Catálogo de publicaciones - libros

Compartir en
redes sociales


Stem Cells and their Potential for Clinical Application

Nadja M. Bilko ; Boris Fehse ; Wolfram Ostertag ; Carol Stocking ; Axel R. Zander (eds.)

Resumen/Descripción – provisto por la editorial

No disponible.

Palabras clave – provistas por la editorial

Hematology; Cancer Research; Molecular Medicine; Cell Biology; Immunology

Disponibilidad
Institución detectada Año de publicación Navegá Descargá Solicitá
No detectada 2008 SpringerLink

Información

Tipo de recurso:

libros

ISBN impreso

978-1-4020-6467-8

ISBN electrónico

978-1-4020-6469-2

Editor responsable

Springer Nature

País de edición

Reino Unido

Fecha de publicación

Información sobre derechos de publicación

© Springer Netherlands 2008

Tabla de contenidos

Anti Thymocyte Globuline Allows for Successful Transplantation from HLA Mismatched Unrelated Donors

Axel R. Zander; Tatjana Zabelina; Francis Ayuk; Christine Wolschke; Olga Waschke; Gitta Amtsfeld; Thomas Eiermann; Hartmut Kabisch; Boris Fehse; Jürgen Berger; Rudolf Erttmann; Nicolaus M. Kröger

Allogeneic hemopoietic stem cell transplantation of matched unrelated donors carries an increased risk of graft versus host disease (GvHD) and transplant related mortality (TRM). We introduced ATG Fresenius at median dose of 90 mg/kg body weight as part of the conditioning regimen for prevention of serious GvHD. We compared 48 recipients of mismatched transplants with 170 recipients of an HLA-matched transplant. The mismatches involved one or two loci. The groups differed in age [HLA-matched: 33 years (0,9–61) HLA-mismatched: 21 years (0,9–51)] and graft source, bone marrow versus peripheral blood stem cell (matched 67% bone marrow, mismatched 83% bone marrow). They were comparable in diagnosis, stage of disease and conditioning. Key words: Mismatched unrelated donor, anti-thymocyte-globuline, stem cell transplantation

Palabras clave: Chronic Myelogenous Leukemia; Graft Versus Host Disease; Peripheral Blood Stem Cell; Unrelated Donor; Transplant Related Mortality.

V - Clinical Haematopoietic Stem Cell Transplantation | Pp. 263-274