Catálogo de publicaciones - libros
Köhler's Invention
Klaus Eichmann
Resumen/Descripción – provisto por la editorial
No disponible.
Palabras clave – provistas por la editorial
Immunology; Biomedicine general
Disponibilidad
Institución detectada | Año de publicación | Navegá | Descargá | Solicitá |
---|---|---|---|---|
No detectada | 2005 | SpringerLink |
Información
Tipo de recurso:
libros
ISBN impreso
978-3-7643-7173-9
ISBN electrónico
978-3-7643-7413-6
Editor responsable
Springer Nature
País de edición
Reino Unido
Fecha de publicación
2005
Información sobre derechos de publicación
© Birkhäuser Verlag 2005
Cobertura temática
Tabla de contenidos
A short history of the antibody problem
Klaus Eichmann
Integer Linear Programs are widely used in areas such as routing problems, scheduling analysis and optimization, logic synthesis, and partitioning problems. As many of these problems have a Boolean nature, i.e., the variables are restricted to 0 and 1, so called have been proposed. They are mostly based on SAT solvers which took continuous improvements over the past years. However, Pseudo-Boolean solvers are only able to optimize a single linear function while fulfilling several constraints. Unfortunately many real-world optimization problems have multiple objective functions which are often conflicting and have to be optimized simultaneously, resulting in general in a set of optimal solutions. As a consequence, a single-objective Pseudo-Boolean solver will not be able to find this set of optimal solutions. As a remedy, we propose three different algorithms for solving multi-objective Pseudo-Boolean problems. Our experimental results will show the applicability of these algorithms on the basis of several test cases.
Part I - The time before | Pp. 3-16
The immunological scene around Köhler
Klaus Eichmann
Integer Linear Programs are widely used in areas such as routing problems, scheduling analysis and optimization, logic synthesis, and partitioning problems. As many of these problems have a Boolean nature, i.e., the variables are restricted to 0 and 1, so called have been proposed. They are mostly based on SAT solvers which took continuous improvements over the past years. However, Pseudo-Boolean solvers are only able to optimize a single linear function while fulfilling several constraints. Unfortunately many real-world optimization problems have multiple objective functions which are often conflicting and have to be optimized simultaneously, resulting in general in a set of optimal solutions. As a consequence, a single-objective Pseudo-Boolean solver will not be able to find this set of optimal solutions. As a remedy, we propose three different algorithms for solving multi-objective Pseudo-Boolean problems. Our experimental results will show the applicability of these algorithms on the basis of several test cases.
Part I - The time before | Pp. 17-28
Köhler’s entry into science
Klaus Eichmann
Integer Linear Programs are widely used in areas such as routing problems, scheduling analysis and optimization, logic synthesis, and partitioning problems. As many of these problems have a Boolean nature, i.e., the variables are restricted to 0 and 1, so called have been proposed. They are mostly based on SAT solvers which took continuous improvements over the past years. However, Pseudo-Boolean solvers are only able to optimize a single linear function while fulfilling several constraints. Unfortunately many real-world optimization problems have multiple objective functions which are often conflicting and have to be optimized simultaneously, resulting in general in a set of optimal solutions. As a consequence, a single-objective Pseudo-Boolean solver will not be able to find this set of optimal solutions. As a remedy, we propose three different algorithms for solving multi-objective Pseudo-Boolean problems. Our experimental results will show the applicability of these algorithms on the basis of several test cases.
Part I - The time before | Pp. 29-37
The quest for monoclonal antibodies
Klaus Eichmann
Integer Linear Programs are widely used in areas such as routing problems, scheduling analysis and optimization, logic synthesis, and partitioning problems. As many of these problems have a Boolean nature, i.e., the variables are restricted to 0 and 1, so called have been proposed. They are mostly based on SAT solvers which took continuous improvements over the past years. However, Pseudo-Boolean solvers are only able to optimize a single linear function while fulfilling several constraints. Unfortunately many real-world optimization problems have multiple objective functions which are often conflicting and have to be optimized simultaneously, resulting in general in a set of optimal solutions. As a consequence, a single-objective Pseudo-Boolean solver will not be able to find this set of optimal solutions. As a remedy, we propose three different algorithms for solving multi-objective Pseudo-Boolean problems. Our experimental results will show the applicability of these algorithms on the basis of several test cases.
Part I - The time before | Pp. 38-48
Cell fusion
Klaus Eichmann
Integer Linear Programs are widely used in areas such as routing problems, scheduling analysis and optimization, logic synthesis, and partitioning problems. As many of these problems have a Boolean nature, i.e., the variables are restricted to 0 and 1, so called have been proposed. They are mostly based on SAT solvers which took continuous improvements over the past years. However, Pseudo-Boolean solvers are only able to optimize a single linear function while fulfilling several constraints. Unfortunately many real-world optimization problems have multiple objective functions which are often conflicting and have to be optimized simultaneously, resulting in general in a set of optimal solutions. As a consequence, a single-objective Pseudo-Boolean solver will not be able to find this set of optimal solutions. As a remedy, we propose three different algorithms for solving multi-objective Pseudo-Boolean problems. Our experimental results will show the applicability of these algorithms on the basis of several test cases.
Part I - The time before | Pp. 49-56
Köhler in Cambridge
Klaus Eichmann
Integer Linear Programs are widely used in areas such as routing problems, scheduling analysis and optimization, logic synthesis, and partitioning problems. As many of these problems have a Boolean nature, i.e., the variables are restricted to 0 and 1, so called have been proposed. They are mostly based on SAT solvers which took continuous improvements over the past years. However, Pseudo-Boolean solvers are only able to optimize a single linear function while fulfilling several constraints. Unfortunately many real-world optimization problems have multiple objective functions which are often conflicting and have to be optimized simultaneously, resulting in general in a set of optimal solutions. As a consequence, a single-objective Pseudo-Boolean solver will not be able to find this set of optimal solutions. As a remedy, we propose three different algorithms for solving multi-objective Pseudo-Boolean problems. Our experimental results will show the applicability of these algorithms on the basis of several test cases.
Part I - The time before | Pp. 57-78
Back in Basel
Klaus Eichmann
Integer Linear Programs are widely used in areas such as routing problems, scheduling analysis and optimization, logic synthesis, and partitioning problems. As many of these problems have a Boolean nature, i.e., the variables are restricted to 0 and 1, so called have been proposed. They are mostly based on SAT solvers which took continuous improvements over the past years. However, Pseudo-Boolean solvers are only able to optimize a single linear function while fulfilling several constraints. Unfortunately many real-world optimization problems have multiple objective functions which are often conflicting and have to be optimized simultaneously, resulting in general in a set of optimal solutions. As a consequence, a single-objective Pseudo-Boolean solver will not be able to find this set of optimal solutions. As a remedy, we propose three different algorithms for solving multi-objective Pseudo-Boolean problems. Our experimental results will show the applicability of these algorithms on the basis of several test cases.
Part I - The time before | Pp. 79-89
The patent disaster
Klaus Eichmann
Integer Linear Programs are widely used in areas such as routing problems, scheduling analysis and optimization, logic synthesis, and partitioning problems. As many of these problems have a Boolean nature, i.e., the variables are restricted to 0 and 1, so called have been proposed. They are mostly based on SAT solvers which took continuous improvements over the past years. However, Pseudo-Boolean solvers are only able to optimize a single linear function while fulfilling several constraints. Unfortunately many real-world optimization problems have multiple objective functions which are often conflicting and have to be optimized simultaneously, resulting in general in a set of optimal solutions. As a consequence, a single-objective Pseudo-Boolean solver will not be able to find this set of optimal solutions. As a remedy, we propose three different algorithms for solving multi-objective Pseudo-Boolean problems. Our experimental results will show the applicability of these algorithms on the basis of several test cases.
Part I - The time before | Pp. 90-98
The Max-Planck-Institute of Immunobiology
Klaus Eichmann
Integer Linear Programs are widely used in areas such as routing problems, scheduling analysis and optimization, logic synthesis, and partitioning problems. As many of these problems have a Boolean nature, i.e., the variables are restricted to 0 and 1, so called have been proposed. They are mostly based on SAT solvers which took continuous improvements over the past years. However, Pseudo-Boolean solvers are only able to optimize a single linear function while fulfilling several constraints. Unfortunately many real-world optimization problems have multiple objective functions which are often conflicting and have to be optimized simultaneously, resulting in general in a set of optimal solutions. As a consequence, a single-objective Pseudo-Boolean solver will not be able to find this set of optimal solutions. As a remedy, we propose three different algorithms for solving multi-objective Pseudo-Boolean problems. Our experimental results will show the applicability of these algorithms on the basis of several test cases.
Part II - The time after | Pp. 101-111
Getting Köhler to Freiburg
Klaus Eichmann
Integer Linear Programs are widely used in areas such as routing problems, scheduling analysis and optimization, logic synthesis, and partitioning problems. As many of these problems have a Boolean nature, i.e., the variables are restricted to 0 and 1, so called have been proposed. They are mostly based on SAT solvers which took continuous improvements over the past years. However, Pseudo-Boolean solvers are only able to optimize a single linear function while fulfilling several constraints. Unfortunately many real-world optimization problems have multiple objective functions which are often conflicting and have to be optimized simultaneously, resulting in general in a set of optimal solutions. As a consequence, a single-objective Pseudo-Boolean solver will not be able to find this set of optimal solutions. As a remedy, we propose three different algorithms for solving multi-objective Pseudo-Boolean problems. Our experimental results will show the applicability of these algorithms on the basis of several test cases.
Part II - The time after | Pp. 112-120