Catálogo de publicaciones

Interpreting Biomedical Science: Experiment, Evidence, and Belief discusses what can go wrong in biological science, providing an unbiased view and cohesive understanding of scientific methods, statistics, data interpretation, and scientific ethics that are illustrated with practical examples and real-life applications.

Casting a wide net, the reader is exposed to scientific problems and solutions through informed perspectives from history, philosophy, sociology, and the social psychology of science.

The book shows the differences and similarities between disciplines and different eras and illustrates the concept that while sound methodology is necessary for the progress of science, we cannot succeed without a right culture of doing things.

• Features theoretical concepts accompanied by examples from biological literature
• Contains an introduction to various methods, with an emphasis on statistical hypothesis testing
• Presents a clear argument that ties the motivations and ethics of individual scientists to the success of their science
• Provides recommendations on how to safeguard against scientific misconduct, fraud, and retractions
• Arms young scientists with practical knowledge that they can use every day

Comprising by far the largest and most diverse group of vertebrates, fishes occupy a broad swathe of habitats ranging from the deepest ocean abyss to the highest mountain lakes. Such incredible ecological diversity and the resultant variety in lifestyle, anatomy, physiology and behavior, make unraveling the evolutionary history of fishes a daunting task.

The successor of a classic volume by the same title, Interrelationships of Fishes, provides the latest in the "state of the art" of systematics and classification for many of the major groups of fishes. In providing a sound phylogenetic framework from leading authorities in the field, this book is an indispensable reference for a broad range of biologists, especially students of fish behavior, anatomy, physiology, molecular biology, genetics and ecology--in fact, anyone who wishes to interpret their work on fishes in an evolutionary context.

• Provides thorough and comprehensive treatment of the Phylogency of fishes
• Assembles an International team of expert contributors
• Useful to a wide variety of fish biologists

Intertidal Fishes describes the fishes inhabiting the narrow strip of habitat between the high and low tide marks along the rocky coastlines of the world. It analyzes the specialized traits of these fishes that have adapted to living in the dynamic and challenging space where they are alternately exposed to the air and submerged in water with the ebb and flow of the tides. This book provides a comprehensive account of fishes largely overlooked in many previous studies of intertidal organisms and emphasizes how they differ from fishes living in other deeper-water habitats. Coverage includes air breathing, movements and homing, sensory systems, spawning and parental care, feeding habits, community structure, systematic relationships, distribution patterns, and the fossil record in the intertidal zone.

Key Features
* Written by an international team of 21 experts on intertidal fish biology
* Worldwide coverage of intertidal fishes
* Comprehensive phylogenetic listing of all fish families with intertidal members
* Global biogeographic analysis involving over 700 species from 86 sites
* Outlines field and laboratory methods pertinent to studying intertidal fishes
* Thorough ecological coverage with chapters on vertical distribution, movements and homing, reproduction, feeding, and community structure
* Covers the physiology of aerial and aquatic respiration, osmoregulation, and sensory systems

• Obra perteneciente a la innovadora serie 'Requisitos en Gastroenterología', que aborda de una manera muy concisa pero completa los conocimientos esenciales en gastroenterología y hepatología: fisiopatología, diagnóstico, diagnóstico diferencial y manejo y tratamiento basado en la evidencia de los distintos trastornos gastrointestinales, hepáticos y pancreáticos. Esta serie se compone de cuatro volúmenes interrelacionados, aunque cada uno de ellos se puede leer y entender perfectamente por separado. Cada volumen está profusamente ilustrado y contiene tablas y figuras que resaltan las características fundamentales de los distintos temas. Este volumen, el segundo de la serie, está dedicado al intestino delgado y el intestino grueso, órganos multifuncionales con una importante función, al ser responsables de la absorción de nutrientes, agua y electrólitos, por lo que alteraciones de cualquiera de los componentes anatómicos y fisiológicos del tracto intestinal dan lugar a estados patológicos, muchos de los cuales son causas importantes de morbimortalidad. En esta obra se revisan las entidades nosológicas más comunes asociadas con el tracto intestinal, como colitis ulcerosa, enfermedad de Crohn, diarrea aguda y crónica, neoplasias, intestino irritable, entre otras. Recoge la información clínicamente relevante sobre diagnóstico y tratamiento, pero también la información pertinente sobre la fisiopatología y la epidemiología. Con un equilibrio muy conseguido entre conocimientos clásicos y los planteamientos innovadores más recientes, basados en los avances en tecnología molecular.

Consequences of Intracellular Amyloid in Alzheimer’s Disease addresses one of the more currently unresolved aspects confounding Alzheimer’s research, the significance of intraneuronal amyloid. It seeks to explain some of the unresolved questions concerning intracellular amyloid and its origin, entry, and toxicity.

Following up on Dr. D’Andrea’s first book, Bursting Neurons and Fading Memories: An Alternative Hypothesis for the Pathogenesis of Alzheimer’s Disease, this book further examines the Inside-Out or Bursting alternative hypothesis of how amyloid escapes the circulatory system to ultimately enter neurons, also examining whether there is a relationship between intracellular amyloid, amyloid plaques, and cognitive impairment. Through a comprehensive explanation of the currently relevant scientific research on intracellular amyloid compiled in this handy reference, readers will better understand the mechanisms that lead to neuron death.

• Presents the latest research on the significance of intracellular amyloid as it relates to Alzheimer’s
• Addresses crucial questions about intracellular amyloid, including how if forms and enters neurons, its toxicity, if it triggers cell death, and how amyloid plaques are formed
• Examines the potential relationship between intracellular amyloid, plaques, and cognitive impairment in an effort to answer whether Alzheimer’s is initially a problem of amyloid, the neuron, or of the blood-brain barrier
• Seeks to help researchers generate additional alternative therapeutic opportunities to cure Alzheimer’s

Intracellular Parasitic Protozoa introduces the basic structure and classification of intracellular parasitic protozoa and the concept of parasitism.
This book starts by discussing the concept of parasitism and the taxonomic background of various intracellular protozoan organisms. This is followed by a description of the relationships between intracellular protozoan and their host cells. Then, this book discusses the ultrastructure of cells and organisms, emphasizing cell morphology that serves as the primary basis of generalizations of the host cell-parasite relationships. It also presents the intracellular protozoa in several groups according to their probable taxonomic relationships and more obvious morphological similarities. Finally, this text describes protozoan fine structure, along with a brief discussion of their biological aspects.
This book is ideal for researchers, teachers, and students who wish to gain more knowledge in parasitism caused by intracellular protozoa.

Intracellular Transport, Volume 5 brings together a seemingly disparate group of scientists who offer their perspectives on the processes of and mechanisms underlying intracellular transport.
Organized into 14 chapters, this volume begins with a review of some of the viewpoints about membrane structure and the unit membrane concept, including the so-called pauci-molecular theory of cell membrane structure advanced by Danielli and Davson. The next chapters focus on intracellular potentials, the localization of adenine nucleoside phosphatase activity, pinocytosis in amoeba, the brush border of cells, and the transport of gamma-aminobutyric acid. The reader is also introduced to pattern and rhythm; diffusion and reaction coupling; compartmental analysis and residence time distributions; and parametric pumping. The remaining chapters explore intracellular transport fluxes; theoretical aspects of permeability transport; rotating helices and contractile mechanisms; and the movements of cell membranes.
This book is a valuable source of information for cellular biologists concerned with nature's evolved processing plants and engineers involved in the analysis and design of chemical processing plants.