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Journal of Bioactive and Compatible Polymers

Resumen/Descripción – provisto por la editorial en inglés
The Journal of Bioactive and Compatible Polymers provides biomedical polymer scientists and researchers throughout the world with current frontier research advances in the field. Coverage includes polymeric scaffolds for tissue engineering and tissue regeneration, polymeric drugs and pro-drug systems, drug delivery and targeted delivery systems, biosensors and stimuli-sensitive biosystems, modeling and modification of enzyme sensitive polymer systems, biorelated polymers with unique properties and bioapplications.
Palabras clave – provistas por la editorial

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Disponibilidad
Institución detectada Período Navegá Descargá Solicitá
No detectada desde ene. 1999 / hasta dic. 2023 SAGE Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0883-9115

ISSN electrónico

1530-8030

Editor responsable

SAGE Publishing (SAGE)

País de edición

Estados Unidos

Fecha de publicación

Tabla de contenidos

Production of alginate films containing Hypericum perforatum extract as an antibacterial and antioxidant wound dressing material

Betül MutluORCID; Fatih Erci; Rabia Çakir Koç

<jats:p> The incorporation of herbal extracts in wound dressing materials is an important concept that has been researched recently. In this study, alginate films incorporated in the various ratio (0.25–1% v/v) of Hypericum perforatum extract (HPE) for potential applications of wound dressing were successfully prepared by solvent-casting method. The obtained films were examined for cytotoxicity, in vitro wound healing potential, swelling behavior, antioxidant, and antibacterial properties. When compared to the alginate film (Al) alone, HPE incorporated alginate films (HPE/Al) exhibit improved antioxidant properties according to the results of CUPRAC assay and antioxidant activity increases with the rate of HPE. Also, HPE/Al films exhibited antibacterial activity against E. coli and S. aureus, and addition with the HPE extract into films significantly increased the antibacterial activity against S. aureus. All film samples had no cytotoxic effects on fibroblast cell line and HPE/Al films showed a proliferative effect with high extract concentrations (1%) compared to extract free-films. Also, scratch assay results show that films containing 0.5% (v/v) HPE may have a positive effect on wound healing. The results have shown that the newly developed HPE incorporated alginate films are a candidate as antibacterial, and antioxidant wound dressing for use on burn or excision wounds. </jats:p>

Palabras clave: Materials Chemistry; Polymers and Plastics; Biomaterials; Bioengineering.

Pp. 134-148