Catálogo de publicaciones - revistas

<jats:title>Coding for space in the mammalian brain</jats:title> <jats:p> Nearly all mammals navigate over large spatial scales in environments that span hundreds of meters to many kilometers. However, very little is known about the neural representations that underlie the coding of such large spaces. Eliav <jats:italic>et al.</jats:italic> recorded from place cells in the hippocampus of bats as they flew back and forth on an extremely long track (see the Perspective by Wood and Dudchenko). Many place cells had multiple place fields within this large environment. The place field sizes ranged from less than 1 meter up to 32 meters, and the sizes of the different place fields of an individual cell varied as much as 20-fold. Studying animals under naturalistic conditions can reveal new coding principles for the representation of their environment in the brain. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , abg4020, this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.abg4020">eabg4020</jats:related-article> ; see also abi9663, p. <jats:related-article issue="6545" page="913" related-article-type="in-this-issue" vol="372">913</jats:related-article> </jats:p>

<jats:title>Urban socioeconomics and mortality</jats:title> <jats:p> Santiago, Chile, is a highly segregated city with distinct zones of affluence and deprivation. This setting offers a window on how social factors propel the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic in an economically vulnerable society with high levels of income inequality. Mena <jats:italic>et al.</jats:italic> analyzed incidence and mortality attributed to SARS-CoV-2 to understand spatial variations in disease burden. Infection fatality rates were higher in lower-income municipalities because of comorbidities and lack of access to health care. Disparities between municipalities in the quality of their health care delivery system became apparent in testing delays and capacity. These indicators explain a large part of the variation in COVID-19 underreporting and deaths and show that these inequalities disproportionately affected younger people. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , abg5298, this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.abg5298">eabg5298</jats:related-article> </jats:p>

<jats:p>In the 1920s, E. C. LaRue, a hydrologist at the United States Geological Survey, did an analysis of the Colorado River Basin that revealed the river could not reliably meet future water demands. No one heeded his warning. One hundred years later, water flow through the Colorado River is down by 20% and the basin's Lake Powell and Lake Mead—the nation's two largest reservoirs—are projected to be only 29% full by 2023. This river system, upon which 40 million North Americans in the United States and Mexico depend, is in trouble. But there is an opportunity to manage this crisis. Water allocation agreements from 2007 and 2019, designed to deal with a shrinking river, will be renegotiated over the next 4 years. Will decision-makers and politicians follow the science?</jats:p>

<jats:p>A roundup of weekly science policy and related news.</jats:p>

<jats:p>Soil scientist Asmeret Berhe would take the lead at agency known for funding physics.</jats:p>

<jats:p>Rechargeable batteries based on zinc promise to be cheaper and safer for grid storage.</jats:p>

<jats:p>"Multidomain" trials look for brain benefits from multiple, simultaneous alterations.</jats:p>

<jats:p>Concern grows about the pandemic potential of other members of the virus family.</jats:p>

<jats:p>Updated stem cell guidelines also herald new ways to study development.</jats:p>

<jats:p>Government expected to loosen rules for some biotech crops and animals.</jats:p>