Catálogo de publicaciones - revistas
Life Sciences
Resumen/Descripción – provisto por la editorial en inglés
Life Sciences is an international journal publishing articles that emphasize the molecular, cellular, and functional basis of therapy. The journal emphasizes the understanding of mechanism that is relevant to all aspects of human disease and translation to patients. All articles are rigorously reviewed.The Journal favors publication of full-length papers where modern scientific technologies are used to explain molecular, cellular and physiological mechanisms. Articles that merely report observations are rarely accepted. Recommendations from the Declaration of Helsinki or NIH guidelines for care and use of laboratory animals must be adhered to. Articles should be written at a level accessible to readers who are non-specialists in the topic of the article themselves, but who are interested in the research. The Journal welcomes reviews on topics of wide interest to investigators in the life sciences. We particularly encourage submission of brief, focused reviews containing high-quality artwork and require the use of mechanistic summary diagrams.
Manuscripts should present novel preclinical findings addressing questions of biological significance to human disease. Studies that fail to do so may be rejected without review. Quantitative conclusions must be based on truly quantitative methods. Life Sciences does not publish work on the actions of biological extracts of unknown chemical composition. Compounds studied must be of known chemical structure and concentration. The study must be reproducible; materials used must be available to other researchers so they can repeat the experiment. Clinical studies may be considered if they expand understanding of mechanism, but the journal does not encourage clinical trial reports.
Four common reasons for rejection include: out of scope (the manuscript does not conform to the goal of identification of mechanisms related to therapy for human disease); too preliminary (manuscript is based on a limited amount of experimental data diminishing significance); lack of novelty (manuscript is well done but does not address a significant question); unidentified structure (actions of biological extracts of unknown chemical composition).
Palabras clave – provistas por la editorial
No disponibles.
Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde ene. 1962 / hasta dic. 2023 | ScienceDirect |
Información
Tipo de recurso:
revistas
ISSN impreso
0024-3205
ISSN electrónico
1879-0631
Editor responsable
Elsevier
País de edición
Reino Unido
Fecha de publicación
1973-
Cobertura temática
Tabla de contenidos
Targeting eosinophils in respiratory diseases: Biological axis, emerging therapeutics and treatment modalities
Li-Yen Lee; Geena Suet Yin Hew; Meenu Mehta; Shakti D. Shukla; Saurabh Satija; Navneet Khurana; Krishnan Anand; Harish Dureja; Sachin Kumar Singh; Vijay Mishra; Pankaj Kumar Singh; Monica Gulati; Parteek Prasher; Alaa A.A. Aljabali; Murtaza M. Tambuwala; Lakshmi Thangavelu; Jithendra Panneerselvam; Gaurav Gupta; Flavia C. Zacconi; Madhur Shastri; Niraj Kumar Jha; Dikaia Xenaki; Ronan MacLoughlin; Brian G. Oliver; Dinesh Kumar Chellappan; Kamal Dua
Palabras clave: General Pharmacology, Toxicology and Pharmaceutics; General Biochemistry, Genetics and Molecular Biology; General Medicine.
Pp. 118973
Identification of novel drug resistance mechanisms by genomic and transcriptomic profiling of glioblastoma cells with mutation-activated EGFR
Onat Kadioglu; Mohamed E.M. Saeed; Nuha Mahmoud; Shaymaa Azawi; Kristin Mrasek; Thomas Liehr; Thomas Efferth
Palabras clave: General Pharmacology, Toxicology and Pharmaceutics; General Biochemistry, Genetics and Molecular Biology; General Medicine.
Pp. 119601
Yacon-based product improves intestinal hypertrophy and modulates the production of glucagon-like peptide-1 in postmenopausal experimental model
Joice de Fátima Laureano Martins; Thaiany Goulart Souza-Silva; Hudsara Aparecida de Almeida Paula; Viviane da Cruz Rafael; Sirlene Souza Rodrigues Sartori; Célia Lúcia de Luces Fortes Ferreira
Palabras clave: General Pharmacology, Toxicology and Pharmaceutics; General Biochemistry, Genetics and Molecular Biology; General Medicine.
Pp. 120245
Effect of cannabidiol on apoptosis and cellular interferon and interferon-stimulated gene responses to the SARS-CoV-2 genes ORF8, ORF10 and M protein
Maria Fernanda Fernandes; John Zewen Chan; Chia Chun Joey Hung; Michelle Victoria Tomczewski; Robin Elaine Duncan
Pp. 120624
Empagliflozin attenuates trastuzumab-induced cardiotoxicity through suppression of DNA damage and ferroptosis
Jie Min; Lin Wu; Yandong Liu; Guoliang Song; Qinqin Deng; Wei Jin; Wei Yu; Miyesaier Abudureyimu; Zhaohui Pei; Jun Ren
Palabras clave: General Pharmacology, Toxicology and Pharmaceutics; General Biochemistry, Genetics and Molecular Biology; General Medicine.
Pp. 121207
Contribution of the opioid system to depression and to the therapeutic effects of classical antidepressants and ketamine
Miroslav Adzic; Iva Lukic; Milos Mitic; Emilija Glavonic; Nina Dragicevic; Sanja Ivkovic
Palabras clave: General Pharmacology, Toxicology and Pharmaceutics; General Biochemistry, Genetics and Molecular Biology; General Medicine.
Pp. 121803