Catálogo de publicaciones - revistas
Nature
Resumen/Descripción – provisto por la editorial en inglés
Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.Palabras clave – provistas por la editorial
No disponibles.
Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde jul. 2012 / hasta dic. 2023 | Nature.com | ||
| No detectada | desde jul. 2006 / hasta ago. 2012 | Ovid |
Información
Tipo de recurso:
revistas
ISSN impreso
0028-0836
ISSN electrónico
1476-4687
Editor responsable
Springer Nature
País de edición
Reino Unido
Fecha de publicación
1869-
Tabla de contenidos
High-brightness all-polymer stretchable LED with charge-trapping dilution
Zhitao Zhang; Weichen Wang
; Yuanwen Jiang; Yi-Xuan Wang; Yilei Wu; Jian-Cheng Lai; Simiao Niu; Chengyi Xu; Chien-Chung Shih; Cheng Wang; Hongping Yan; Luke Galuska; Nathaniel Prine; Hung-Chin Wu; Donglai Zhong; Gan Chen; Naoji Matsuhisa; Yu Zheng; Zhiao Yu; Yang Wang; Reinhold Dauskardt; Xiaodan Gu; Jeffrey B.-H. Tok; Zhenan Bao
Palabras clave: Multidisciplinary.
Pp. 624-630
Metastable hexagonal close-packed palladium hydride in liquid cell TEM
Jaeyoung Hong; Jee-Hwan Bae; Hyesung Jo; Hee-Young Park; Sehyun Lee; Sung Jun Hong; Hoje Chun; Min Kyung Cho; Juyoung Kim; Joodeok Kim; Yongju Son; Haneul Jin; Jin-Yoo Suh; Sung-Chul Kim; Ha-Kyung Roh; Kyu Hyoung Lee; Hyung-Seok Kim; Kyung Yoon Chung; Chang Won Yoon; Kiryeong Lee; Seo Hee Kim; Jae-Pyoung Ahn; Hionsuck Baik; Gyeung Ho Kim; Byungchan Han; Sungho Jin; Taeghwan Hyeon; Jungwon Park; Chang Yun Son; Yongsoo Yang; Young-Su Lee; Sung Jong Yoo; Dong Won Chun
Palabras clave: Multidisciplinary.
Pp. 631-636
Boron clusters as broadband membrane carriers
Andrea Barba-Bon; Giulia Salluce; Irene Lostalé-Seijo; Khaleel. I. Assaf; Andreas Hennig; Javier Montenegro; Werner M. Nau
<jats:title>Abstract</jats:title><jats:p>The membrane translocation of hydrophilic substances constitutes a challenge for their application as therapeutic compounds and labelling probes<jats:sup>1–4</jats:sup>. To remedy this, charged amphiphilic molecules have been classically used as carriers<jats:sup>3,5</jats:sup>. However, such amphiphilic carriers may cause aggregation and non-specific membrane lysis<jats:sup>6,7</jats:sup>. Here we show that globular dodecaborate clusters, and prominently B<jats:sub>12</jats:sub>Br<jats:sub>12</jats:sub><jats:sup>2−</jats:sup>, can function as anionic inorganic membrane carriers for a broad range of hydrophilic cargo molecules (with molecular mass of 146–4,500 Da). We show that cationic and neutral peptides, amino acids, neurotransmitters, vitamins, antibiotics and drugs can be carried across liposomal membranes. Mechanistic transport studies reveal that the carrier activity is related to the superchaotropic nature of these cluster anions<jats:sup>8–12</jats:sup>. We demonstrate that B<jats:sub>12</jats:sub>Br<jats:sub>12</jats:sub><jats:sup>2−</jats:sup> affects cytosolic uptake of different small bioactive molecules, including the antineoplastic monomethyl auristatin F, the proteolysis targeting chimera dBET1 and the phalloidin toxin, which has been successfully delivered in living cells for cytoskeleton labelling. We anticipate the broad and distinct delivery spectrum of our superchaotropic carriers to be the starting point of conceptually distinct cell-biological, neurobiological, physiological and pharmaceutical studies.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 637-642
Geophysical imaging of the Yellowstone hydrothermal plumbing system
Carol A. Finn; Paul A. Bedrosian; W. Steven Holbrook; Esben Auken; Benjamin R. Bloss; Jade Crosbie
Palabras clave: Multidisciplinary.
Pp. 643-647
Birds can transition between stable and unstable states via wing morphing
C. Harvey; V. B. Baliga; J. C. M. Wong; D. L. Altshuler; D. J. Inman
<jats:title>Abstract</jats:title><jats:p>Birds morph their wing shape to accomplish extraordinary manoeuvres<jats:sup>1–4</jats:sup>, which are governed by avian-specific equations of motion. Solving these equations requires information about a bird’s aerodynamic and inertial characteristics<jats:sup>5</jats:sup>. Avian flight research to date has focused on resolving aerodynamic features, whereas inertial properties including centre of gravity and moment of inertia are seldom addressed. Here we use an analytical method to determine the inertial characteristics of 22 species across the full range of elbow and wrist flexion and extension. We find that wing morphing allows birds to substantially change their roll and yaw inertia but has a minimal effect on the position of the centre of gravity. With the addition of inertial characteristics, we derived a novel metric of pitch agility and estimated the static pitch stability, revealing that the agility and static margin ranges are reduced as body mass increases. These results provide quantitative evidence that evolution selects for both stable and unstable flight, in contrast to the prevailing narrative that birds are evolving away from stability<jats:sup>6</jats:sup>. This comprehensive analysis of avian inertial characteristics provides the key features required to establish a theoretical model of avian manoeuvrability.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 648-653
Frontal neurons driving competitive behaviour and ecology of social groups
S. William Li; Omer Zeliger; Leah Strahs; Raymundo Báez-Mendoza; Lance M. Johnson; Aidan McDonald Wojciechowski; Ziv M. Williams
Palabras clave: Multidisciplinary.
Pp. 661-666
Cortical ensembles orchestrate social competition through hypothalamic outputs
Nancy Padilla-Coreano; Kanha Batra; Makenzie Patarino; Zexin Chen; Rachel R. Rock; Ruihan Zhang; Sébastien B. Hausmann; Javier C. Weddington; Reesha Patel; Yu E. Zhang; Hao-Shu Fang; Srishti Mishra; Deryn O. LeDuke; Jasmin Revanna; Hao Li; Matilde Borio; Rachelle Pamintuan; Aneesh Bal; Laurel R. Keyes; Avraham Libster; Romy Wichmann; Fergil Mills; Felix H. Taschbach; Gillian A. Matthews; James P. Curley; Ila R. Fiete; Cewu Lu; Kay M. Tye
Palabras clave: Multidisciplinary.
Pp. 667-671
Immune regulation by fungal strain diversity in inflammatory bowel disease
Xin V. Li; Irina Leonardi; Gregory G. Putzel; Alexa Semon; William D. Fiers; Takato Kusakabe; Woan-Yu Lin; Iris H. Gao; Itai Doron; Alejandra Gutierrez-Guerrero; Meghan B. DeCelie; Guilhermina M. Carriche; Marissa Mesko; Chen Yang; Julian R. Naglik; Bernhard Hube; Ellen J. Scherl; Iliyan D. Iliev
Palabras clave: Multidisciplinary.
Pp. 672-678
Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa
Raquel Viana; Sikhulile Moyo; Daniel G. Amoako; Houriiyah Tegally; Cathrine Scheepers; Christian L. Althaus; Ugochukwu J. Anyaneji; Phillip A. Bester; Maciej F. Boni; Mohammed Chand; Wonderful T. Choga; Rachel Colquhoun; Michaela Davids; Koen Deforche; Deelan Doolabh; Louis du Plessis; Susan Engelbrecht; Josie Everatt; Jennifer Giandhari; Marta Giovanetti; Diana Hardie; Verity Hill; Nei-Yuan Hsiao; Arash Iranzadeh; Arshad Ismail; Charity Joseph; Rageema Joseph; Legodile Koopile; Sergei L. Kosakovsky Pond; Moritz U. G. Kraemer; Lesego Kuate-Lere; Oluwakemi Laguda-Akingba; Onalethatha Lesetedi-Mafoko; Richard J. Lessells; Shahin Lockman; Alexander G. Lucaci; Arisha Maharaj; Boitshoko Mahlangu; Tongai Maponga; Kamela Mahlakwane; Zinhle Makatini; Gert Marais; Dorcas Maruapula; Kereng Masupu; Mogomotsi Matshaba; Simnikiwe Mayaphi; Nokuzola Mbhele; Mpaphi B. Mbulawa; Adriano Mendes; Koleka Mlisana; Anele Mnguni; Thabo Mohale; Monika Moir; Kgomotso Moruisi; Mosepele Mosepele; Gerald Motsatsi; Modisa S. Motswaledi; Thongbotho Mphoyakgosi; Nokukhanya Msomi; Peter N. Mwangi; Yeshnee Naidoo; Noxolo Ntuli; Martin Nyaga; Lucier Olubayo; Sureshnee Pillay; Botshelo Radibe; Yajna Ramphal; Upasana Ramphal; James E. San; Lesley Scott; Roger Shapiro; Lavanya Singh; Pamela Smith-Lawrence; Wendy Stevens; Amy Strydom; Kathleen Subramoney; Naume Tebeila; Derek Tshiabuila; Joseph Tsui; Stephanie van Wyk; Steven Weaver; Constantinos K. Wibmer; Eduan Wilkinson; Nicole Wolter; Alexander E. Zarebski; Boitumelo Zuze; Dominique Goedhals; Wolfgang Preiser; Florette Treurnicht; Marietje Venter; Carolyn Williamson; Oliver G. Pybus; Jinal Bhiman; Allison Glass; Darren P. Martin; Andrew Rambaut; Simani Gaseitsiwe; Anne von Gottberg; Tulio de Oliveira
<jats:title>Abstract</jats:title><jats:p>The SARS-CoV-2 epidemic in southern Africa has been characterized by three distinct waves. The first was associated with a mix of SARS-CoV-2 lineages, while the second and third waves were driven by the Beta (B.1.351) and Delta (B.1.617.2) variants, respectively<jats:sup>1–3</jats:sup>. In November 2021, genomic surveillance teams in South Africa and Botswana detected a new SARS-CoV-2 variant associated with a rapid resurgence of infections in Gauteng province, South Africa. Within three days of the first genome being uploaded, it was designated a variant of concern (Omicron, B.1.1.529) by the World Health Organization and, within three weeks, had been identified in 87 countries. The Omicron variant is exceptional for carrying over 30 mutations in the spike glycoprotein, which are predicted to influence antibody neutralization and spike function<jats:sup>4</jats:sup>. Here we describe the genomic profile and early transmission dynamics of Omicron, highlighting the rapid spread in regions with high levels of population immunity.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 679-686
SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters
Peter J. Halfmann; Shun Iida; Kiyoko Iwatsuki-Horimoto; Tadashi Maemura; Maki Kiso; Suzanne M. Scheaffer; Tamarand L. Darling; Astha Joshi; Samantha Loeber; Gagandeep Singh; Stephanie L. Foster; Baoling Ying; James Brett Case; Zhenlu Chong; Bradley Whitener; Juan Moliva; Katharine Floyd; Michiko Ujie; Noriko Nakajima; Mutsumi Ito; Ryan Wright; Ryuta Uraki; Prajakta Warang; Matthew Gagne; Rong Li; Yuko Sakai-Tagawa; Yanan Liu; Deanna Larson; Jorge E. Osorio; Juan P. Hernandez-Ortiz; Amy R. Henry; Karl Ciuoderis; Kelsey R. Florek; Mit Patel; Abby Odle; Lok-Yin Roy Wong; Allen C. Bateman; Zhongde Wang; Venkata-Viswanadh Edara; Zhenlu Chong; John Franks; Trushar Jeevan; Thomas Fabrizio; Jennifer DeBeauchamp; Lisa Kercher; Patrick Seiler; Ana Silvia Gonzalez-Reiche; Emilia Mia Sordillo; Lauren A. Chang; Harm van Bakel; Viviana Simon; B. Alburquerque; H. Alshammary; A. A. Amoako; S. Aslam; R. Banu; C. Cognigni; M. Espinoza-Moraga; K. Farrugia; A. van de Guchte; Z. Khalil; M. Laporte; I. Mena; A. E. Paniz-Mondolfi; J. Polanco; A. Rooker; L. A. Sominsky; Daniel C. Douek; Nancy J. Sullivan; Larissa B. Thackray; Hiroshi Ueki; Seiya Yamayoshi; Masaki Imai; Stanley Perlman; Richard J. Webby; Robert A. Seder; Mehul S. Suthar; Adolfo García-Sastre; Michael Schotsaert; Tadaki Suzuki; Adrianus C. M. Boon; Michael S. Diamond; Yoshihiro Kawaoka;
<jats:title>Abstract</jats:title><jats:p>The recent emergence of B.1.1.529, the Omicron variant<jats:sup>1,2</jats:sup>, has raised concerns of escape from protection by vaccines and therapeutic antibodies. A key test for potential countermeasures against B.1.1.529 is their activity in preclinical rodent models of respiratory tract disease. Here, using the collaborative network of the SARS-CoV-2 Assessment of Viral Evolution (SAVE) programme of the National Institute of Allergy and Infectious Diseases (NIAID), we evaluated the ability of several B.1.1.529 isolates to cause infection and disease in immunocompetent and human ACE2 (hACE2)-expressing mice and hamsters. Despite modelling data indicating that B.1.1.529 spike can bind more avidly to mouse ACE2 (refs. <jats:sup>3,4</jats:sup>), we observed less infection by B.1.1.529 in 129, C57BL/6, BALB/c and K18-hACE2 transgenic mice than by previous SARS-CoV-2 variants, with limited weight loss and lower viral burden in the upper and lower respiratory tracts. In wild-type and hACE2 transgenic hamsters, lung infection, clinical disease and pathology with B.1.1.529 were also milder than with historical isolates or other SARS-CoV-2 variants of concern. Overall, experiments from the SAVE/NIAID network with several B.1.1.529 isolates demonstrate attenuated lung disease in rodents, which parallels preliminary human clinical data.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 687-692