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Acta Neuropsychiatrica
Resumen/Descripción – provisto por la editorial en inglés
Acta Neuropsychiatrica is an international journal that publishes translational high-quality research papers in neuropharmacology neuropsychiatry and neuroscience. The journal provides a forum for original basic and clinical research from disciplines and research areas relevant to the pathophysiology, neurobiology, and treatment of neuropsychiatric disorders. Acta Neuropsychiatrica provides its readership with the latest perspectives from current and emerging fields of psychiatry, neurology, pharmacology, genetics and neuroimaging. Such research may derive from the full spectrum of biological and psychological fields of inquiry encompassing classical and novel techniques/strategies. Emphasis will be given to translational original research that is of wide interest and clearly advances the field.Acta Neuropsychiatrica welcomes Full-length Original Research Articles, Short Communications, Perspectives, as well as Review Articles. Debate is encouraged in the form of Letters to the Editor. All articles published in Acta Neuropsychiatrica undergo peer review.Palabras clave – provistas por la editorial
neuropsychiatry; neurology; psychiatry; mental disorders
Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde ene. 1997 / hasta dic. 2010 | Wiley Online Library |
Información
Tipo de recurso:
revistas
ISSN impreso
0924-2708
ISSN electrónico
1601-5215
Editor responsable
John Wiley & Sons, Inc. (WILEY)
País de edición
Estados Unidos
Fecha de publicación
1989-2012
Cobertura temática
Tabla de contenidos
doi: 10.1017/neu.2022.7
Relationships between the Fear of COVID-19 Scale and regional brain atrophy in mild cognitive impairment
Takumi Takahashi
; Miho Ota; Yuriko Numata; Ayako Kitabatake; Kiyotaka Nemoto; Masashi Tamura; Masayuki Ide; Asaki Matsuzaki; Yuko Kaneda; Tetsuaki Arai
<jats:title>Abstract</jats:title><jats:sec id="S0924270822000072_as1"><jats:title>Background:</jats:title><jats:p>Several studies have reported that the pandemic of coronavirus disease 2019 (COVID-19) influenced cognitive function in the elderly. However, the effect of COVID-19-related fear on brain atrophy has not been evaluated. In this study, we evaluated the relation between brain atrophy and the effect of COVID-19-related fear by analysing changes in brain volume over time using magnetic resonance imaging (MRI).</jats:p></jats:sec><jats:sec id="S0924270822000072_as2"><jats:title>Methods:</jats:title><jats:p>Participants were 25 Japanese patients with mild cognitive impairment (MCI) or subjective cognitive decline (SCD), who underwent 1.5-tesla MRI scan twice, once before and once after the pandemic outbreak of COVID-19, and the Fear of Coronavirus Disease 2019 Scale (FCV-19S) assessment during that period. We computed regional brain atrophy per day between the 1st and 2nd scan, and evaluated the relation between the FCV-19S scores and regional shrinkage.</jats:p></jats:sec><jats:sec id="S0924270822000072_as3"><jats:title>Results:</jats:title><jats:p>There was significant positive correlation between the total FCV-19S score and volume reduction per day in the right posterior cingulate cortex. Regarding the subscales of FCV-19S, we found significant positive correlation between factor 2 of the FCV-19S and shrinkage of the right posterior cingulate cortex.</jats:p></jats:sec><jats:sec id="S0924270822000072_as4"><jats:title>Conclusions:</jats:title><jats:p>There was positive correlation between the FCV-19S score and regional brain atrophy per day. Although it is already known that the psychological effects surrounding the COVID-19 pandemic cause cognitive function decline, our results further suggest that anxiety and fear related to COVID-19 cause regional brain atrophy.</jats:p></jats:sec>
Palabras clave: Biological Psychiatry; Psychiatry and Mental health.
Pp. 153-162