Catálogo de publicaciones

Immune Regulators in Transfer Factor is a collection of papers presented at the Third International Symposium on Transfer Factor held on October 12-14, 1978 at the Wadley Institutes of Molecular Medicine in Dallas, Texas. Contributors focus on immune regulators occurring in transfer factor, a dialyzable component of leukocyte lysates. The isolation and characterization of the immunologically active molecules, as well as tests for in vitro and in vivo, are described.
This volume is organized into five sections encompassing 73 chapters and begins with an overview of animal models used in research on dialyzable leukocyte extracts, their modulation of suppressor activity, effects in mice, and activity and specificity of human and bovine transfer factor. The next section considers in vitro testing, touching on topics such as the quantification and biological assays of transfer factor; the specificity of transfer factor action on macrophage migration; and the effect of transfer factor therapy on antibody-dependent cytotoxic activity in humans. The reader is then introduced to the preparation, purification, and characterization of transfer factor, as well as clinical investigations ranging from phase I studies to randomized controlled trials.
This book will be of interest to scientists and researchers in fields such as molecular medicine, biomedicine, microbiology, immunology, oncology, pathology, and immunotherapy.

Immune Surveillance deals with the issues regarding tumor immunology and surveillance, in which the central theme is all about the life span of the mammalian host that is depleted by the environment with mutagenic agents and solutions.
The book is divided into six chapters. It includes discussions on the organization and modulation of cell membrane receptors, as well as the origin and expression of membrane antigens. It also covers the topics on the triggering mechanisms for and effector mechanisms activated by the cellular recognition. These topics analyze and evaluate alternatives for the recognition and destruction mechanisms in the knowledge of cell cooperation and requirements for immune recognition. A chapter provides discourse on a solution for the paradox of thriving tumors based on the demonstrable in vitro host immunity. Another discusses the generation of antibody diversity and the theory of self-tolerance. The last chapter explains the evaluation of the evidence for immune surveillance.
This reference will be invaluable to those who specialize in immunology.

Immunity to Cancer documents the proceedings of a conference on "Immunity to Cancer" held at Williamsburg, Virginia, September 10-12, 1984. This was the first open conference since the New York Academy of Sciences meeting in 1975 that attempted to address the entire range of topics encompassed by tumor immunology and immunotherapy.
The papers presented in this volume were invited from experts in diverse areas of tumor immunology and closely related subjects. There was an attempt to proceed logically from a consideration of the antigenicity of tumors and the use of monoclonal antibodies to examine specific antigens, to a review of regulatory and effector mechanisms. Immunological approaches to therapy were then considered systematically, both for classical modes of immunotherapy and for the newly expanded categories of biological response modifiers or biomodulators. Also included were papers on vaccination against cancer and on the analogy between the strategies for chemotherapy and immunotherapy.