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Artificial Organs
Resumen/Descripción – provisto por la editorial en inglés
Artificial Organs is the official peer reviewed journal of the International Federation for Artificial Organs, the International Faculty for Artificial Organs, and the International Society for Rotary Blood Pumps. Artificial Organs publishes original research articles dealing with research, developments, and clinical applications of artificial organs including organ replacement, recovery, and regeneration. Membership in the organizations listed above is not a prerequisite for publication. Articles are published without charge to the author except in certain circumstances such as color figures. In print since 1977, Artificial Organs continues to publish original articles featuring studies of design, performance, and clinical evaluation of organ systems for the international medical, scientific, and engineering communities involved in the research, development, and clinical application of artificial organ technologies. Artificial Organs invites communications on topics of organ Replacement, Recovery and Regeneration, including articles related to:Palabras clave – provistas por la editorial
surgery; artificial; organs; transplant; review; medicine; heart; kidney; journal; article; hemodial
Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde ene. 1977 / hasta dic. 2023 | Wiley Online Library |
Información
Tipo de recurso:
revistas
ISSN impreso
0160-564X
ISSN electrónico
1525-1594
Editor responsable
John Wiley & Sons, Inc. (WILEY)
País de edición
Reino Unido
Fecha de publicación
1977-
Tabla de contenidos
doi: 10.1111/aor.14074
Comparison on the properties of bovine pericardium and porcine pericardium used as leaflet materials of transcatheter heart valve
Chang Jin
; Li Zhao; Zebin Wu; Bin Li; Ronghui Liu; Hongping He; Lizhen Wang; Weidong Wang
<jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>In order to obtain the smaller delivery diameter, porcine pericardium had been used as a substitute material of bovine pericardium for the leaflet materials of transcatheter heart valve (THV). However, the differences between them had not been fully studied. Therefore, this study compared the microstructure, biochemical and mechanical properties of two materials and hydrodynamics of THV made by the two materials in detail.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>In this study, firstly, the microstructure of pericardium was analyzed by staining and scanning electron microscope; secondly, the biochemical properties of pericardium after different processes were compared by heat shrinkage temperature test, free amino and carboxyl concentration test, enzyme degradation test, subcutaneous implantation calcification analysis in rats; finally, the mechanical properties were evaluated by uniaxial tensile test before and after the pericardium being crimped, and then, the hydrodynamics of THV was studied according to the ISO5840 standard.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Compared with bovine pericardium, after the same process, porcine pericardium showed a looser and tinier fiber bundle, a similar free carboxyl concentration, a lower resistance to enzyme degradation, a significantly lower calcification, bearing capacity and damage after being crimped, a better hydrodynamic and adaption with lower cardiac output and deformation of implantation position. Meanwhile the dehydration process of pericardium almost had preserved all the biochemical advantages of two materials.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>In this study, porcine and bovine pericardium showed some significant differences in biochemical, mechanical properties and hydrodynamics. According to the results, it was presumed that the thinner porcine pericardium might be more suitable for THV of right heart system. Meanwhile, more attention should be taken for the calcification of THV made by the bovine pericardium.</jats:p></jats:sec>
Palabras clave: Biomedical Engineering; General Medicine; Biomaterials; Medicine (miscellaneous); Bioengineering.
Pp. 427-438