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ISSNs 2380-193X (en línea)
Cobertura temática: Ciencias de la salud - Otras ciencias médicas - Sociología
Cobertura temática: Ciencias médicas y de la salud - Ciencias de la salud
Cobertura temática: Ciencias naturales - Ciencias físicas - Ciencias sociales - Sociología
978-0-12-405944-3 (en línea)
Cobertura temática: Ciencias de la salud - Derecho
Transgenerational Epigenetics provides a comprehensive analysis of the inheritance of epigenetic phenomena between generations. Recent research points to the existence of biological phenomena that are controlled not through gene mutations, but rather through reversible and heritable epigenetic processes.
Epidemiological studies have suggested that environmental factors may be heritable. In fact, environmental factors often play a role in transgenerational epigenetics, which may have selective or adverse effects on the offspring. This epigenetic information can be transferred through a number of mechanisms including DNA methylation, histone modifications or RNA and the effects can persist for multiple generations.
This book examines the evolution of epigenetic inheritance, its expression in animal and plant models, and how human diseases, such as metabolic disorders and cardiovascular diseases, appear to be affected by transgenerational epigenetic inheritance. It discusses clinical interventions in transgenerational epigenetic inheritance that may be on the horizon to help prevent diseases before the offspring are born, or to reduce the severity of diseases at the very earliest stages of development in utero, and current controversies in this area of study, as well as future directions for research.
ISBNs: 978-1-58829-507-1 (impreso) 978-1-59745-058-4 (en línea)
Cobertura temática: Medicina básica
978-0-12-410490-7 (en línea)
Cobertura temática: Ciencias biológicas - Ciencias de la salud - Artes
Transgenic animal technologies and the ability to introduce functional genes into animals have revolutionized our ability to address complex biomedical and biological questions. This well-illustrated handbook covers the technical aspects of gene transfer — from molecular methods to whole animal considerations — for important laboratory and domestic animal species. It describes methodologies as employed by leading laboratories and is a key resource for researchers, as well as a tool for training technicians and students. This second edition incorporates updates on a variety of genetic engineering technologies ranging from microinjection and ES cell transfer to nuclear transfer in a broad range of animal modeling systems.
Cobertura temática: Ciencias naturales - Ciencias biológicas
ISBNs: 978-3-540-36751-2 (impreso) 978-3-540-36752-9 (en línea)
Cobertura temática: Ciencias biológicas - Agricultura, silvicultura y pesca
ISBNs: 978-3-540-49160-6 (impreso) 978-3-540-49161-3 (en línea)
ISBNs: 978-3-540-71710-2 (impreso) 978-3-540-71711-9 (en línea)