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synergy; 1-(acylamino)alkylphosphonic acids; hydrolytic deacylation; chiral phosphines; organophosphorus chemistry; alcoholysis; electrophilic substitution; NORPHOS; DFT; diphosphines; dry eye syndrome; cyclo-P5; O-derivatization; triple-decker; phosphorylation; molybdenum; NMR-controlled titration; mechanochemistry; N-acyliminium cation; stability constants; Pudovik reaction; phosphonocarboxylic acids; 1; aminophosphonic acids; allylic alkylation; diquafosol; silver; Diels-Alder reaction; QTAIM; dissociation constants; weakly coordinating; substitution; phosphonium salts; amino acids; continuous flow reactor; DFT calculations; metallacycle; 31P NMR spectra of intermediates; dinucleotides; N-acylimine; copper; microwave; 1-aminoalkylphosphonic acids; phosphonic acids; bis(phosphane) palladium complex; denufosol; oxidation; C-H bond activation; asymmetric catalysis; dynamic and specific NMR parameters; electronic parameters; dialkyl H-phosphonates; ?-hydroxyphosphonate; transesterification; polycyclic compounds; stereoselective synthesis; rearrangement; hydrolysis; ?-amidoalkylating agents; 3-azaphospholes