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Journal of Chromatography. B

Resumen/Descripción – provisto por la editorial en inglés
The Journal of Chromatography B publishes papers on developments in separation science relevant to biology and biomedical research including both fundamental advances and applications.

Analytical techniques which may be considered include the various facets of chromatography, electrophoresis and related methods, affinity and immunoaffinity-based methodologies, hyphenated and other multi-dimensional techniques, and microanalytical approaches. The journal also considers articles reporting developments in sample preparation, detection techniques including mass spectrometry, and data handling and analysis.

Developments related to preparative separations for the isolation and purification of components of biological systems may be published, including chromatographic and electrophoretic methods, affinity separations, field flow fractionation and other preparative approaches.

Applications to the analysis of biological systems and samples will be considered when the analytical science contains a significant element of novelty, e.g. a new approach to the separation of a compound, novel combination of analytical techniques, or significantly improved analytical performance. Areas to be considered include:
• The qualitative and quantitative analysis of biopolymers including proteins, peptides and their post-translational modifications as well as nucleic acids and glycans • The comparative analysis of biological systems using proteomics, genomics, metabonomics and other "omics" approaches
• Clinical analysis, pharmacokinetics, metabolism, therapeutic drug monitoring, toxicological analysis, doping analysis, veterinary applications, analysis of environmental contaminants in biological systems
• The screening and profiling of body fluids, tissues, cells, biological matrices and systems, analysis of endogenous compounds, biomarkers
• Identification of new bioactive compounds

Applications which utilize published or commercial analytical or preparative protocols with little or no modification or where the results of the application rather than the analytical methodology comprise the major element of novelty of the manuscript should be directed to more specialized journals. Modifications to a previously published method may be considered for a short communication in cases where the improvement in performance is significant. Reports of analytical methods for compounds in early pharmaceutical development often lack general interest and will not be published unless the authors can demonstrate the broader significance of the methodology involved. Quality control analyses of bulk drugs, natural products or pharmaceutical formulations are not within scope.
Palabras clave – provistas por la editorial

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Disponibilidad
Institución detectada Período Navegá Descargá Solicitá
No detectada desde ene. 2002 / hasta dic. 2023 ScienceDirect

Información

Tipo de recurso:

revistas

ISSN impreso

1570-0232

ISSN electrónico

1873-376X

Editor responsable

Elsevier

País de edición

Países Bajos

Fecha de publicación

Tabla de contenidos

Efficient HPLC method for the determination of nicarbazin, as dinitrocarbanilide in broiler liver

Emiliana Capurro; Martin Danaher; Aniello Anastasio; Maria Luisa Cortesi; Michael O’Keeffe

Palabras clave: Analytical Chemistry; Clinical Biochemistry; Cell Biology; Biochemistry; General Medicine.

Pp. 154-159

Determination of glyphosate, glyphosate metabolites, and glufosinate in human serum by gas chromatography–mass spectrometry

M MOTOJYUKU; T SAITO; K AKIEDA; H OTSUKA; I YAMAMOTO; S INOKUCHI

Palabras clave: Analytical Chemistry; Clinical Biochemistry; Cell Biology; Biochemistry; General Medicine.

Pp. 509-514

Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoids in cannabis plant material

Benjamin De Backer; Benjamin Debrus; Pierre Lebrun; Laetitia Theunis; Nathalie Dubois; Lies Decock; Alain Verstraete; Philippe Hubert; Corinne Charlier

Pp. 4115-4124

Internal standards in the quantitative determination of protein biopharmaceuticals using liquid chromatography coupled to mass spectrometry

Kees J. Bronsema; Rainer Bischoff; Nico C. van de Merbel

Pp. 1-14

A determinative and confirmatory method for ceftiofur metabolite desfuroylceftiofur cysteine disulfide in bovine kidney by LC–MS/MS

Shixia Feng; Chaitali Chattopadhaya; Philip Kijak; Oscar A. Chiesa; Elizabeth A. Tall

Palabras clave: Cell Biology; Clinical Biochemistry; Biochemistry; General Medicine; Analytical Chemistry.

Pp. 62-68

Simultaneous determination of eight corticosteroids in bovine tissues using liquid chromatography–tandem mass spectrometry

Ádám Tölgyesi; Virender K. Sharma; Szabolcs Fekete; Dóra Lukonics; Jenő Fekete

Pp. 75-84

Validated UPLC–MS/MS method for simultaneous determination of simvastatin, simvastatin hydroxy acid and berberine in rat plasma: Application to the drug–drug pharmacokinetic interaction study of simvastatin combined with berberine after oral administratio

Mei Liu; Xianying Su; Guofei Li; Guilian Zhao; Limei Zhao

Palabras clave: Cell Biology; Clinical Biochemistry; Biochemistry; General Medicine; Analytical Chemistry.

Pp. 8-15

Measurement of serum steroid profiles by HPLC-tandem mass spectrometry

Dmitrii Olisov; Kyunghoon Lee; Sun-Hee Jun; Sang Hoon Song; Jae Hyun Kim; Young Ah Lee; Choong Ho Shin; Junghan Song

Palabras clave: Analytical Chemistry; Clinical Biochemistry; Cell Biology; Biochemistry; General Medicine.

Pp. 1-9

Stability characteristics of cannabidiol for the design of pharmacological, biochemical and pharmaceutical studies

A.I. Fraguas-Sánchez; A. Fernández-Carballido; C. Martin-Sabroso; A.I. Torres-Suárez

Pp. 122188