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Nature

Resumen/Descripción – provisto por la editorial en inglés
Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.
Palabras clave – provistas por la editorial

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No detectada desde jul. 2012 / hasta dic. 2023 Nature.com
No detectada desde jul. 2006 / hasta ago. 2012 Ovid

Información

Tipo de recurso:

revistas

ISSN impreso

0028-0836

ISSN electrónico

1476-4687

Editor responsable

Springer Nature

País de edición

Reino Unido

Fecha de publicación

Tabla de contenidos

A repeating fast radio burst source in a globular cluster

F. KirstenORCID; B. MarcoteORCID; K. NimmoORCID; J. W. T. HesselsORCID; M. Bhardwaj; S. P. Tendulkar; A. KeimpemaORCID; J. YangORCID; M. P. SneldersORCID; P. ScholzORCID; A. B. PearlmanORCID; C. J. Law; W. M. PetersORCID; M. GirolettiORCID; Z. ParagiORCID; C. BassaORCID; D. M. HewittORCID; U. Bach; V. BezrukovsORCID; M. BurgayORCID; S. T. ButtaccioORCID; J. E. Conway; A. Corongiu; R. Feiler; O. Forssén; M. P. Gawroński; R. KaruppusamyORCID; M. A. Kharinov; M. Lindqvist; G. MaccaferriORCID; A. MelnikovORCID; O. S. Ould-BoukattineORCID; A. PossentiORCID; G. SurcisORCID; N. WangORCID; J. Yuan; K. AggarwalORCID; R. Anna-Thomas; G. C. BowerORCID; R. Blaauw; S. Burke-Spolaor; T. CassanelliORCID; T. E. Clarke; E. FonsecaORCID; B. M. GaenslerORCID; A. Gopinath; V. M. KaspiORCID; N. KassimORCID; T. J. W. Lazio; C. LeungORCID; D. Z. LiORCID; H. H. LinORCID; K. W. MasuiORCID; R. Mckinven; D. MichilliORCID; A. G. MikhailovORCID; C. Ng; A. Orbidans; U. L. PenORCID; E. PetroffORCID; M. Rahman; S. M. RansomORCID; K. ShinORCID; K. M. Smith; I. H. Stairs; W. VlemmingsORCID

Palabras clave: Multidisciplinary.

Pp. 585-589

Quantum sensing for gravity cartography

Ben StrayORCID; Andrew LambORCID; Aisha KaushikORCID; Jamie VovroshORCID; Anthony RodgersORCID; Jonathan Winch; Farzad HayatiORCID; Daniel BoddiceORCID; Artur Stabrawa; Alexander Niggebaum; Mehdi LangloisORCID; Yu-Hung LienORCID; Samuel Lellouch; Sanaz RoshanmaneshORCID; Kevin RidleyORCID; Geoffrey de Villiers; Gareth Brown; Trevor Cross; George Tuckwell; Asaad Faramarzi; Nicole MetjeORCID; Kai BongsORCID; Michael HolynskiORCID

<jats:title>Abstract</jats:title><jats:p>The sensing of gravity has emerged as a tool in geophysics applications such as engineering and climate research<jats:sup>1–3</jats:sup>, including the monitoring of temporal variations in aquifers<jats:sup>4</jats:sup> and geodesy<jats:sup>5</jats:sup>. However, it is impractical to use gravity cartography to resolve metre-scale underground features because of the long measurement times needed for the removal of vibrational noise<jats:sup>6</jats:sup>. Here we overcome this limitation by realizing a practical quantum gravity gradient sensor. Our design suppresses the effects of micro-seismic and laser noise, thermal and magnetic field variations, and instrument tilt. The instrument achieves a statistical uncertainty of 20 E (1 E = 10<jats:sup>−9</jats:sup> s<jats:sup>−2</jats:sup>) and is used to perform a 0.5-metre-spatial-resolution survey across an 8.5-metre-long line, detecting a 2-metre tunnel with a signal-to-noise ratio of 8. Using a Bayesian inference method, we determine the centre to ±0.19 metres horizontally and the centre depth as (1.89 −0.59/+2.3) metres. The removal of vibrational noise enables improvements in instrument performance to directly translate into reduced measurement time in mapping. The sensor parameters are compatible with applications in mapping aquifers and evaluating impacts on the water table<jats:sup>7</jats:sup>, archaeology<jats:sup>8–11</jats:sup>, determination of soil properties<jats:sup>12</jats:sup> and water content<jats:sup>13</jats:sup>, and reducing the risk of unforeseen ground conditions in the construction of critical energy, transport and utilities infrastructure<jats:sup>14</jats:sup>, providing a new window into the underground.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 590-594

Hyperbolic shear polaritons in low-symmetry crystals

Nikolai C. Passler; Xiang Ni; Guangwei HuORCID; Joseph R. Matson; Giulia Carini; Martin Wolf; Mathias Schubert; Andrea AlùORCID; Joshua D. CaldwellORCID; Thomas G. FollandORCID; Alexander PaarmannORCID

<jats:title>Abstract</jats:title><jats:p>The lattice symmetry of a crystal is one of the most important factors in determining its physical properties. Particularly, low-symmetry crystals offer powerful opportunities to control light propagation, polarization and phase<jats:sup>1–4</jats:sup>. Materials featuring extreme optical anisotropy can support a hyperbolic response, enabling coupled light–matter interactions, also known as polaritons, with highly directional propagation and compression of light to deeply sub-wavelength scales<jats:sup>5</jats:sup>. Here we show that monoclinic crystals can support hyperbolic shear polaritons, a new polariton class arising in the mid-infrared to far-infrared due to shear phenomena in the dielectric response. This feature emerges in materials in which the dielectric tensor cannot be diagonalized, that is, in low-symmetry monoclinic and triclinic crystals in which several oscillators with non-orthogonal relative orientations contribute to the optical response<jats:sup>6,7</jats:sup>. Hyperbolic shear polaritons complement previous observations of hyperbolic phonon polaritons in orthorhombic<jats:sup>1,3,4</jats:sup> and hexagonal<jats:sup>8,9</jats:sup> crystal systems, unveiling new features, such as the continuous evolution of their propagation direction with frequency, tilted wavefronts and asymmetric responses. The interplay between diagonal loss and off-diagonal shear phenomena in the dielectric response of these materials has implications for new forms of non-Hermitian and topological photonic states. We anticipate that our results will motivate new directions for polariton physics in low-symmetry materials, which include geological minerals<jats:sup>10</jats:sup>, many common oxides<jats:sup>11</jats:sup> and organic crystals<jats:sup>12</jats:sup>, greatly expanding the material base and extending design opportunities for compact photonic devices.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 595-600

Evidence for a single-layer van der Waals multiferroic

Qian Song; Connor A. OcchialiniORCID; Emre Ergeçen; Batyr IlyasORCID; Danila Amoroso; Paolo BaroneORCID; Jesse Kapeghian; Kenji WatanabeORCID; Takashi TaniguchiORCID; Antia S. BotanaORCID; Silvia Picozzi; Nuh GedikORCID; Riccardo CominORCID

Palabras clave: Multidisciplinary.

Pp. 601-605

Free-standing homochiral 2D monolayers by exfoliation of molecular crystals

Jinqiao Dong; Lingmei Liu; Chunxia Tan; Qisong XuORCID; Jiachen Zhang; Zhiwei Qiao; Dandan ChuORCID; Yan LiuORCID; Qun ZhangORCID; Jianwen JiangORCID; Yu HanORCID; Anthony P. DavisORCID; Yong CuiORCID

Palabras clave: Multidisciplinary.

Pp. 606-611

Emergent constraints on future precipitation changes

Hideo ShiogamaORCID; Masahiro WatanabeORCID; Hyungjun KimORCID; Nagio Hirota

Palabras clave: Multidisciplinary.

Pp. 612-616

Observed poleward freshwater transport since 1970

Taimoor SohailORCID; Jan D. ZikaORCID; Damien B. IrvingORCID; John A. ChurchORCID

Palabras clave: Multidisciplinary.

Pp. 617-622

Signatures of TOP1 transcription-associated mutagenesis in cancer and germline

Martin A. M. ReijnsORCID; David A. ParryORCID; Thomas C. WilliamsORCID; Ferran NadeuORCID; Rebecca L. Hindshaw; Diana O. Rios SzwedORCID; Michael D. NicholsonORCID; Paula Carroll; Shelagh Boyle; Romina Royo; Alex J. CornishORCID; Hang Xiang; Kate Ridout; John C. Ambrose; Prabhu Arumugam; Roel Bevers; Marta Bleda; Freya Boardman-Pretty; Christopher R. Boustred; Helen Brittain; Mark J. Caulfield; Georgia C. Chan; Greg Elgar; Tom Fowler; Adam Giess; Angela Hamblin; Shirley Henderson; Tim J. P. Hubbard; Rob Jackson; Louise J. Jones; Dalia Kasperaviciute; Melis Kayikci; Athanasios Kousathanas; Lea Lahnstein; Sarah E. A. Leigh; Ivonne U. S. Leong; Javier F. Lopez; Fiona Maleady-Crowe; Meriel McEntagart; Federico Minneci; Loukas Moutsianas; Michael Mueller; Nirupa Murugaesu; Anna C. Need; Peter O’Donovan; Chris A. Odhams; Christine Patch; Mariana Buongermino Pereira; Daniel Perez-Gil; John Pullinger; Tahrima Rahim; Augusto Rendon; Tim Rogers; Kevin Savage; Kushmita Sawant; Richard H. Scott; Afshan Siddiq; Alexander Sieghart; Samuel C. Smith; Alona Sosinsky; Alexander Stuckey; Mélanie Tanguy; Ana Lisa Taylor Tavares; Ellen R. A. Thomas; Simon R. Thompson; Arianna Tucci; Matthew J. Welland; Eleanor Williams; Katarzyna Witkowska; Suzanne M. Wood; Daniel Chubb; Alex Cornish; Ben Kinnersley; Richard Houlston; David Wedge; Andreas Gruber; Anna Frangou; William Cross; Trevor Graham; Andrea Sottoriva; Gulio Caravagna; Nuria Lopez-Bigas; Claudia Arnedo-Pac; David Church; Richard Culliford; Steve Thorn; Phil Quirke; Henry Wood; Ian Tomlinson; Boris Noyvert; Anna SchuhORCID; Konrad Aden; Claire PallesORCID; Elias CampoORCID; Tatjana StankovicORCID; Martin S. TaylorORCID; Andrew P. JacksonORCID; ;

<jats:title>Abstract</jats:title><jats:p>The mutational landscape is shaped by many processes. Genic regions are vulnerable to mutation but are preferentially protected by transcription-coupled repair<jats:sup>1</jats:sup>. In microorganisms, transcription has been demonstrated to be mutagenic<jats:sup>2,3</jats:sup>; however, the impact of transcription-associated mutagenesis remains to be established in higher eukaryotes<jats:sup>4</jats:sup>. Here we show that ID4—a cancer insertion–deletion (indel) mutation signature of unknown aetiology<jats:sup>5</jats:sup> characterized by short (2 to 5 base pair) deletions —is due to a transcription-associated mutagenesis process. We demonstrate that defective ribonucleotide excision repair in mammals is associated with the ID4 signature, with mutations occurring at a TNT sequence motif, implicating topoisomerase 1 (TOP1) activity at sites of genome-embedded ribonucleotides as a mechanistic basis. Such TOP1-mediated deletions occur somatically in cancer, and the ID-TOP1 signature is also found in physiological settings, contributing to genic de novo indel mutations in the germline. Thus, although topoisomerases protect against genome instability by relieving topological stress<jats:sup>6</jats:sup>, their activity may also be an important source of mutations in the human genome.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 623-631

A nutrient-specific gut hormone arbitrates between courtship and feeding

Hui-Hao Lin; Meihua Christina Kuang; Imran Hossain; Yinan Xuan; Laura Beebe; Andrew K. Shepherd; Marco Rolandi; Jing W. WangORCID

Palabras clave: Multidisciplinary.

Pp. 632-638

A discrete neuronal population coordinates brain-wide developmental activity

Bryce T. Bajar; Nguyen T. PhiORCID; Jesse Isaacman-Beck; Jun Reichl; Harpreet Randhawa; Orkun AkinORCID

Palabras clave: Multidisciplinary.

Pp. 639-646