Catálogo de publicaciones - revistas

<jats:title>Getting more from Moire</jats:title> <jats:p> Moire superlattices of twisted two-dimensional materials have emerged as a new paradigm for exploring strongly correlated electron systems. Once fabricated, however, the electronic correlations and the subsequent behavior of any device structure tend to be fixed. Schwartz <jats:italic>et al</jats:italic> . show that further sandwiching of the bilayer heterostructures between graphene electrical gates can provide a route to controlling the electronic properties in each layer separately and the electronic interaction strengths overall. The fine control of the electronic interactions, in terms of a tunable Feshbach resonance, provides a platform to explore many-body physics and quantum simulation. —ISO </jats:p>

<jats:title>Control by RNA polymerase II</jats:title> <jats:p> Evidence indicates that yeast cells initiate DNA synthesis and transition from the G <jats:sub>1</jats:sub> to the S phase of the cell cycle when cyclin 3 accumulates and causes phosphorylation of Whi5, a functional equivalent of the mammalian Rb (retinoblastoma) protein. Kõivomägi <jats:italic>et al</jats:italic> . now present evidence for a different cyclin-dependent kinase target (see the Perspective by Fisher). They found that the cyclin 3–cyclin-dependent kinase (Cdk) 1 complex in yeast promoted phosphorylation of RNA polymerase II and thus increased transcription at genes that control entry into the cell cycle. Cdks that regulate the cell cycle can thus act by similar mechanisms to so-called “transcriptional Cdks,” which are known to act as transcriptional regulators but not to function in control of cell division. —LBR </jats:p>

<jats:title>Making cardiac valves via mechanical forces</jats:title> <jats:p> Cardiac valves form in response to mechanical forces generated by the beating heart. Fukui <jats:italic>et al</jats:italic> . studied how patterning signals are generated in response to these forces (see the Perspective by Jain and Epstein). They show that two mechanotransduction pathways act in parallel to instruct cardiac valve progenitors: a well-established transient receptor potential mechanosensation pathway and an extracellular ATP-dependent purinergic receptor pathway that triggers Ca <jats:sup>2+</jats:sup> oscillations and results in nuclear translocation of the protein nuclear factor of activated T cells 1. These two synergistic mechanotransduction pathways generate positional information and control valve formation. The use of multiple pathways may be a general mechanism used by mechanosensitive biological systems to increase the robustness and precision of mechanotransduction. —BAP </jats:p>

<jats:title>Muscle repair without stem cells</jats:title> <jats:p> Skeletal muscle is a mechanical organ that endures cellular damage after contraction. Lesions caused by external injury can be repaired by muscle stem cells, which fuse with injured cells or create entirely new myofibers. Roman <jats:italic>et al</jats:italic> . describe a cell-autonomous repair process that is independent of muscle stem cells (see the Perspective by McNally and Demonbreun). After localized damage, myonuclei migrate to injury sites and locally deliver messenger RNA for cellular reconstruction. This myofiber self-repair represents a model for understanding the restoration of muscle architecture in health and disease. —BAP </jats:p>

<jats:p>A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.</jats:p>

<jats:title>The impacts of marine heatwaves</jats:title> <jats:p> Extreme warming events in the world’s oceans are becoming more widespread and frequent; 8 of the 10 most severe recorded events have taken place in the past decade. Smith <jats:italic>et al</jats:italic> . review how these marine heatwaves are severely altering ecosystem service provision, with widespread socioeconomic impacts. Heatwave effects, including range shifts and mass mortality of marine species and harmful algal blooms, have knock-on economic consequences that already run into billions of US dollars. As well as reviewing the impacts of these events, the authors discuss the mitigation and adaptation measures that are needed to alleviate the risks and damaging impacts. —AMS </jats:p>

<jats:title>Exploiting light with a twist</jats:title> <jats:p> Light possesses several degrees of freedom that can be exploited to encode information. In addition to wavelength, amplitude, phase, polarization, and pulse length, light can also be structured into vortices. These vortices carry optical angular momentum, effectively opening up many other modes as communication channels. Ni <jats:italic>et al</jats:italic> . review advances made in the nanophotonic platform where optical vortices can be generated and detected on-chip. These developments are expected to find application in classical and quantum information processing. —ISO </jats:p>