the determination of N-nitrosamines

Maria Kristina Parr; Jan F. Joseph

Palabras clave: Analytical Chemistry; Spectroscopy; Clinical Biochemistry; Drug Discovery; Pharmaceutical Science.

Pp. 536-549