Catálogo de publicaciones - tesis
Título de Acceso Abierto
Modelling and simulation of microfluidic chips for analytical aplications
Pablo Alejandro Kler Fabio Ariel Guarnieri Alejandro Allevi Jorge D'Elia Salvador Ortiz Claudio Luis Alberto Berli
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Resumen/Descripción – provisto por el repositorio digital
Lab-on-a-Chips (LOC) are microdevices that integrate one or several laboratory functions on a single chip of a few square centimeters. LOC provide a platform to conduct chemical and biochemical analysis in a wide variety of scientific areas. Numerical simulations of LOC are extremely useful at design and optimization stages. They can provide a more complete understanding of the fundamental physical and chemical process that occur in LOC. Also, numerical simulations are useful for the optimization of parameters for geometry and operation, minimizing the risk of wasting time and money in a flawed design. The main contribution of this thesis is the development and testing of a set of numerical tools that are aimed to improve the design and develop of LOC. The several physicochemical fields involved and the special considerations required due to the high aspect ratios between length scales involved, determine the complexity of modelling and the computational cost. Along this thesis different numerical modelling approaches are presented in order to show different options to deal with these problems. Several examples of numerical simulation for analytical processes in LOC are presented. Some of them are devoted to validate the mathematical model and the simulation tools developed. Other examples consist in simulations of different experimental analytical process performed in LOC that are aimed to illustrate the proficiency of the numerical model to simulate a wide variety of LOC analytical applications.Palabras clave – provistas por el repositorio digital
Microfluidic chips; Numerical simulation; Electrophoretic separation; Finite element method; Chips microfluídicos; Simulación numérica; Separaciones electroforéticas; Método de elementos finitos
Disponibilidad
| Institución detectada | Año de publicación | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No requiere | 2011 | Biblioteca Virtual de la Universidad Nacional del Litoral (SNRD) |
|
Información
Tipo de recurso:
tesis
Idiomas de la publicación
- inglés
País de edición
Argentina
Fecha de publicación
2011-05-23