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Nature

Resumen/Descripción – provisto por la editorial en inglés
Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.
Palabras clave – provistas por la editorial

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Disponibilidad
Institución detectada Período Navegá Descargá Solicitá
No detectada desde jul. 2012 / hasta dic. 2023 Nature.com
No detectada desde jul. 2006 / hasta ago. 2012 Ovid

Información

Tipo de recurso:

revistas

ISSN impreso

0028-0836

ISSN electrónico

1476-4687

Editor responsable

Springer Nature

País de edición

Reino Unido

Fecha de publicación

Tabla de contenidos

High-fidelity laser-free universal control of trapped ion qubits

R. SrinivasORCID; S. C. Burd; H. M. Knaack; R. T. SutherlandORCID; A. Kwiatkowski; S. Glancy; E. Knill; D. J. Wineland; D. Leibfried; A. C. WilsonORCID; D. T. C. Allcock; D. H. SlichterORCID

Palabras clave: Multidisciplinary.

Pp. 209-213

Tunable self-assembled Casimir microcavities and polaritons

Battulga MunkhbatORCID; Adriana Canales; Betül Küçüköz; Denis G. BaranovORCID; Timur O. ShegaiORCID

Palabras clave: Multidisciplinary.

Pp. 214-219

Transmembrane transport in inorganic colloidal cell-mimics

Zhe XuORCID; Theodore Hueckel; William T. M. IrvineORCID; Stefano SacannaORCID

Palabras clave: Multidisciplinary.

Pp. 220-224

Widespread woody plant use of water stored in bedrock

Erica L. McCormickORCID; David N. DralleORCID; W. Jesse Hahm; Alison K. TuneORCID; Logan M. Schmidt; K. Dana ChadwickORCID; Daniella M. Rempe

Palabras clave: Multidisciplinary.

Pp. 225-229

Unextractable fossil fuels in a 1.5 °C world

Dan WelsbyORCID; James Price; Steve PyeORCID; Paul Ekins

Palabras clave: Multidisciplinary.

Pp. 230-234

A Triassic stem lepidosaur illuminates the origin of lizard-like reptiles

Ricardo N. MartínezORCID; Tiago R. SimõesORCID; Gabriela SobralORCID; Sebastián Apesteguía

Palabras clave: Multidisciplinary.

Pp. 235-238

Chronic social isolation signals starvation and reduces sleep in Drosophila

Wanhe LiORCID; Zikun Wang; Sheyum SyedORCID; Cheng Lyu; Samantha Lincoln; Jenna O’Neil; Andrew D. Nguyen; Irena FengORCID; Michael W. Young

Palabras clave: Multidisciplinary.

Pp. 239-244

Hypothalamic dopamine neurons motivate mating through persistent cAMP signalling

Stephen X. Zhang; Andrew Lutas; Shang YangORCID; Adriana Diaz; Hugo Fluhr; Georg Nagel; Shiqiang GaoORCID; Mark L. AndermannORCID

Palabras clave: Multidisciplinary.

Pp. 245-249

Cells of the human intestinal tract mapped across space and time

Rasa ElmentaiteORCID; Natsuhiko KumasakaORCID; Kenny RobertsORCID; Aaron Fleming; Emma DannORCID; Hamish W. KingORCID; Vitalii Kleshchevnikov; Monika Dabrowska; Sophie Pritchard; Liam BoltORCID; Sara F. VieiraORCID; Lira MamanovaORCID; Ni Huang; Francesca Perrone; Issac Goh Kai’En; Steven N. Lisgo; Matilda KatanORCID; Steven Leonard; Thomas R. W. OliverORCID; C. Elizabeth Hook; Komal Nayak; Lia S. Campos; Cecilia Domínguez CondeORCID; Emily Stephenson; Justin Engelbert; Rachel A. BottingORCID; Krzysztof PolanskiORCID; Stijn van Dongen; Minal Patel; Michael D. MorganORCID; John C. MarioniORCID; Omer Ali BayraktarORCID; Kerstin B. MeyerORCID; Xiaoling He; Roger A. Barker; Holm H. UhligORCID; Krishnaa T. MahbubaniORCID; Kourosh Saeb-ParsyORCID; Matthias ZilbauerORCID; Menna R. Clatworthy; Muzlifah HaniffaORCID; Kylie R. JamesORCID; Sarah A. TeichmannORCID

<jats:title>Abstract</jats:title><jats:p>The cellular landscape of the human intestinal tract is dynamic throughout life, developing in utero and changing in response to functional requirements and environmental exposures. Here, to comprehensively map cell lineages, we use single-cell RNA sequencing and antigen receptor analysis of almost half a million cells from up to 5 anatomical regions in the developing and up to 11 distinct anatomical regions in the healthy paediatric and adult human gut. This reveals the existence of transcriptionally distinct BEST4 epithelial cells throughout the human intestinal tract. Furthermore, we implicate IgG sensing as a function of intestinal tuft cells. We describe neural cell populations in the developing enteric nervous system, and predict cell-type-specific expression of genes associated with Hirschsprung’s disease. Finally, using a systems approach, we identify key cell players that drive the formation of secondary lymphoid tissue in early human development. We show that these programs are adopted in inflammatory bowel disease to recruit and retain immune cells at the site of inflammation. This catalogue of intestinal cells will provide new insights into cellular programs in development, homeostasis and disease.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 250-255

Aged skeletal stem cells generate an inflammatory degenerative niche

Thomas H. AmbrosiORCID; Owen MarecicORCID; Adrian McArdle; Rahul Sinha; Gunsagar S. GulatiORCID; Xinming Tong; Yuting Wang; Holly M. Steininger; Malachia Y. Hoover; Lauren S. Koepke; Matthew P. MurphyORCID; Jan Sokol; Eun Young Seo; Ruth Tevlin; Michael Lopez; Rachel E. Brewer; Shamik Mascharak; Laura Lu; Oyinkansola Ajanaku; Stephanie D. Conley; Jun Seita; Maurizio Morri; Norma F. NeffORCID; Debashis SahooORCID; Fan Yang; Irving L. Weissman; Michael T. LongakerORCID; Charles K. F. ChanORCID

Palabras clave: Multidisciplinary.

Pp. 256-262