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Journal of Internal Medicine

Resumen/Descripción – provisto por la editorial en inglés
Journal of Internal Medicine (JIM), with its International Advisory Board, has developed into a highly successful journal since it was launched in its revised form in 1989. JIM publishes original clinical work within the broad field of general and internal medicine and its sub-specialties. It features original articles, reviews, and case reports. JIM also supports and organizes scientific meetings in the form of symposia within the scope of the journal.
Palabras clave – provistas por la editorial

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Disponibilidad
Institución detectada Período Navegá Descargá Solicitá
No detectada desde ene. 1863 / hasta dic. 2023 Wiley Online Library

Información

Tipo de recurso:

revistas

ISSN impreso

0954-6820

ISSN electrónico

1365-2796

Editor responsable

John Wiley & Sons, Inc. (WILEY)

País de edición

Reino Unido

Fecha de publicación

Cobertura temática

medicina-clinica

Medicina clínica

Tabla de contenidos

doi: 10.1111/j.0954-6820.1950.tb10101.x

Immunological Analysis of Diphtheria Antigens by the Gel Diffusion Method

ÖRJAN OUCHTERLONY; HANS ERICSSON; CAROLA NEUMÜLLER

Palabras clave: Internal Medicine.

Pp. 76-79

doi: 10.1111/joim.13575

Efficacy and safety of thrombolytic therapy for portal venous system thrombosis: A systematic review and meta‐analysis

Fangbo Gao; Le Wang; Jiahui Pan; Yuhang Yin; Jing Wang; Xiangbo Xu; Shixue Xu; Andrea MancusoORCID; Xingshun QiORCID

<jats:title>Abstract</jats:title><jats:sec><jats:title>Background and aims</jats:title><jats:p>The role of thrombolytic therapy in patients with portal venous system thrombosis (PVST) remains ambiguous. This study aimed to systematically collect available evidence and evaluate the efficacy and safety of thrombolysis for PVST.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Eligible studies were searched via PubMed, EMBASE, and Cochrane Library databases. Among the cohort studies, meta‐analyses were performed to assess the outcomes of PVST patients receiving thrombolysis. Pooled proportions were calculated. Among the case reports and case series, logistic regression analyses were performed to identify the risk factors for outcomes of PVST patients receiving thrombolysis. Odds ratios (ORs) were calculated.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Among the 2134 papers initially identified, 29 cohort studies and 131 case reports or case series were included. Based on the cohort studies, the pooled rates of overall response to thrombolytic therapy, complete recanalization of PVST, bleeding events during thrombolysis, further bowel resection, thrombosis recurrence, and 30‐day mortality were 93%, 58%, 18%, 3%, 1%, and 4%, respectively. Based on the case reports and case series, acute pancreatitis (OR = 0.084), history of liver transplantation (OR = 13.346), and interval between onset of symptoms and initiation of thrombolysis ≤14 days (OR = 3.105) were significantly associated with complete recanalization of PVST; acute pancreatitis (OR = 6.556) was significantly associated with further bowel resection; but no factors associated with the overall response to thrombolytic therapy, bleeding events during thrombolysis, thrombosis recurrence, and 30‐day mortality were identified or could be calculated.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>Early initiation of thrombolysis should be effective for the treatment of PVST. But its benefits for PVST secondary to acute pancreatitis are weakened.</jats:p></jats:sec>

Pp. 212-227