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An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic building block, the neuron. The third edition of From Molecules to Networks provides the solid foundation of the morphological, biochemical, and biophysical properties of nerve cells. In keeping with previous editions, the unique content focus on cellular and molecular neurobiology and related computational neuroscience is maintained and enhanced.

All chapters have been thoroughly revised for this third edition to reflect the significant advances of the past five years. The new edition expands on the network aspects of cellular neurobiology by adding new coverage of specific research methods (e.g., patch-clamp electrophysiology, including applications for ion channel function and transmitter release; ligand binding; structural methods such as x-ray crystallography).

Written and edited by leading experts in the field, the third edition completely and comprehensively updates all chapters of this unique textbook and insures that all references to primary research represent the latest results.

• The first treatment of cellular and molecular neuroscience that includes an introduction to mathematical modeling and simulation approaches
• 80% updated and new content
• New Chapter on "Biophysics of Voltage-Gated Ion Channels"
• New Chapter on "Synaptic Plasticity"
• Includes a chapter on the Neurobiology of Disease
• Highly referenced, comprehensive and quantitative
• Full color, professional graphics throughout
• All graphics are available in electronic version for teaching purposes

With the appearance of methods for the sequencing of genomes and less expensive next generation sequencing methods, we face rapid advancements of the -omics technologies and plant biology studies: reverse and forward genetics, functional genomics, transcriptomics, proteomics, metabolomics, the movement at distance of effectors and structural biology. From plant genomics to plant biotechnology reviews the recent advancements in the post-genomic era, discussing how different varieties respond to abiotic and biotic stresses, understanding the epigenetic control and epigenetic memory, the roles of non-coding RNAs, applicative uses of RNA silencing and RNA interference in plant physiology and in experimental transgenics and plants modified to specific aims. In the forthcoming years these advancements will support the production of plant varieties better suited to resist biotic and abiotic stresses, for food and non-food applications.

This book covers these issues, showing how such technologies are influencing the plant field in sectors such as the selection of plant varieties and plant breeding, selection of optimum agronomic traits, stress-resistant varieties, improvement of plant fitness, improving crop yield, and non-food applications in the knowledge based bio-economy.

• Discusses a broad range of applications: the examples originate from a variety of sectors (including in field studies, breeding, RNA regulation, pharmaceuticals and biotech) and a variety of scientific areas (such as bioinformatics, -omics sciences, epigenetics, and the agro-industry)
• Provides a unique perspective on work normally performed 'behind closed doors'. As such, it presents an opportunity for those within the field to learn from each other, and for those on the 'outside' to see how different groups have approached key problems
• Highlights the criteria used to compare and assess different approaches to solving problems. Shows the thinking process, practical limitations and any other considerations, aiding in the understanding of a deeper approach

Frontiers in Computational Chemistry, originally published by Bentham and now distributed by Elsevier, presents the latest research findings and methods in the diverse field of computational chemistry, focusing on molecular modeling techniques used in drug discovery and the drug development process. This includes computer-aided molecular design, drug discovery and development, lead generation, lead optimization, database management, computer and molecular graphics, and the development of new computational methods or efficient algorithms for the simulation of chemical phenomena including analyses of biological activity. In Volume 1, the leading researchers in the field have collected eight different perspectives in the application of computational methods towards drug design to provide an up-to-date rendering of the current field. This volume covers a variety of topics from G protein-coupled receptors, to the use of cheminformatics and bioinformatics, computational tools such as Molecular Mechanics Poisson-Boltzmann Surface Area, protein-protein interactions, the use of computational methods on large biological data sets, various computational methods used to identify pharmaceutically relevant targets, and more.

• Brings together a wide range of research into a single collection to help researchers keep up with new methods
• Uniquely focuses on computational chemistry approaches that can accelerate drug design
• Makes a solid connection between experiment and computation and the novel application of computational methods in the fields of biology, chemistry, biochemistry, physics, and biophysics, with particular focus on the integration of computational methods with experimental data

Frontiers in Computational Chemistry, originally published by Bentham and now distributed by Elsevier, presents the latest research findings and methods in the diverse field of computational chemistry, focusing on molecular modeling techniques used in drug discovery and the drug development process. This includes computer-aided molecular design, drug discovery and development, lead generation, lead optimization, database management, computer and molecular graphics, and the development of new computational methods or efficient algorithms for the simulation of chemical phenomena including analyses of biological activity. In Volume 2, the authors continue the compendium with nine additional perspectives in the application of computational methods towards drug design. This volume covers an array of subjects from modern hardware advances that accelerate new antibacterial peptide identification, electronic structure methods that explain how singlet oxygen damages DNA, to QSAR model validation, the application of DFT and DFRT methods on understanding the action of nitrogen mustards, the design of novel prodrugs using molecular mechanics and molecular orbital methods, computational simulations of lipid bilayers, high throughput screening methods, and more.

• Brings together a wide range of research into a single collection to help researchers keep up with new methods
• Uniquely focuses on computational chemistry approaches that can accelerate drug design
• Makes a solid connection between experiment and computation, and the novel application of computational methods in the fields of biology, chemistry, biochemistry, physics, and biophysics

Frontiers in Physicochemical Biology documents the proceedings of an international symposium held in celebration of the 50th anniversary of the Institut de Biologie Physico-Chimique, (Fondation Edmond de Rothschild) in Paris, May 23-27, 1977. The symposium was organized to cover the main topics of modern day molecular biology and biophysics, which are also the major disciplines researched at the Institute.
The contributions made by researchers at the symposium are organized into four parts. Part I contains papers on the physical chemistry of fundamental biomolecules. Part II presents studies on physicochemical aspects of the mechanisms of genetic expression. Part III examines the biochemistry of oxygen and hemoglobin. Part IV deals with the study of organized systems.

Frontiers of Materials Research/Electronic And Optical Materials: Volume I is part of a five-volume compilation of the proceedings of C-MRS International 1990 Conference held in Beijing, China. The said conference discusses the areas of research in materials science.
The book is divided into three parts. Part 1 covers topics involved in the development and progress of materials such as the focused beam ion; intermetallic compounds; polymers; and the application of computers in the field. Part 2 includes studies related to high Tc superconductors such as methods related to the field; the effects of oxygen and partial pressure on the properties of superconducting; and the study of superconductivity and crystallography. Part 3 presents papers related optoelectronic materials and functional crystals, which are mostly about the growth, properties, and uses of the different crystals being studied in each paper.
The text is recommended for scientists and engineers who would like to know more about the field of materials science, especially those who would like to be involved in materials research.