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Fitofarmacovigilanza: Vigilanza sulla sicurezza dei prodotti fitoterapici

Francesco Capasso Francesca Borrelli Stefano Castaldo Giuliano Grandolini

Resumen/Descripción – provisto por la editorial

No disponible.

Palabras clave – provistas por la editorial

Pharmacy; Health Promotion and Disease Prevention

Disponibilidad
Institución detectada Año de publicación Navegá Descargá Solicitá
No detectada 2006 SpringerLink

Información

Tipo de recurso:

libros

ISBN impreso

978-88-470-0478-8

ISBN electrónico

978-88-470-0479-5

Editor responsable

Springer Nature

País de edición

Reino Unido

Fecha de publicación

Información sobre derechos de publicación

© Springer-Verlag Italia 2006

Cobertura temática

Tabla de contenidos

Introduzione

Francesco Capasso; Francesca Borrelli; Stefano Castaldo; Giuliano Grandolini

Despite many proven advances in patient care over the last 10 years, asthma continues to impose a large and growing burden on society. Persistent clinician non-adherence to recommended practice is well documented, but little is known about the clinical impact and economic costs of alternative approaches to asthma patient care. In this chapter, we introduce the Asthma Policy Model, a state-transition simulation that we have developed to forecast asthma-related symptoms, acute exacerbations, quality-adjusted life expectancy, health care costs, and cost-effectiveness. We begin with a detailed survey of the epidemiological, clinical, and policy context that motivates our work. With a modeling audience in mind, we then describe the considerations that produced the current analytic structure and input datasets. We illustrate the policy relevance of the model by describing our recent work on the cost-effectiveness of inhaled corticosteroid therapy in a population of adult patients with mild-to-moderate disease. We close the chapter with a discussion of plans for future refinements and applications.

Pp. 1-14

Dall’eclissi alla rinascita del farmaco naturale

Francesco Capasso; Francesca Borrelli; Stefano Castaldo; Giuliano Grandolini

Despite many proven advances in patient care over the last 10 years, asthma continues to impose a large and growing burden on society. Persistent clinician non-adherence to recommended practice is well documented, but little is known about the clinical impact and economic costs of alternative approaches to asthma patient care. In this chapter, we introduce the Asthma Policy Model, a state-transition simulation that we have developed to forecast asthma-related symptoms, acute exacerbations, quality-adjusted life expectancy, health care costs, and cost-effectiveness. We begin with a detailed survey of the epidemiological, clinical, and policy context that motivates our work. With a modeling audience in mind, we then describe the considerations that produced the current analytic structure and input datasets. We illustrate the policy relevance of the model by describing our recent work on the cost-effectiveness of inhaled corticosteroid therapy in a population of adult patients with mild-to-moderate disease. We close the chapter with a discussion of plans for future refinements and applications.

Pp. 15-18

I rischi in fitoterapia: l’entità del problema

Francesco Capasso; Francesca Borrelli; Stefano Castaldo; Giuliano Grandolini

Despite many proven advances in patient care over the last 10 years, asthma continues to impose a large and growing burden on society. Persistent clinician non-adherence to recommended practice is well documented, but little is known about the clinical impact and economic costs of alternative approaches to asthma patient care. In this chapter, we introduce the Asthma Policy Model, a state-transition simulation that we have developed to forecast asthma-related symptoms, acute exacerbations, quality-adjusted life expectancy, health care costs, and cost-effectiveness. We begin with a detailed survey of the epidemiological, clinical, and policy context that motivates our work. With a modeling audience in mind, we then describe the considerations that produced the current analytic structure and input datasets. We illustrate the policy relevance of the model by describing our recent work on the cost-effectiveness of inhaled corticosteroid therapy in a population of adult patients with mild-to-moderate disease. We close the chapter with a discussion of plans for future refinements and applications.

Pp. 19-23

Come limitare i rischi da fitoterapici

Francesco Capasso; Francesca Borrelli; Stefano Castaldo; Giuliano Grandolini

Despite many proven advances in patient care over the last 10 years, asthma continues to impose a large and growing burden on society. Persistent clinician non-adherence to recommended practice is well documented, but little is known about the clinical impact and economic costs of alternative approaches to asthma patient care. In this chapter, we introduce the Asthma Policy Model, a state-transition simulation that we have developed to forecast asthma-related symptoms, acute exacerbations, quality-adjusted life expectancy, health care costs, and cost-effectiveness. We begin with a detailed survey of the epidemiological, clinical, and policy context that motivates our work. With a modeling audience in mind, we then describe the considerations that produced the current analytic structure and input datasets. We illustrate the policy relevance of the model by describing our recent work on the cost-effectiveness of inhaled corticosteroid therapy in a population of adult patients with mild-to-moderate disease. We close the chapter with a discussion of plans for future refinements and applications.

Pp. 25-58

Fitofarmacovigilanza: obiettivi

Francesco Capasso; Francesca Borrelli; Stefano Castaldo; Giuliano Grandolini

Despite many proven advances in patient care over the last 10 years, asthma continues to impose a large and growing burden on society. Persistent clinician non-adherence to recommended practice is well documented, but little is known about the clinical impact and economic costs of alternative approaches to asthma patient care. In this chapter, we introduce the Asthma Policy Model, a state-transition simulation that we have developed to forecast asthma-related symptoms, acute exacerbations, quality-adjusted life expectancy, health care costs, and cost-effectiveness. We begin with a detailed survey of the epidemiological, clinical, and policy context that motivates our work. With a modeling audience in mind, we then describe the considerations that produced the current analytic structure and input datasets. We illustrate the policy relevance of the model by describing our recent work on the cost-effectiveness of inhaled corticosteroid therapy in a population of adult patients with mild-to-moderate disease. We close the chapter with a discussion of plans for future refinements and applications.

Pp. 59-61

La segnalazione spontanea e i suoi limiti

Francesco Capasso; Francesca Borrelli; Stefano Castaldo; Giuliano Grandolini

Despite many proven advances in patient care over the last 10 years, asthma continues to impose a large and growing burden on society. Persistent clinician non-adherence to recommended practice is well documented, but little is known about the clinical impact and economic costs of alternative approaches to asthma patient care. In this chapter, we introduce the Asthma Policy Model, a state-transition simulation that we have developed to forecast asthma-related symptoms, acute exacerbations, quality-adjusted life expectancy, health care costs, and cost-effectiveness. We begin with a detailed survey of the epidemiological, clinical, and policy context that motivates our work. With a modeling audience in mind, we then describe the considerations that produced the current analytic structure and input datasets. We illustrate the policy relevance of the model by describing our recent work on the cost-effectiveness of inhaled corticosteroid therapy in a population of adult patients with mild-to-moderate disease. We close the chapter with a discussion of plans for future refinements and applications.

Pp. 63-68

Le reazioni avverse da fitoterapici: definizione, classificazione e loro individuazione

Francesco Capasso; Francesca Borrelli; Stefano Castaldo; Giuliano Grandolini

Despite many proven advances in patient care over the last 10 years, asthma continues to impose a large and growing burden on society. Persistent clinician non-adherence to recommended practice is well documented, but little is known about the clinical impact and economic costs of alternative approaches to asthma patient care. In this chapter, we introduce the Asthma Policy Model, a state-transition simulation that we have developed to forecast asthma-related symptoms, acute exacerbations, quality-adjusted life expectancy, health care costs, and cost-effectiveness. We begin with a detailed survey of the epidemiological, clinical, and policy context that motivates our work. With a modeling audience in mind, we then describe the considerations that produced the current analytic structure and input datasets. We illustrate the policy relevance of the model by describing our recent work on the cost-effectiveness of inhaled corticosteroid therapy in a population of adult patients with mild-to-moderate disease. We close the chapter with a discussion of plans for future refinements and applications.

Pp. 69-73

La sperimentazione clinica: in molti casi una opportunità, ma anche una necessità

Francesco Capasso; Francesca Borrelli; Stefano Castaldo; Giuliano Grandolini

Despite many proven advances in patient care over the last 10 years, asthma continues to impose a large and growing burden on society. Persistent clinician non-adherence to recommended practice is well documented, but little is known about the clinical impact and economic costs of alternative approaches to asthma patient care. In this chapter, we introduce the Asthma Policy Model, a state-transition simulation that we have developed to forecast asthma-related symptoms, acute exacerbations, quality-adjusted life expectancy, health care costs, and cost-effectiveness. We begin with a detailed survey of the epidemiological, clinical, and policy context that motivates our work. With a modeling audience in mind, we then describe the considerations that produced the current analytic structure and input datasets. We illustrate the policy relevance of the model by describing our recent work on the cost-effectiveness of inhaled corticosteroid therapy in a population of adult patients with mild-to-moderate disease. We close the chapter with a discussion of plans for future refinements and applications.

Pp. 75-83

Danni prodotti dal fitoterapico

Francesco Capasso; Francesca Borrelli; Stefano Castaldo; Giuliano Grandolini

Despite many proven advances in patient care over the last 10 years, asthma continues to impose a large and growing burden on society. Persistent clinician non-adherence to recommended practice is well documented, but little is known about the clinical impact and economic costs of alternative approaches to asthma patient care. In this chapter, we introduce the Asthma Policy Model, a state-transition simulation that we have developed to forecast asthma-related symptoms, acute exacerbations, quality-adjusted life expectancy, health care costs, and cost-effectiveness. We begin with a detailed survey of the epidemiological, clinical, and policy context that motivates our work. With a modeling audience in mind, we then describe the considerations that produced the current analytic structure and input datasets. We illustrate the policy relevance of the model by describing our recent work on the cost-effectiveness of inhaled corticosteroid therapy in a population of adult patients with mild-to-moderate disease. We close the chapter with a discussion of plans for future refinements and applications.

Pp. 85-120

Danni prodotti dall’associazione fitoterapico/farmaco convenzionale e fitoterapico/alimento

Francesco Capasso; Francesca Borrelli; Stefano Castaldo; Giuliano Grandolini

Despite many proven advances in patient care over the last 10 years, asthma continues to impose a large and growing burden on society. Persistent clinician non-adherence to recommended practice is well documented, but little is known about the clinical impact and economic costs of alternative approaches to asthma patient care. In this chapter, we introduce the Asthma Policy Model, a state-transition simulation that we have developed to forecast asthma-related symptoms, acute exacerbations, quality-adjusted life expectancy, health care costs, and cost-effectiveness. We begin with a detailed survey of the epidemiological, clinical, and policy context that motivates our work. With a modeling audience in mind, we then describe the considerations that produced the current analytic structure and input datasets. We illustrate the policy relevance of the model by describing our recent work on the cost-effectiveness of inhaled corticosteroid therapy in a population of adult patients with mild-to-moderate disease. We close the chapter with a discussion of plans for future refinements and applications.

Pp. 121-147