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Nature
Resumen/Descripción – provisto por la editorial en inglés
Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.Palabras clave – provistas por la editorial
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Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde jul. 2012 / hasta dic. 2023 | Nature.com | ||
| No detectada | desde jul. 2006 / hasta ago. 2012 | Ovid |
Información
Tipo de recurso:
revistas
ISSN impreso
0028-0836
ISSN electrónico
1476-4687
Editor responsable
Springer Nature
País de edición
Reino Unido
Fecha de publicación
1869-
Tabla de contenidos
Light detection nears its quantum limit
Sebastian Klembt
Palabras clave: Multidisciplinary.
Pp. 483-484
Quenching of star formation from a lack of inflowing gas to galaxies
Katherine E. Whitaker
; Christina C. Williams; Lamiya Mowla; Justin S. Spilker; Sune Toft; Desika Narayanan; Alexandra Pope; Georgios E. Magdis; Pieter G. van Dokkum; Mohammad Akhshik; Rachel Bezanson; Gabriel B. Brammer; Joel Leja; Allison Man; Erica J. Nelson; Johan Richard; Camilla Pacifici; Keren Sharon; Francesco Valentino
Palabras clave: Multidisciplinary.
Pp. 485-488
Normal, dust-obscured galaxies in the epoch of reionization
Y. Fudamoto; P. A. Oesch; S. Schouws; M. Stefanon; R. Smit; R. J. Bouwens; R. A. A. Bowler; R. Endsley; V. Gonzalez; H. Inami; I. Labbe; D. Stark; M. Aravena; L. Barrufet; E. da Cunha; P. Dayal; A. Ferrara; L. Graziani; J. Hodge; A. Hutter; Y. Li; I. De Looze; T. Nanayakkara; A. Pallottini; D. Riechers; R. Schneider; G. Ucci; P. van der Werf; C. White
Palabras clave: Multidisciplinary.
Pp. 489-492
Single-photon nonlinearity at room temperature
Anton V. Zasedatelev; Anton V. Baranikov; Denis Sannikov; Darius Urbonas; Fabio Scafirimuto; Vladislav Yu. Shishkov; Evgeny S. Andrianov; Yurii E. Lozovik; Ullrich Scherf; Thilo Stöferle; Rainer F. Mahrt; Pavlos G. Lagoudakis
Palabras clave: Multidisciplinary.
Pp. 493-497
Electron phase-space control in photonic chip-based particle acceleration
R. Shiloh; J. Illmer; T. Chlouba; P. Yousefi; N. Schönenberger; U. Niedermayer; A. Mittelbach; P. Hommelhoff
Palabras clave: Multidisciplinary.
Pp. 498-502
Three-dimensional electronic microfliers inspired by wind-dispersed seeds
Bong Hoon Kim; Kan Li; Jin-Tae Kim; Yoonseok Park; Hokyung Jang; Xueju Wang; Zhaoqian Xie; Sang Min Won; Hong-Joon Yoon; Geumbee Lee; Woo Jin Jang; Kun Hyuck Lee; Ted S. Chung; Yei Hwan Jung; Seung Yun Heo; Yechan Lee; Juyun Kim; Tengfei Cai; Yeonha Kim; Poom Prasopsukh; Yongjoon Yu; Xinge Yu; Raudel Avila; Haiwen Luan; Honglie Song; Feng Zhu; Ying Zhao; Lin Chen; Seung Ho Han; Jiwoong Kim; Soong Ju Oh; Heon Lee; Chi Hwan Lee; Yonggang Huang; Leonardo P. Chamorro; Yihui Zhang; John A. Rogers
Palabras clave: Multidisciplinary.
Pp. 503-510
Three-dimensional magnetic stripes require slow cooling in fast-spread lower ocean crust
Sarah M. Maher; Jeffrey S. Gee; Michael J. Cheadle; Barbara E. John
Palabras clave: Multidisciplinary.
Pp. 511-515
How deregulation, drought and increasing fire impact Amazonian biodiversity
Xiao Feng; Cory Merow; Zhihua Liu; Daniel S. Park; Patrick R. Roehrdanz; Brian Maitner; Erica A. Newman; Brad L. Boyle; Aaron Lien; Joseph R. Burger; Mathias M. Pires; Paulo M. Brando; Mark B. Bush; Crystal N. H. McMichael; Danilo M. Neves; Efthymios I. Nikolopoulos; Scott R. Saleska; Lee Hannah; David D. Breshears; Tom P. Evans; José R. Soto; Kacey C. Ernst; Brian J. Enquist
Palabras clave: Multidisciplinary.
Pp. 516-521
Paths and timings of the peopling of Polynesia inferred from genomic networks
Alexander G. Ioannidis; Javier Blanco-Portillo; Karla Sandoval; Erika Hagelberg; Carmina Barberena-Jonas; Adrian V. S. Hill; Juan Esteban Rodríguez-Rodríguez; Keolu Fox; Kathryn Robson; Sonia Haoa-Cardinali; Consuelo D. Quinto-Cortés; Juan Francisco Miquel-Poblete; Kathryn Auckland; Tom Parks; Abdul Salam M. Sofro; María C. Ávila-Arcos; Alexandra Sockell; Julian R. Homburger; Celeste Eng; Scott Huntsman; Esteban G. Burchard; Christopher R. Gignoux; Ricardo A. Verdugo; Mauricio Moraga; Carlos D. Bustamante; Alexander J. Mentzer; Andrés Moreno-Estrada
Palabras clave: Multidisciplinary.
Pp. 522-526
Rare variant contribution to human disease in 281,104 UK Biobank exomes
Quanli Wang; Ryan S. Dhindsa; Keren Carss; Andrew R. Harper; Abhishek Nag; Ioanna Tachmazidou; Dimitrios Vitsios; Sri V. V. Deevi; Alex Mackay; Daniel Muthas; Michael Hühn; Susan Monkley; Henric Olsson; Bastian R. Angermann; Ronen Artzi; Carl Barrett; Maria Belvisi; Mohammad Bohlooly-Y; Oliver Burren; Lisa Buvall; Benjamin Challis; Sophia Cameron-Christie; Suzanne Cohen; Andrew Davis; Regina F. Danielson; Brian Dougherty; Benjamin Georgi; Zara Ghazoui; Pernille B. L. Hansen; Fengyuan Hu; Magda Jeznach; Xiao Jiang; Chanchal Kumar; Zhongwu Lai; Glenda Lassi; Samuel H. Lewis; Bolan Linghu; Kieren Lythgow; Peter Maccallum; Carla Martins; Athena Matakidou; Erik Michaëlsson; Sven Moosmang; Sean O’Dell; Yoichiro Ohne; Joel Okae; Amanda O’Neill; Dirk S. Paul; Anna Reznichenko; Michael A Snowden; Anna Walentinsson; Jorge Zeron; Menelas N. Pangalos; Sebastian Wasilewski; Katherine R. Smith; Ruth March; Adam Platt; Carolina Haefliger; Slavé Petrovski;
<jats:title>Abstract</jats:title><jats:p>Genome-wide association studies have uncovered thousands of common variants associated with human disease, but the contribution of rare variants to common disease remains relatively unexplored. The UK Biobank contains detailed phenotypic data linked to medical records for approximately 500,000 participants, offering an unprecedented opportunity to evaluate the effect of rare variation on a broad collection of traits<jats:sup>1,2</jats:sup>. Here we study the relationships between rare protein-coding variants and 17,361 binary and 1,419 quantitative phenotypes using exome sequencing data from 269,171 UK Biobank participants of European ancestry. Gene-based collapsing analyses revealed 1,703 statistically significant gene–phenotype associations for binary traits, with a median odds ratio of 12.4. Furthermore, 83% of these associations were undetectable via single-variant association tests, emphasizing the power of gene-based collapsing analysis in the setting of high allelic heterogeneity. Gene–phenotype associations were also significantly enriched for loss-of-function-mediated traits and approved drug targets. Finally, we performed ancestry-specific and pan-ancestry collapsing analyses using exome sequencing data from 11,933 UK Biobank participants of African, East Asian or South Asian ancestry. Our results highlight a significant contribution of rare variants to common disease. Summary statistics are publicly available through an interactive portal (<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://azphewas.com/">http://azphewas.com/</jats:ext-link>).</jats:p>
Palabras clave: Multidisciplinary.
Pp. 527-532