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Biology of Inositols and Phosphoinositides: Subcellular Biochemistry

A. Lahiri Majumder ; B. B. Biswas (eds.)

Resumen/Descripción – provisto por la editorial

No disponible.

Palabras clave – provistas por la editorial

No disponibles.

Disponibilidad
Institución detectada Año de publicación Navegá Descargá Solicitá
No detectada 2006 SpringerLink

Información

Tipo de recurso:

libros

ISBN impreso

978-0-387-27599-4

ISBN electrónico

978-0-387-27600-7

Editor responsable

Springer Nature

País de edición

Reino Unido

Fecha de publicación

Información sobre derechos de publicación

© Springer 2006

Cobertura temática

Tabla de contenidos

Inositol Phosphates and Phosphoinositides in Health and Disease

Yihui Shi; Abed N. Azab; Morgan N. Thompson; Miriam L. Greenberg

In the past two decades, considerable progress has been made toward understanding inositol phosphates and PI metabolism. However, there is still much to learn. The present challenge is to understand how inositol phosphates and PIs are compartmentalized, identify new targets of inositol phosphates and PIs, and elucidate the mechanisms underlying spatial and temporal regulation of the enzymes that metabolize inositol phosphates and PIs. Answers to these questions will help clarify the mechanisms of the diseases associated with these molecules and identify new possibilities for drug design.

Palabras clave: Inositol Phosphate; Malignant Hyperthermia; Malignant Hyperthermia; GLUT4 Translocation; Inositol Polyphosphate.

Pp. 265-292

Mammalian Inositol 3-phosphate Synthase: Its Role in the Biosynthesis of Brain Inositol and its Clinical Use as a Psychoactive Agent

Latha K. Parthasarathy; L. Ratnam; S. Seelan; Carmelita Tobias; Manuel F. Casanova; Ranga N. Parthasarathy

Palabras clave: Binge Eating; Bulimia Nervosa; Electrophoretic Mobility Shift Assay; Panic Disorder; Minimal Promoter.

Pp. 293-314

Evolutionary Divergence of L-myo-Inositol 1-Phosphate Synthase: Significance of a “Core Catalytic Structure”

Krishnarup Ghosh Dastidar; Aparajita Chatterjee; Anirban Chatterjee; Arun Lahiri Majumder

Palabras clave: INO1 Gene; MIPS Gene; Core Catalytic Domain; MIPS Protein; Active Site Amino Acid Residue.

Pp. 315-340