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EPR Effect-Based Tumor Targeted Nanomedicine

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extracellular matrix; drug delivery; tumor; cancer; targeting; reactive oxygen species; antioxidant; self-assembling drug; HPMA copolymers; EPR effect; controlled release; nanomedicines; nanoparticles; tumor vascular regulation; angiogenesis; blood perfusion; vascular permeability; tumor targeting; photodynamic; hyaluronan; zinc protoporphyrin; enhanced permeability and retention effect; cancer therapy; nanotechnology; tumor-selective drug delivery; photodynamic therapy; boron neutron capture therapy; isosorbide dinitrate; sildenafil citrate; EPR-effect enhancers; heterogeneity of the EPR effect; nitric oxide donors; tumor blood flow; TNBC; dasatinib; poly(styrene-co-maleic acid) micelles; nanoformulation; metabolism; EPR; nanomedicine; targeted therapy; solid cancer; microenvironment; hypoxia; DDS; anaerobic bacteria; Bifidobacterium; bacterial therapy; iDPS; EPR-based therapy; passive targeting; heterogeneity; solid-tumor; EPR-imaging techniques; sildenafil; phosphodiesterase 5 inhibitors; drug repurposing; chemoadjuvant; arterial infusion; canine cancer; particle beam therapy; proton beam therapy; carbon-ion beam therapy; combination therapy; iNaD; siRNA; microRNA; calcium phosphate; PEG blending; cancer treatment; n/a

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