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Palabras clave – provistas por la editorial

Aggregatibacter actinomycetemcomitans; cagE; virB1; virB4; genotype; virulence; mRNA assay; quantitative ELISA; cell lysis assay; leukotoxin; JP2 genotype; cytolethal distending toxin; lipopolysaccharides; cytokine binding factors; horizontal gene transfer; outer membrane vesicles; biofilm; proteomic; adherence; endocarditis; fimbriae; JP2; periodontitis; taxonomy; core and accessory genes; average nucleotide identity; principal component analysis; keratins; organotypic gingival mucosa; A. actinomycetemcomitans; RNA-Seq; genomic islands; core genes; accessory genes; stress; nutrient limitation; differentially expressed genes.; lymphocytes; apoptosis; RTX toxin; localized aggressive periodontitis; LFA-1; leukotoxin (LtxA); endocytosis; n/a; JP2 clone of Aggregatibacter actinomycetemcomitans; JP2 in Caucasian; microbiological diagnosis; adjunctive antibiotics; localized aggressive periodontitis: animal studies: human studies; landscape ecology; damage/response framework; bacteremia; horseshoe crab; Origanum vulgare; essential oil; antimicrobial activity; minimum inhibitory concentration; minimal bactericidal concentration; cytotoxicity; leukotoxin neutralization; inflammasome; immune response; periodontal disease; proteomics