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Institución detectada Período Navegá Descargá Solicitá
No detectada desde mar. 1997 / hasta dic. 2023 Science Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0036-8075

ISSN electrónico

1095-9203

Editor responsable

American Association for the Advancement of Science (AAAS)

País de edición

Estados Unidos

Fecha de publicación

Cobertura temática

Tabla de contenidos

Levitodynamics: Levitation and control of microscopic objects in vacuum

C. Gonzalez-BallesteroORCID; M. AspelmeyerORCID; L. NovotnyORCID; R. QuidantORCID; O. Romero-IsartORCID

<jats:title>To have to hold</jats:title> <jats:p> The ability to control and cool the motion of levitated systems—in some cases down to their motional ground state—and to couple these systems to external forces provides opportunities for fundamental science and technology. Gonzalez-Ballestero <jats:italic>et al</jats:italic> . provide an overview of the status, challenges, and prospects of levitodynamics, the multidisciplinary research area that focuses on the understanding and control of optical trapping of microparticles and nanoparticles in vacuum, with the goal of eventually using such levitated particles as ultrasensitive probes for sensing applications. —ISO </jats:p>

Palabras clave: Multidisciplinary.

Pp. No disponible

Cross-reactive CD4 + T cells enhance SARS-CoV-2 immune responses upon infection and vaccination

Lucie LoyalORCID; Julian BraunORCID; Larissa HenzeORCID; Beate Kruse; Manuela DingeldeyORCID; Ulf ReimerORCID; Florian KernORCID; Tatjana SchwarzORCID; Maike MangoldORCID; Clara UngerORCID; Friederike Dörfler; Shirin KadlerORCID; Jennifer Rosowski; Kübrah Gürcan; Zehra Uyar-AydinORCID; Marco Frentsch; Florian KurthORCID; Karsten SchnatbaumORCID; Maren EckeyORCID; Stefan HippenstielORCID; Andreas HockeORCID; Marcel A. MüllerORCID; Birgit SawitzkiORCID; Stefan Miltenyi; Friedemann PaulORCID; Marcus A. MallORCID; Holger Wenschuh; Sebastian VoigtORCID; Christian DrostenORCID; Roland Lauster; Nils LachmanORCID; Leif-Erik SanderORCID; Victor M. CormanORCID; Jobst RöhmelORCID; Lil Meyer-ArndtORCID; Andreas ThielORCID; Claudia Giesecke-ThielORCID

<jats:title>Cross-reactive T cells aid in the fight</jats:title> <jats:p> There is mounting evidence that immunological memory after infection with seasonal human coronaviruses (hCoVs) contributes to cross-protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Loyal <jats:italic>et al</jats:italic> . identified a universal immunodominant coronavirus peptide found within the fusion peptide domain of coronavirus spike protein. This peptide is recognized by CD4 <jats:sup>+</jats:sup> T cells in 20% of unexposed individuals, more than 50% of SARS-CoV-2 convalescents, and 97% of subjects treated with the Pfizer–BioNTech COVID-19 vaccine. Although ubiquitous, these coronavirus-reactive T cells decreased with age, which may explain in part the increased susceptibility of elderly people to COVID-19. —STS </jats:p>

Palabras clave: Multidisciplinary.

Pp. No disponible

Reconstitution of an intact clock reveals mechanisms of circadian timekeeping

Archana G. ChavanORCID; Jeffrey A. SwanORCID; Joel HeislerORCID; Cigdem SancarORCID; Dustin C. ErnstORCID; Mingxu FangORCID; Joseph G. Palacios; Rebecca K. SpanglerORCID; Clive R. BagshawORCID; Sarvind TripathiORCID; Priya CrosbyORCID; Susan S. GoldenORCID; Carrie L. PartchORCID; Andy LiWangORCID

<jats:title>A biological clock in a test tube</jats:title> <jats:p> The biological clock of cyanobacteria, which remarkably requires just three proteins, has been reconstituted in vitro in a system that allows detailed study of its inputs and outputs, bringing new understanding of how environmental signals can influence a biological oscillator and how the clock controls cellular events such as gene transcription. Chavan <jats:italic>et al</jats:italic> . extended the known in vitro function of the core clock components to include output signals to transcriptional regulation and allow monitoring through fluorescence measurements in real time. The authors combined crystallography, mutagenesis, and quantitative modeling to further explore the clock mechanism, which may enable future synthetic biology applications. —LBR </jats:p>

Palabras clave: Multidisciplinary.

Pp. No disponible

A Decade for restoring Earth

Bernardo B. N. Strassburg

<jats:p>Next week, the United Nations Biodiversity Conference (COP 15) convenes in Kunming, China, to discuss a new global plan to conserve nature and improve the sharing of its benefits across humankind. If such a plan is successfully implemented, it will mark a turning point in the millennia-long decline of the natural world due to human activity. This prospect has been boosted by the United Nations General Assembly decision to declare 2021–2030 as the Decade of Ecosystem Restoration (the “Decade”), which aims to prevent, halt, and reverse the degradation of ecosystems across the planet.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 125-125

News at a glance

Jeffrey Brainard (eds.)

Palabras clave: Multidisciplinary.

Pp. 132-134

Pandemic enters transition phase—but to what?

Kai Kupferschmidt

<jats:p>High vaccination rates in some countries may soon make COVID-19 an “endemic” disease</jats:p>

Palabras clave: Multidisciplinary.

Pp. 135-136

Asteroid tour could reveal Solar System’s chaotic origin

Paul Voosen

<jats:p>NASA’s Lucy mission will survey Jupiter’s Trojans, thought to have been swept up by migrating gas giants</jats:p>

Palabras clave: Multidisciplinary.

Pp. 136-137

Stepping down, NIH director says it’s time for ‘new vision’

Jocelyn Kaiser

<jats:p>Navigating rough political waters and a pandemic, Francis Collins greatly expanded biomedical research agency</jats:p>

Palabras clave: Multidisciplinary.

Pp. 138-138

Megastudy yields brain cell inventory

Kelly Servick

<jats:p>Census of motor cortex aims to standardize definitions of cell types</jats:p>

Palabras clave: Multidisciplinary.

Pp. 139-139

Plan aims to slash toll from bacterial meningitis

Leslie Roberts

<jats:p>New five-in-one vaccine could help end epidemics in Africa and cut deaths worldwide by 70%, WHO says</jats:p>

Palabras clave: Multidisciplinary.

Pp. 140-141