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Nature
Resumen/Descripción – provisto por la editorial en inglés
Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.Palabras clave – provistas por la editorial
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Disponibilidad
Institución detectada | Período | Navegá | Descargá | Solicitá |
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No detectada | desde jul. 2012 / hasta dic. 2023 | Nature.com | ||
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Información
Tipo de recurso:
revistas
ISSN impreso
0028-0836
ISSN electrónico
1476-4687
Editor responsable
Springer Nature
País de edición
Reino Unido
Fecha de publicación
1869-
Tabla de contenidos
Microcomb-driven silicon photonic systems
Haowen Shu; Lin Chang; Yuansheng Tao; Bitao Shen; Weiqiang Xie; Ming Jin; Andrew Netherton; Zihan Tao; Xuguang Zhang; Ruixuan Chen; Bowen Bai; Jun Qin; Shaohua Yu; Xingjun Wang; John E. Bowers
<jats:title>Abstract</jats:title><jats:p>Microcombs have sparked a surge of applications over the past decade, ranging from optical communications to metrology<jats:sup>1–4</jats:sup>. Despite their diverse deployment, most microcomb-based systems rely on a large amount of bulky elements and equipment to fulfil their desired functions, which is complicated, expensive and power consuming. By contrast, foundry-based silicon photonics (SiPh) has had remarkable success in providing versatile functionality in a scalable and low-cost manner<jats:sup>5–7</jats:sup>, but its available chip-based light sources lack the capacity for parallelization, which limits the scope of SiPh applications. Here we combine these two technologies by using a power-efficient and operationally simple aluminium-gallium-arsenide-on-insulator microcomb source to drive complementary metal–oxide–semiconductor SiPh engines. We present two important chip-scale photonic systems for optical data transmission and microwave photonics, respectively. A microcomb-based integrated photonic data link is demonstrated, based on a pulse-amplitude four-level modulation scheme with a two-terabit-per-second aggregate rate, and a highly reconfigurable microwave photonic filter with a high level of integration is constructed using a time-stretch approach. Such synergy of a microcomb and SiPh integrated components is an essential step towards the next generation of fully integrated photonic systems.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 457-463
Microfluidic chain reaction of structurally programmed capillary flow events
Mohamed Yafia; Oriol Ymbern; Ayokunle O. Olanrewaju; Azim Parandakh; Ahmad Sohrabi Kashani; Johan Renault; Zijie Jin; Geunyong Kim; Andy Ng; David Juncker
Palabras clave: Multidisciplinary.
Pp. 464-469
Programmable heating and quenching for efficient thermochemical synthesis
Qi Dong; Yonggang Yao; Sichao Cheng; Konstantinos Alexopoulos; Jinlong Gao; Sanjana Srinivas; Yifan Wang; Yong Pei; Chaolun Zheng; Alexandra H. Brozena; Hao Zhao; Xizheng Wang; Hilal Ezgi Toraman; Bao Yang; Ioannis G. Kevrekidis; Yiguang Ju; Dionisios G. Vlachos; Dongxia Liu; Liangbing Hu
Palabras clave: Multidisciplinary.
Pp. 470-476
Intermolecular [2π+2σ]-photocycloaddition enabled by triplet energy transfer
Roman Kleinmans; Tobias Pinkert; Subhabrata Dutta; Tiffany O. Paulisch; Hyeyun Keum; Constantin G. Daniliuc; Frank Glorius
Palabras clave: Multidisciplinary.
Pp. 477-482
Synergistic HNO3–H2SO4–NH3 upper tropospheric particle formation
Mingyi Wang; Mao Xiao; Barbara Bertozzi; Guillaume Marie; Birte Rörup; Benjamin Schulze; Roman Bardakov; Xu-Cheng He; Jiali Shen; Wiebke Scholz; Ruby Marten; Lubna Dada; Rima Baalbaki; Brandon Lopez; Houssni Lamkaddam; Hanna E. Manninen; António Amorim; Farnoush Ataei; Pia Bogert; Zoé Brasseur; Lucía Caudillo; Louis-Philippe De Menezes; Jonathan Duplissy; Annica M. L. Ekman; Henning Finkenzeller; Loïc Gonzalez Carracedo; Manuel Granzin; Roberto Guida; Martin Heinritzi; Victoria Hofbauer; Kristina Höhler; Kimmo Korhonen; Jordan E. Krechmer; Andreas Kürten; Katrianne Lehtipalo; Naser G. A. Mahfouz; Vladimir Makhmutov; Dario Massabò; Serge Mathot; Roy L. Mauldin; Bernhard Mentler; Tatjana Müller; Antti Onnela; Tuukka Petäjä; Maxim Philippov; Ana A. Piedehierro; Andrea Pozzer; Ananth Ranjithkumar; Meredith Schervish; Siegfried Schobesberger; Mario Simon; Yuri Stozhkov; António Tomé; Nsikanabasi Silas Umo; Franziska Vogel; Robert Wagner; Dongyu S. Wang; Stefan K. Weber; André Welti; Yusheng Wu; Marcel Zauner-Wieczorek; Mikko Sipilä; Paul M. Winkler; Armin Hansel; Urs Baltensperger; Markku Kulmala; Richard C. Flagan; Joachim Curtius; Ilona Riipinen; Hamish Gordon; Jos Lelieveld; Imad El-Haddad; Rainer Volkamer; Douglas R. Worsnop; Theodoros Christoudias; Jasper Kirkby; Ottmar Möhler; Neil M. Donahue
<jats:title>Abstract</jats:title><jats:p>New particle formation in the upper free troposphere is a major global source of cloud condensation nuclei (CCN)<jats:sup>1–4</jats:sup>. However, the precursor vapours that drive the process are not well understood. With experiments performed under upper tropospheric conditions in the CERN CLOUD chamber, we show that nitric acid, sulfuric acid and ammonia form particles synergistically, at rates that are orders of magnitude faster than those from any two of the three components. The importance of this mechanism depends on the availability of ammonia, which was previously thought to be efficiently scavenged by cloud droplets during convection. However, surprisingly high concentrations of ammonia and ammonium nitrate have recently been observed in the upper troposphere over the Asian monsoon region<jats:sup>5,6</jats:sup>. Once particles have formed, co-condensation of ammonia and abundant nitric acid alone is sufficient to drive rapid growth to CCN sizes with only trace sulfate. Moreover, our measurements show that these CCN are also highly efficient ice nucleating particles—comparable to desert dust. Our model simulations confirm that ammonia is efficiently convected aloft during the Asian monsoon, driving rapid, multi-acid HNO<jats:sub>3</jats:sub>–H<jats:sub>2</jats:sub>SO<jats:sub>4</jats:sub>–NH<jats:sub>3</jats:sub> nucleation in the upper troposphere and producing ice nucleating particles that spread across the mid-latitude Northern Hemisphere.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 483-489
Expanding ocean food production under climate change
Christopher M. Free; Reniel B. Cabral; Halley E. Froehlich; Willow Battista; Elena Ojea; Erin O’Reilly; James E. Palardy; Jorge García Molinos; Katherine J. Siegel; Ragnar Arnason; Marie Antonette Juinio-Meñez; Katharina Fabricius; Carol Turley; Steven D. Gaines
Palabras clave: Multidisciplinary.
Pp. 490-496
A natural mutator allele shapes mutation spectrum variation in mice
Thomas A. Sasani; David G. Ashbrook; Annabel C. Beichman; Lu Lu; Abraham A. Palmer; Robert W. Williams; Jonathan K. Pritchard; Kelley Harris
Palabras clave: Multidisciplinary.
Pp. 497-502
Genetic and chemotherapeutic influences on germline hypermutation
Joanna Kaplanis; Benjamin Ide; Rashesh Sanghvi; Matthew Neville; Petr Danecek; Tim Coorens; Elena Prigmore; Patrick Short; Giuseppe Gallone; Jeremy McRae; Loukas Moutsianas; Chris Odhams; Jenny Carmichael; Angela Barnicoat; Helen Firth; Patrick O’Brien; Raheleh Rahbari; Matthew Hurles;
<jats:title>Abstract</jats:title><jats:p>Mutations in the germline generates all evolutionary genetic variation and is a cause of genetic disease. Parental age is the primary determinant of the number of new germline mutations in an individual’s genome<jats:sup>1,2</jats:sup>. Here we analysed the genome-wide sequences of 21,879 families with rare genetic diseases and identified 12 individuals with a hypermutated genome with between two and seven times more de novo single-nucleotide variants than expected. In most families (9 out of 12), the excess mutations came from the father. Two families had genetic drivers of germline hypermutation, with fathers carrying damaging genetic variation in DNA-repair genes. For five of the families, paternal exposure to chemotherapeutic agents before conception was probably a key driver of hypermutation. Our results suggest that the germline is well protected from mutagenic effects, hypermutation is rare, the number of excess mutations is relatively modest and most individuals with a hypermutated genome will not have a genetic disease.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 503-508
Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17
Tal Iram; Fabian Kern; Achint Kaur; Saket Myneni; Allison R. Morningstar; Heather Shin; Miguel A. Garcia; Lakshmi Yerra; Robert Palovics; Andrew C. Yang; Oliver Hahn; Nannan Lu; Steven R. Shuken; Michael S. Haney; Benoit Lehallier; Manasi Iyer; Jian Luo; Henrik Zetterberg; Andreas Keller; J. Bradley Zuchero; Tony Wyss-Coray
Palabras clave: Multidisciplinary.
Pp. 509-515