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Annual Review of Nutrition

Resumen/Descripción – provisto por la editorial en inglés
The Annual Review of Nutrition, in publication since 1981, covers the significant developments in the field of Nutrition, including Energy Metabolism, Carbohydrates, Lipids, Proteins and Amino Acids, Vitamins, Minerals, Nutrient Transport and Function, Metabolic Regulation, Nutritional Genomics, Molecular and Cell Biology, Clinical Nutrition, Comparative Nutrition, Nutritional Anthropology, Nutritional Toxicology, Nutritional Microbiology, Epidemiology, and Public Health Nutrition.
Palabras clave – provistas por la editorial

No disponibles.

Disponibilidad
Institución detectada Período Navegá Descargá Solicitá
No detectada desde ene. 1981 / hasta dic. 2023 Annual Reviews

Información

Tipo de recurso:

revistas

ISSN impreso

0199-9885

ISSN electrónico

1545-4312

Editor responsable

Annual Reviews Inc.

País de edición

Estados Unidos

Fecha de publicación

Tabla de contenidos

Malnourished Microbes: Host–Microbiome Interactions in Child Undernutrition

Helen J. Jones; Claire D. Bourke; Jonathan R. Swann; Ruairi C. Robertson

<jats:p> Childhood undernutrition is a major global health burden that is only partially resolved by nutritional interventions. Both chronic and acute forms of child undernutrition are characterized by derangements in multiple biological systems including metabolism, immunity, and endocrine systems. A growing body of evidence supports a role of the gut microbiome in mediating these pathways influencing early life growth. Observational studies report alterations in the gut microbiome of undernourished children, while preclinical studies suggest that this can trigger intestinal enteropathy, alter host metabolism, and disrupt immune-mediated resistance against enteropathogens, each of which contribute to poor early life growth. Here, we compile evidence from preclinical and clinical studies and describe the emerging pathophysiological pathways by which the early life gut microbiome influences host metabolism, immunity, intestinal function, endocrine regulation, and other pathways contributing to child undernutrition. We discuss emerging microbiome-directed therapies and consider future research directions to identify and target microbiome-sensitive pathways in child undernutrition. </jats:p><jats:p> Expected final online publication date for the Annual Review of Nutrition, Volume 43 is August 2023. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates. </jats:p>

Palabras clave: Nutrition and Dietetics; Medicine (miscellaneous).

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