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Molecular Diagnostics: Techniques and Applications for the Clinical Laboratory

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978-0-12-369428-7 (en línea)

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Institución detectada Año de publicación Navegá Descargá Solicitá
No detectada 2010 ScienceDirect

Cobertura temática: Ciencias biológicas - Ciencias de la salud - Ciencias agrícolas y veterinarias  

Advances in genomic and proteomic profiling of disease have transformed the field of molecular diagnostics, thus leading the way for a major revolution in clinical practice. While the range of tests for disease detection and staging is rapidly expanding, many physicians lack the knowledge required to determine which tests to order and how to interpret results. This handbook provides a complete guide to the use and interpretation of molecular testing in the clinical arena. No other available resource offers this emphasis, comprehensive scope, and practical utility in the clinical setting.

* Serves as the definitivereference for molecular pathologists worldwide

* Covers a variety of molecular techniques including next generation sequencing, tumor somatic cell genotyping, infectious and genetic disease tecting, and pharmacogenetics

* Discusses in the detail issues concerning quality assurance, regulation, ethics, and future directions for the science


Molecular Diagnostics

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978-0-12-374537-8 (en línea)

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No detectada 2010 ScienceDirect

Cobertura temática: Ciencias biológicas - Ciencias de la salud - Ciencias agrícolas y veterinarias  

KEY FEATURES:
• Contains state-of-the-art techniques for the detection of the underlying genetic heterogeneity leading to inherited disorders
• Includes in-depth discussion of ethical and safety considerations
• Identifies genetically modified organisms (GMOs)
• Covers forensic analysis and everyday issues in a diagnostic laboratory

DESCRIPTION:
The2e of Molecular Diagnostics, the only book dealing with diagnosis on a molecular level, discusses current molecular biological techniques used to identify the underlying molecular defects in inherited disease. The book delves further into the principle and brief description of the technique, followed by examples from the authors' own expertise. Contributors to the 2e are well-known experts in their field, and derive from a variety of disciplines, to ensure breadth and depth of coverage. Molecular Diagnostics, 2e , is a needed resource for graduate students, researchers, physicians and practicing scientists in molecular genetics and professionals from similar backgrounds working in diagnostic laboratories in academia or industry, as well as academic institutions and hospital libraries.

Key Features:
*Deals exclusively with the currently used molecular biology techniques to identify the underlying molecular defect of inherited diseases

*Includes pharmacogenetics and pharmacogenomics relating to new cancer therapies

*Provies a comprehensive guide through emerging concepts and demonstrates how the available mutation screening technology can be implemented in diagnostic laboratories and provide better healthcare

Molecular Diagnostics and Treatment of Pancreatic Cancer: Systems and Network Biology Approaches

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978-0-12-408103-1 (en línea)

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Institución detectada Año de publicación Navegá Descargá Solicitá
No detectada 2014 ScienceDirect

Cobertura temática: Ciencias biológicas - Ciencias de la salud - Ciencias agrícolas y veterinarias  

Molecular Diagnostics and Treatment of Pancreatic Cancer describes the different emerging applications of systems biology and how it is shaping modern pancreatic cancer research. This book begins by introducing the current state of the art knowledge, trends in diagnostics, progress in disease model systems as well as new treatment and palliative care strategies in pancreatic cancer. Specific sections are dedicated to enlighten the readers to newer discoveries that have emerged from gene expression profiling, proteomics, metabolomics and systems level analyses of pancreatic cancer datasets. First of a kind and novel network strategies to understand oncogenic Kras signaling in pancreatic tumors are presented. The attempts to computationally model and prioritize microRNAs that cause pancreatic cancer resistance are also highlighted.

Addressing this important area, Molecular Diagnostics and Treatment of Pancreatic Cancer provides insights into important network evaluation methodologies related to pancreatic cancer related microRNAs targetome. There are dedicated chapters on critical aspects of the evolving yet controversial field of pancreatic cancer stems cells. The work concludes by discussing the applications of network sciences in pancreatic cancer drug discovery and clinical trial design.

  • Encompasses discussion of innovative tools including expression signatures in cell lines, 3D models, animal xenograft models, primary models and patient derived samples, aiding subversion of traditional biology paradigms, and enhancing comprehension across conventional length and temporal scales
  • Coverage includes novel applications in targeted drugs, polypharmacology, network pharmacology and other related drug development arenas – helping researchers in pancreatic cancer drug discovery
  • Summarizes many relevant computational and clinical references from fast-evolving literature
  • Comprehensive glossary helps newer readers understand technical terms and specialized nomenclature

Molecular Diversity

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ISSNs 1381-1991 (impreso) 1573-501X (en línea)

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Institución detectada Período Navegá Descargá Solicitá
No detectada desde mar. 1997 / hasta dic. 2020 SpringerLink

Cobertura temática: Ciencias de la computación e información - Ciencias químicas - Ciencias biológicas - Ciencias médicas y de la salud - Medicina básica  


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Molecular Docking

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Cobertura temática: Ciencias biológicas  


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Molecular Docking: Recent Advances

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Cobertura temática: Ciencias naturales - Ciencias biológicas  


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Molecular Dynamics Simulation

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ISBNs: 9783906980652 (impreso) 9783906980669 (en línea)

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No requiere 2014 Directory of Open access Books acceso abierto

Cobertura temática: Ciencias biológicas - Medicina básica - Medicina clínica - Ciencias de la salud - Otras ciencias sociales  


Molecular Ecology

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ISSNs 0962-1083 (impreso) 1365-294X (en línea)

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Institución detectada Período Navegá Descargá Solicitá
No detectada desde ene. 1992 / hasta dic. 2023 Wiley Online Library

Cobertura temática: Ciencias biológicas  


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Molecular Ecology and Genetic Diversity of the Roseobacter Clade

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Institución detectada Año de publicación Navegá Descargá Solicitá
No requiere Directory of Open access Books acceso abierto

Cobertura temática: Ciencias biológicas  


Molecular Ecology Notes

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ISSNs 1471-8278 (impreso) 1471-8286 (en línea)

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Institución detectada Período Navegá Descargá Solicitá
No detectada desde ene. 2001 / hasta dic. 2023 Wiley Online Library

Cobertura temática: Ciencias biológicas