Catálogo de publicaciones - tesis
Título de Acceso Abierto
Design, simulation, fabrication and characterization of mass microsensors embeddable to an implantable microvalve for glaucoma treatment
Martín Ángel Zalazar Fabio Ariel Guarnieri Oscar De Sanctis Alberto Cardona Marcelo Javier Otero
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Resumen/Descripción – provisto por el repositorio digital
The main research of the Group of BioMEMS is the implantable microvalve for controlling the intraocular pressure in patients with glaucoma. Glaucoma is a disease that affects tens of millions of people around the world. The development of Micro ElectroMechanical Systems and the generation of new materials allow the development of implantable micro-devices with improved biocompatibility. The knowledge of biomolecules associated with the glaucoma pathology will increase the effectiveness of the implant. In this sense, a mass microsensor capable of sensing biomolecules is desirable; also the microsensor has to be capable of being integrated to the implantable microvalve. This thesis was focused on the design, simulation, fabrication and characterization of Micro ElectroMechanical Systems -based mass microsensors for the detection of biomolecules. It starts with a modeling and simulation chapter where different types of microsensors were developed by using piezoelectric resonators, and follows a fabrication and characterization chapter. Regarding the biocompatibility, Ultrananocrystalline diamond and Parylene were used as structural materials; as piezoelectric materials, quartz, polyvinylidene fluoride and Aluminium Nitride were used. The parameters of the resonators were extracted by using 3D Finite Element Method models and experimental results; values were adjusted to fit the simulated frequency response with the experimental one. Ultrananocrystalline diamond films used as substrate, yielded a highly oriented (002) Aluminium Nitride films even as thin as 80 nanometers; it exhibited a piezoelectric coefficient of about 5.3 picometer per volt, one of the highest demonstrated today.Palabras clave – provistas por el repositorio digital
Micro electro mechanical systems; Quartz crystal microbalance; Finite element method; Numerical simulation; Resonador piezoeléctrico; Biosensor; Sistema microelectromecánico; Microbalanza de cristal de cuarzo; Método de elementos finitos; Simulación numérica; Piezoelectric resonator
Disponibilidad
| Institución detectada | Año de publicación | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No requiere | 2016 | Biblioteca Virtual de la Universidad Nacional del Litoral (SNRD) |
|
Información
Tipo de recurso:
tesis
Idiomas de la publicación
- inglés
País de edición
Argentina
Fecha de publicación
2016-10-15
