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Nature

Resumen/Descripción – provisto por la editorial en inglés
Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.
Palabras clave – provistas por la editorial

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Disponibilidad
Institución detectada Período Navegá Descargá Solicitá
No detectada desde jul. 2012 / hasta dic. 2023 Nature.com
No detectada desde jul. 2006 / hasta ago. 2012 Ovid

Información

Tipo de recurso:

revistas

ISSN impreso

0028-0836

ISSN electrónico

1476-4687

Editor responsable

Springer Nature

País de edición

Reino Unido

Fecha de publicación

Tabla de contenidos

Endothelial sensing of AHR ligands regulates intestinal homeostasis

Benjamin G. WigginsORCID; Yi-Fang Wang; Alice Burke; Nil Grunberg; Julia M. Vlachaki Walker; Marian Dore; Catherine ChahrourORCID; Betheney R. PennycookORCID; Julia Sanchez-GarridoORCID; Santiago VerniaORCID; Alexis R. BarrORCID; Gad FrankelORCID; Graeme M. BirdseyORCID; Anna M. RandiORCID; Chris SchieringORCID

Palabras clave: Multidisciplinary.

Pp. No disponible

How to be successful as a research mathematician? Follow your gut

Davide Castelvecchi

Palabras clave: Multidisciplinary.

Pp. 485-486

Evelyn Boyd Granville, space-flight trailblazer (1924—2023)

Mar Hicks

Palabras clave: Multidisciplinary.

Pp. 487-487

How to reduce Africa’s undue exposure to climate risks

Asaf Tzachor; Catherine E. Richards; Masilin Gudoshava; Patricia Nying’uro; Herbert Misiani; Jemimah G. Ongoma; Yoav Yair; Yacob Mulugetta; Amadou T. Gaye

Palabras clave: Multidisciplinary.

Pp. 488-491

Can oyster farming help save the planet?

Linda Nordling

Palabras clave: Multidisciplinary.

Pp. 690-690

COVID infection risk rises the longer you are exposed — even for vaccinated people

Anil Oza

Palabras clave: Multidisciplinary.

Pp. No disponible

A pentameric TRPV3 channel with a dilated pore

Shifra LanskyORCID; John Michael Betancourt; Jingying Zhang; Yining JiangORCID; Elizabeth D. Kim; Navid PaknejadORCID; Crina M. NimigeanORCID; Peng Yuan; Simon ScheuringORCID

Palabras clave: Multidisciplinary.

Pp. No disponible

Widespread retreat of coastal habitat is likely at warming levels above 1.5 °C

Neil SaintilanORCID; Benjamin HortonORCID; Torbjörn E. TörnqvistORCID; Erica L. AsheORCID; Nicole S. Khan; Mark SchuerchORCID; Chris PerryORCID; Robert E. KoppORCID; Gregory G. Garner; Nicholas MurrayORCID; Kerrylee RogersORCID; Simon Albert; Jeffrey Kelleway; Timothy A. Shaw; Colin D. Woodroffe; Catherine E. LovelockORCID; Madeline M. Goddard; Lindsay B. HutleyORCID; Katya Kovalenko; Laura Feher; Glenn GuntenspergenORCID

<jats:title>Abstract</jats:title><jats:p>Several coastal ecosystems—most notably mangroves and tidal marshes—exhibit biogenic feedbacks that are facilitating adjustment to relative sea-level rise (RSLR), including the sequestration of carbon and the trapping of mineral sediment<jats:sup>1</jats:sup>. The stability of reef-top habitats under RSLR is similarly linked to reef-derived sediment accumulation and the vertical accretion of protective coral reefs<jats:sup>2</jats:sup>. The persistence of these ecosystems under high rates of RSLR is contested<jats:sup>3</jats:sup>. Here we show that the probability of vertical adjustment to RSLR inferred from palaeo-stratigraphic observations aligns with contemporary in situ survey measurements. A deficit between tidal marsh and mangrove adjustment and RSLR is likely at 4 mm yr<jats:sup>−1</jats:sup> and highly likely at 7 mm yr<jats:sup>−1</jats:sup> of RSLR. As rates of RSLR exceed 7 mm yr<jats:sup>−1</jats:sup>, the probability that reef islands destabilize through increased shoreline erosion and wave over-topping increases. Increased global warming from 1.5 °C to 2.0 °C would double the area of mapped tidal marsh exposed to 4 mm yr<jats:sup>−1</jats:sup> of RSLR by between 2080 and 2100. With 3 °C of warming, nearly all the world’s mangrove forests and coral reef islands and almost 40% of mapped tidal marshes are estimated to be exposed to RSLR of at least 7 mm yr<jats:sup>−1</jats:sup>. Meeting the Paris agreement targets would minimize disruption to coastal ecosystems.</jats:p>

Palabras clave: Multidisciplinary.

Pp. No disponible

Gut microbial carbohydrate metabolism contributes to insulin resistance

Tadashi TakeuchiORCID; Tetsuya Kubota; Yumiko Nakanishi; Hiroshi TsugawaORCID; Wataru Suda; Andrew Tae-Jun Kwon; Junshi YazakiORCID; Kazutaka Ikeda; Shino Nemoto; Yoshiki Mochizuki; Toshimori KitamiORCID; Katsuyuki Yugi; Yoshiko Mizuno; Nobutake Yamamichi; Tsutomu YamazakiORCID; Iseki Takamoto; Naoto Kubota; Takashi KadowakiORCID; Erik ArnerORCID; Piero CarninciORCID; Osamu OharaORCID; Makoto AritaORCID; Masahira Hattori; Shigeo KoyasuORCID; Hiroshi OhnoORCID

<jats:title>Abstract</jats:title><jats:p>Insulin resistance is the primary pathophysiology underlying metabolic syndrome and type 2 diabetes<jats:sup>1,2</jats:sup>. Previous metagenomic studies have described the characteristics of gut microbiota and their roles in metabolizing major nutrients in insulin resistance<jats:sup>3–9</jats:sup>. In particular, carbohydrate metabolism of commensals has been proposed to contribute up to 10% of the host’s overall energy extraction<jats:sup>10</jats:sup>, thereby playing a role in the pathogenesis of obesity and prediabetes<jats:sup>3,4,6</jats:sup>. Nevertheless, the underlying mechanism remains unclear. Here we investigate this relationship using a comprehensive multi-omics strategy in humans. We combine unbiased faecal metabolomics with metagenomics, host metabolomics and transcriptomics data to profile the involvement of the microbiome in insulin resistance. These data reveal that faecal carbohydrates, particularly host-accessible monosaccharides, are increased in individuals with insulin resistance and are associated with microbial carbohydrate metabolisms and host inflammatory cytokines. We identify gut bacteria associated with insulin resistance and insulin sensitivity that show a distinct pattern of carbohydrate metabolism, and demonstrate that insulin-sensitivity-associated bacteria ameliorate host phenotypes of insulin resistance in a mouse model. Our study, which provides a comprehensive view of the host–microorganism relationships in insulin resistance, reveals the impact of carbohydrate metabolism by microbiota, suggesting a potential therapeutic target for ameliorating insulin resistance.</jats:p>

Palabras clave: Multidisciplinary.

Pp. No disponible

Structure evolution at the gate-tunable suspended graphene–water interface

Ying Xu; You-Bo Ma; Feng Gu; Shan-Shan Yang; Chuan-Shan TianORCID

Palabras clave: Multidisciplinary.

Pp. No disponible