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The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment

978-0-12-417144-2 (en línea)

Disponibilidad

Institución detectada	Año de publicación	Navegá	Descargá	Solicitá
No detectada	2015	ScienceDirect

Cobertura temática: Medicina básica

Resumen disponible

The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal welfare legislation, safety assessment of biologics and small molecules, immunotoxicology and much more, this book provides scientific and technical insights to help you safely and successfully use nonhuman primates in pharmaceutical toxicity testing. A comprehensive yet practical guide, this book is intended for new researchers or practicing toxicologists, toxicologic pathologists and pharmaceutical scientists working with nonhuman primates, as well as graduate students preparing for careers in this area.

Covers important topics such as species selection, study design, experimental methodologies, animal welfare and the 3Rs (Replace, Refine and Reduce), social housing, regulatory guidelines, comparative physiology, reproductive biology, genetic polymorphisms and more
Includes practical examples on techniques and methods to guide your daily practice
Offers a companion website with high-quality color illustrations, reference values for safety assessment and additional practical information such as study design considerations, techniques and procedures and dosing and sampling volumes

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The Nonlinear Schrödinger Equation

Disponibilidad

Institución detectada	Año de publicación	Navegá	Descargá	Solicitá
No requiere		Directory of Open access Books

Cobertura temática: Ciencias naturales - Ciencias físicas

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The Nonlinear Theory of Elastic Shells: One Spatial Dimension

978-0-12-447940-1 (en línea)

Disponibilidad

Institución detectada	Año de publicación	Navegá	Descargá	Solicitá
No detectada	1988	ScienceDirect

Cobertura temática: Ciencias biológicas - Ingeniería de los materiales - Agricultura, silvicultura y pesca

Resumen disponible

The Nonlinear Theory of Elastic Shells: One Spatial Dimension presents the foundation for the nonlinear theory of thermoelastic shells undergoing large strains and large rotations. This book discusses several relatively simple equations for practical application.
Organized into six chapters, this book starts with an overview of the description of nonlinear elastic shell. This text then discusses the foundation of three-dimensional continuum mechanics that are relevant to the shell theory approach. Other chapters cover several topics, including birods, beamshells, and axishells that begins with a derivation of the equations of motion by a descent from the equations of balance of linear and rotational momentum of a three-dimensional material continuum. This book discusses as well the approach to deriving complete field equations for one- or two-dimensional continua from the integral equations of motion and thermodynamics of a three-dimensional continuum. The final chapter deals with the analysis of unishells.
This book is a valuable resource for physicists, mathematicians, and scientists.

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