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Toxicology in Vitro

Resumen/Descripción – provisto por la editorial en inglés
Toxicology in Vitro publishes original research papers and reviews on the application and use of in vitro systems for assessing or predicting the toxic effects of chemicals and elucidating their mechanisms of action. These in vitro techniques include utilizing cell or tissue cultures, isolated cells, tissue slices, subcellular fractions, transgenic cell cultures, and cells from transgenic organisms, as well as in silico modelling. The Journal will focus on investigations that involve the development and validation of new in vitro methods, e.g. for prediction of toxic effects based on traditional and in silico modelling; on the use of methods in high-throughput toxicology and pharmacology; elucidation of mechanisms of toxic action; the application of genomics, transcriptomics and proteomics in toxicology, as well as on comparative studies that characterise the relationship between in vitro and in vivo findings. The Journal strongly encourages the submission of manuscripts that focus on the development of in vitro methods, their practical applications and regulatory use (e.g. in the areas of food components cosmetics, pharmaceuticals, pesticides, and industrial chemicals). Toxicology in Vitro discourages papers that record reporting on toxicological effects from materials, such as plant extracts or herbal medicines, that have not been chemically characterized.

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Palabras clave – provistas por la editorial

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Disponibilidad
Institución detectada Período Navegá Descargá Solicitá
No detectada desde ene. 1987 / hasta dic. 2023 ScienceDirect

Información

Tipo de recurso:

revistas

ISSN impreso

0887-2333

ISSN electrónico

1879-3177

Editor responsable

Elsevier

País de edición

Reino Unido

Fecha de publicación

Cobertura temática

medicina-basica

Medicina básica

Tabla de contenidos

doi: 10.1016/s0887-2333(99)00083-1

The acute toxicity of surfactants on fish cells, Daphnia magna and fish—A comparative study

M Sandbacka; I Christianson; B Isomaa

Pp. 61-68

doi: 10.1016/j.tiv.2007.04.010

Cytotoxicity induced in myotubes by a Lys49 phospholipase A2 homologue from the venom of the snake Bothrops asper: Evidence of rapid plasma membrane damage and a dual role for extracellular calcium

Juan Carlos Villalobos; Rodrigo Mora; Bruno Lomonte; José María Gutiérrez; Yamileth Angulo

Palabras clave: Toxicology; General Medicine.

Pp. 1382-1389

doi: 10.1016/j.tiv.2008.03.005

Cytoskeletal alterations in interphase cells of the green alga Spirogyra decimina in response to heavy metals exposure: II. The effect of aluminium, nickel and copper

Pavel Přibyl; Vladislav Cepák; Vilém Zachleder

Palabras clave: Toxicology; General Medicine.

Pp. 1160-1168