Catálogo de publicaciones - revistas
Science
Resumen/Descripción – provisto por la editorial
No disponible.
Palabras clave – provistas por la editorial
No disponibles.
Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde mar. 1997 / hasta dic. 2023 | Science Journals |
Información
Tipo de recurso:
revistas
ISSN impreso
0036-8075
ISSN electrónico
1095-9203
Editor responsable
American Association for the Advancement of Science (AAAS)
País de edición
Estados Unidos
Fecha de publicación
1880-
Cobertura temática
Tabla de contenidos
Inclusion in human–machine interactions
Tahira Reid; James Gibert
<jats:p>Human–machine interactions research should include diverse subjects and benefit all people</jats:p>
Palabras clave: Multidisciplinary.
Pp. 149-150
An antiquated language, reimagined Kingdom of Characters: The Language Revolution That Made China Modern Jing Tsu Riverhead Books, 2022. 336 pp.
Zuoyue Wang
<jats:p>A new tome traces efforts to unify, reform, and modernize the Chinese language</jats:p>
Palabras clave: Multidisciplinary.
Pp. 151-151
Who gets counted and how Queer Data: Using Gender, Sex and Sexuality Data for Action Kevin Guyan Bloomsbury Academic, 2022. 240 pp.
Nancy Bates
<jats:p>Sexual orientation and gender identity data must be collected and used with thought and with care</jats:p>
Palabras clave: Multidisciplinary.
Pp. 152-152
Pakistan’s markhor population in decline
Shahid Ahmad; Ghulam Nabi
Palabras clave: Multidisciplinary.
Pp. 153-153
Central nervous system weapons dealt a blow
Michael Crowley; Malcolm Dando
Palabras clave: Multidisciplinary.
Pp. 153-154
Transboundary conservation’s rise
Jiajia Liu; Tiantian Zhang; Luke Gibson
Palabras clave: Multidisciplinary.
Pp. 154-154
In Science Journals
Michael Funk (eds.)
<jats:p> Highlights from the <jats:italic>Science</jats:italic> family of journals </jats:p>
Palabras clave: Multidisciplinary.
Pp. 155-157
In Other Journals
Caroline Ash; Jesse Smith (eds.)
<jats:p>Editors’ selections from the current scientific literature</jats:p>
Palabras clave: Multidisciplinary.
Pp. 156-157
4′-Fluorouridine is an oral antiviral that blocks respiratory syncytial virus and SARS-CoV-2 replication
Julien Sourimant
; Carolin M. Lieber; Megha Aggarwal; Robert M. Cox; Josef D. Wolf; Jeong-Joong Yoon; Mart Toots; Chengin Ye; Zachary Sticher; Alexander A. Kolykhalov; Luis Martinez-Sobrido; Gregory R. Bluemling; Michael G. Natchus; George R. Painter; Richard K. Plemper
<jats:title>Preparing antiviral defenses</jats:title> <jats:p> Antiviral drugs are an important tool in the battle against COVID-19. Both remdesivir and molnupiravir, which target the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase, were first developed against other RNA viruses. This highlights the importance of broad-spectrum antivirals that can be rapidly deployed against related emerging pathogens. Sourimant <jats:italic>et al</jats:italic> . used respiratory syncytial virus (RSV) as a primary indication in identifying further drugs that target the polymerase enzyme of RNA viruses. The authors explored derivatives of molnupiravir and identified 4′ fluorouridine (EIDD-2749) as an inhibitor of the polymerase of RSV and SARS-CoV-2. This drug can be delivered orally and was effective against RSV in mice and SARS-CoV-2 in ferrets. —VV </jats:p>
Palabras clave: Multidisciplinary.
Pp. 161-167
Cryo-EM structures of amyloid-β 42 filaments from human brains
Yang Yang; Diana Arseni; Wenjuan Zhang; Melissa Huang; Sofia Lövestam; Manuel Schweighauser; Abhay Kotecha; Alexey G. Murzin; Sew Y. Peak-Chew; Jennifer Macdonald; Isabelle Lavenir; Holly J. Garringer; Ellen Gelpi; Kathy L. Newell; Gabor G. Kovacs; Ruben Vidal; Bernardino Ghetti; Benjamin Ryskeldi-Falcon; Sjors H. W. Scheres; Michel Goedert
<jats:title>Hi-res view of human Aβ42 filaments</jats:title> <jats:p> Alzheimer’s disease is characterized by a loss of memory and other cognitive functions and the filamentous assembly of Aβ and tau in the brain. The assembly of Aβ peptides into filaments that end at residue 42 is a central event. Yang <jats:italic>et al</jats:italic> . used electron cryo–electron microscopy to determine the structures of Aβ42 filaments from human brain (see the Perspective by Willem and Fändrich). They identified two types of related S-shaped filaments, each consisting of two identical protofilaments. These structures will inform the development of better in vitro and animal models, inhibitors of Aβ42 assembly, and imaging agents with increased specificity and sensitivity. —SMH </jats:p>
Palabras clave: Multidisciplinary.
Pp. 167-172