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Nature

Resumen/Descripción – provisto por la editorial en inglés
Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.
Palabras clave – provistas por la editorial

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No detectada desde jul. 2012 / hasta dic. 2023 Nature.com
No detectada desde jul. 2006 / hasta ago. 2012 Ovid

Información

Tipo de recurso:

revistas

ISSN impreso

0028-0836

ISSN electrónico

1476-4687

Editor responsable

Springer Nature

País de edición

Reino Unido

Fecha de publicación

Tabla de contenidos

Microcomb-driven silicon photonic systems

Haowen Shu; Lin ChangORCID; Yuansheng Tao; Bitao Shen; Weiqiang Xie; Ming JinORCID; Andrew Netherton; Zihan Tao; Xuguang Zhang; Ruixuan Chen; Bowen Bai; Jun Qin; Shaohua Yu; Xingjun WangORCID; John E. BowersORCID

<jats:title>Abstract</jats:title><jats:p>Microcombs have sparked a surge of applications over the past decade, ranging from optical communications to metrology<jats:sup>1–4</jats:sup>. Despite their diverse deployment, most microcomb-based systems rely on a large amount of bulky elements and equipment to fulfil their desired functions, which is complicated, expensive and power consuming. By contrast, foundry-based silicon photonics (SiPh) has had remarkable success in providing versatile functionality in a scalable and low-cost manner<jats:sup>5–7</jats:sup>, but its available chip-based light sources lack the capacity for parallelization, which limits the scope of SiPh applications. Here we combine these two technologies by using a power-efficient and operationally simple aluminium-gallium-arsenide-on-insulator microcomb source to drive complementary metal–oxide–semiconductor SiPh engines. We present two important chip-scale photonic systems for optical data transmission and microwave photonics, respectively. A microcomb-based integrated photonic data link is demonstrated, based on a pulse-amplitude four-level modulation scheme with a two-terabit-per-second aggregate rate, and a highly reconfigurable microwave photonic filter with a high level of integration is constructed using a time-stretch approach. Such synergy of a microcomb and SiPh integrated components is an essential step towards the next generation of fully integrated photonic systems.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 457-463

Microfluidic chain reaction of structurally programmed capillary flow events

Mohamed Yafia; Oriol Ymbern; Ayokunle O. Olanrewaju; Azim Parandakh; Ahmad Sohrabi Kashani; Johan Renault; Zijie JinORCID; Geunyong Kim; Andy NgORCID; David JunckerORCID

Palabras clave: Multidisciplinary.

Pp. 464-469

Programmable heating and quenching for efficient thermochemical synthesis

Qi DongORCID; Yonggang Yao; Sichao Cheng; Konstantinos Alexopoulos; Jinlong Gao; Sanjana SrinivasORCID; Yifan Wang; Yong PeiORCID; Chaolun Zheng; Alexandra H. BrozenaORCID; Hao Zhao; Xizheng Wang; Hilal Ezgi Toraman; Bao Yang; Ioannis G. Kevrekidis; Yiguang Ju; Dionisios G. VlachosORCID; Dongxia LiuORCID; Liangbing HuORCID

Palabras clave: Multidisciplinary.

Pp. 470-476

Intermolecular [2π+2σ]-photocycloaddition enabled by triplet energy transfer

Roman Kleinmans; Tobias Pinkert; Subhabrata Dutta; Tiffany O. Paulisch; Hyeyun KeumORCID; Constantin G. Daniliuc; Frank GloriusORCID

Palabras clave: Multidisciplinary.

Pp. 477-482

Synergistic HNO3–H2SO4–NH3 upper tropospheric particle formation

Mingyi WangORCID; Mao Xiao; Barbara BertozziORCID; Guillaume MarieORCID; Birte Rörup; Benjamin Schulze; Roman Bardakov; Xu-Cheng HeORCID; Jiali Shen; Wiebke Scholz; Ruby MartenORCID; Lubna Dada; Rima BaalbakiORCID; Brandon Lopez; Houssni Lamkaddam; Hanna E. Manninen; António Amorim; Farnoush Ataei; Pia Bogert; Zoé BrasseurORCID; Lucía Caudillo; Louis-Philippe De Menezes; Jonathan DuplissyORCID; Annica M. L. EkmanORCID; Henning Finkenzeller; Loïc Gonzalez Carracedo; Manuel Granzin; Roberto Guida; Martin Heinritzi; Victoria Hofbauer; Kristina HöhlerORCID; Kimmo Korhonen; Jordan E. KrechmerORCID; Andreas Kürten; Katrianne LehtipaloORCID; Naser G. A. MahfouzORCID; Vladimir Makhmutov; Dario Massabò; Serge Mathot; Roy L. Mauldin; Bernhard MentlerORCID; Tatjana MüllerORCID; Antti Onnela; Tuukka PetäjäORCID; Maxim PhilippovORCID; Ana A. Piedehierro; Andrea PozzerORCID; Ananth Ranjithkumar; Meredith Schervish; Siegfried Schobesberger; Mario Simon; Yuri Stozhkov; António Tomé; Nsikanabasi Silas Umo; Franziska Vogel; Robert Wagner; Dongyu S. Wang; Stefan K. WeberORCID; André WeltiORCID; Yusheng Wu; Marcel Zauner-WieczorekORCID; Mikko Sipilä; Paul M. Winkler; Armin HanselORCID; Urs Baltensperger; Markku KulmalaORCID; Richard C. FlaganORCID; Joachim CurtiusORCID; Ilona Riipinen; Hamish GordonORCID; Jos LelieveldORCID; Imad El-HaddadORCID; Rainer VolkamerORCID; Douglas R. Worsnop; Theodoros ChristoudiasORCID; Jasper KirkbyORCID; Ottmar Möhler; Neil M. DonahueORCID

<jats:title>Abstract</jats:title><jats:p>New particle formation in the upper free troposphere is a major global source of cloud condensation nuclei (CCN)<jats:sup>1–4</jats:sup>. However, the precursor vapours that drive the process are not well understood. With experiments performed under upper tropospheric conditions in the CERN CLOUD chamber, we show that nitric acid, sulfuric acid and ammonia form particles synergistically, at rates that are orders of magnitude faster than those from any two of the three components. The importance of this mechanism depends on the availability of ammonia, which was previously thought to be efficiently scavenged by cloud droplets during convection. However, surprisingly high concentrations of ammonia and ammonium nitrate have recently been observed in the upper troposphere over the Asian monsoon region<jats:sup>5,6</jats:sup>. Once particles have formed, co-condensation of ammonia and abundant nitric acid alone is sufficient to drive rapid growth to CCN sizes with only trace sulfate. Moreover, our measurements show that these CCN are also highly efficient ice nucleating particles—comparable to desert dust. Our model simulations confirm that ammonia is efficiently convected aloft during the Asian monsoon, driving rapid, multi-acid HNO<jats:sub>3</jats:sub>–H<jats:sub>2</jats:sub>SO<jats:sub>4</jats:sub>–NH<jats:sub>3</jats:sub> nucleation in the upper troposphere and producing ice nucleating particles that spread across the mid-latitude Northern Hemisphere.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 483-489

Expanding ocean food production under climate change

Christopher M. FreeORCID; Reniel B. CabralORCID; Halley E. FroehlichORCID; Willow BattistaORCID; Elena Ojea; Erin O’Reilly; James E. PalardyORCID; Jorge García MolinosORCID; Katherine J. SiegelORCID; Ragnar Arnason; Marie Antonette Juinio-MeñezORCID; Katharina FabriciusORCID; Carol Turley; Steven D. GainesORCID

Palabras clave: Multidisciplinary.

Pp. 490-496

A natural mutator allele shapes mutation spectrum variation in mice

Thomas A. Sasani; David G. AshbrookORCID; Annabel C. BeichmanORCID; Lu Lu; Abraham A. PalmerORCID; Robert W. Williams; Jonathan K. PritchardORCID; Kelley HarrisORCID

Palabras clave: Multidisciplinary.

Pp. 497-502

Genetic and chemotherapeutic influences on germline hypermutation

Joanna Kaplanis; Benjamin Ide; Rashesh SanghviORCID; Matthew NevilleORCID; Petr Danecek; Tim CoorensORCID; Elena PrigmoreORCID; Patrick Short; Giuseppe Gallone; Jeremy McRaeORCID; Loukas Moutsianas; Chris Odhams; Jenny Carmichael; Angela Barnicoat; Helen Firth; Patrick O’BrienORCID; Raheleh RahbariORCID; Matthew HurlesORCID;

<jats:title>Abstract</jats:title><jats:p>Mutations in the germline generates all evolutionary genetic variation and is a cause of genetic disease. Parental age is the primary determinant of the number of new germline mutations in an individual’s genome<jats:sup>1,2</jats:sup>. Here we analysed the genome-wide sequences of 21,879 families with rare genetic diseases and identified 12 individuals with a hypermutated genome with between two and seven times more de novo single-nucleotide variants than expected. In most families (9 out of 12), the excess mutations came from the father. Two families had genetic drivers of germline hypermutation, with fathers carrying damaging genetic variation in DNA-repair genes. For five of the families, paternal exposure to chemotherapeutic agents before conception was probably a key driver of hypermutation. Our results suggest that the germline is well protected from mutagenic effects, hypermutation is rare, the number of excess mutations is relatively modest and most individuals with a hypermutated genome will not have a genetic disease.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 503-508

Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17

Tal Iram; Fabian KernORCID; Achint Kaur; Saket MyneniORCID; Allison R. MorningstarORCID; Heather Shin; Miguel A. Garcia; Lakshmi Yerra; Robert Palovics; Andrew C. YangORCID; Oliver Hahn; Nannan Lu; Steven R. Shuken; Michael S. Haney; Benoit Lehallier; Manasi Iyer; Jian LuoORCID; Henrik ZetterbergORCID; Andreas Keller; J. Bradley Zuchero; Tony Wyss-CorayORCID

Palabras clave: Multidisciplinary.

Pp. 509-515

Left–right symmetry of zebrafish embryos requires somite surface tension

Sundar R. NaganathanORCID; Marko PopovićORCID; Andrew C. OatesORCID

Palabras clave: Multidisciplinary.

Pp. 516-521