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Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing

Resumen/Descripción – provisto por la editorial

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Palabras clave – provistas por la editorial

clonal cell population; phenotypic diversity; inoculum train; uncertainty-based; cell culture model; biopharmaceutical manufacturing; Escherichia coli; hybrid modeling; machine learning; model-assisted DoE; quality by design; upstream bioprocessing; surface plasmon resonance (SPR); bioprocess; monitoring; biosensor; quality by design (QbD); process analytical technology (PAT); biotherapeutics production; vaccines production; CHO DP-12; computational fluid dynamics; bioreactor characterization; hydrodynamic gradients; process development; critical shear stress; Kolmogorov length scale; operational space; sensors; cell culture; spectroscopy; PAT; smart biomanufacturing; soft-sensor; Adeno-associated virus; transfection; PEI; continuous; gene therapy; microcarriers; bioreactor; transient expression; spheroid strength; β-cells; diabetes; shear stress-guided production; hydrodynamic stress; Gaussian processes; Bayes optimization; Pareto optimization; multi-objective; seed train; Chinese hamster ovary cells; cryopreservation; monoclonal antibodies; N−1 perfusion; process intensification; upstream processing; n/a

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Información

Tipo de recurso:

libros

ISBN electrónico

978-3-0365-5209-5

País de edición

Suiza