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Modelado, simulación y fabricación de una microválvula para glaucoma

Fernando Leonel Sassetti Fabio Ariel Guarnieri Diego Martín Campana Rodrigo Martín Torres José Luis Fernández Salvador Ortiz

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Resumen/Descripción – provisto por el repositorio digital
Glaucoma is a group of pathologies associated with the progressive damage of the optic nerve that leads to blindness. In patients with glaucoma, treatments reduce intraocular pressure through medications or implanted devices. This thesis is based on the specifications described in the Patent of Invention AR058947 "Microaparate implantable in the eye to alleviate glaucoma or ocular pressure-causing disease" where it is proposed the manufacture of an active device for the control of the flow of aqueous humor based on the use of conductive polymers. For the design and simulation of the operation of the devices, computational tools based on the finite element method were used. In particular, a fluid-structure model of the hydraulic-actuator module and a solid bilayer thermoelastic model of the actuator were implemented. Eye-valve system models were implemented using electrical circuits and ordinary differential equations systems in Matlab's Simulink. Molds were designed and built for the manufacture of hydraulic modules with biocompatible elastomers, using 3D printers and numerical control milling machines. Linear actuators (beams) and diaphragms for the microvalves based on conductive polymers were manufactured, they were characterized by electrochemical techniques and kinematic measurements. The linear actuators manufactured from Kapton-PPy (DBS). The resistances obtained in the hydraulic modules of the valves manufactured are below the expected values for the microvalve, the characteristics of the manufactured actuators are close to the values reported in the literature.
Palabras clave – provistas por el repositorio digital

Microvalve; Glaucoma; Model; Finite element; Microválvula; Modelos; Elementos Finitos

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No requiere 2016 Biblioteca Virtual de la Universidad Nacional del Litoral (SNRD) acceso abierto

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Tipo de recurso:

tesis

Idiomas de la publicación

  • español castellano

País de edición

Argentina

Fecha de publicación

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