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Nature
Resumen/Descripción – provisto por la editorial en inglés
Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.Palabras clave – provistas por la editorial
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Disponibilidad
Institución detectada | Período | Navegá | Descargá | Solicitá |
---|---|---|---|---|
No detectada | desde jul. 2012 / hasta dic. 2023 | Nature.com | ||
No detectada | desde jul. 2006 / hasta ago. 2012 | Ovid |
Información
Tipo de recurso:
revistas
ISSN impreso
0028-0836
ISSN electrónico
1476-4687
Editor responsable
Springer Nature
País de edición
Reino Unido
Fecha de publicación
1869-
Tabla de contenidos
Deciphering the immunopeptidome in vivo reveals new tumour antigens
Alex M. Jaeger; Lauren E. Stopfer; Ryuhjin Ahn; Emma A. Sanders; Demi A. Sandel; William A. Freed-Pastor; William M. Rideout; Santiago Naranjo; Tim Fessenden; Kim B. Nguyen; Peter S. Winter; Ryan E. Kohn; Peter M. K. Westcott; Jason M. Schenkel; Sean-Luc Shanahan; Alex K. Shalek; Stefani Spranger; Forest M. White; Tyler Jacks
Palabras clave: Multidisciplinary.
Pp. 149-155
The metastatic spread of breast cancer accelerates during sleep
Zoi Diamantopoulou; Francesc Castro-Giner; Fabienne Dominique Schwab; Christiane Foerster; Massimo Saini; Selina Budinjas; Karin Strittmatter; Ilona Krol; Bettina Seifert; Viola Heinzelmann-Schwarz; Christian Kurzeder; Christoph Rochlitz; Marcus Vetter; Walter Paul Weber; Nicola Aceto
Palabras clave: Multidisciplinary.
Pp. 156-162
GREM1 is required to maintain cellular heterogeneity in pancreatic cancer
Linxiang Lan; Theodore Evan; Huafu Li; Aasia Hussain; E. Josue Ruiz; May Zaw Thin; Rute M. M. Ferreira; Hari Ps; Eva M. Riising; Yoh Zen; Jorge Almagro; Kevin W. Ng; Pablo Soro-Barrio; Jessica Nelson; Gabriela Koifman; Joana Carvalho; Emma L. Nye; Yulong He; Changhua Zhang; Anguraj Sadanandam; Axel Behrens
Palabras clave: Multidisciplinary.
Pp. 163-168
OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage
Xiaoli S. Wu; Xue-Yan He; Jonathan J. Ipsaro; Yu-Han Huang; Jonathan B. Preall; David Ng; Yan Ting Shue; Julien Sage; Mikala Egeblad; Leemor Joshua-Tor; Christopher R. Vakoc
Palabras clave: Multidisciplinary.
Pp. 169-175
Compatibility rules of human enhancer and promoter sequences
Drew T. Bergman; Thouis R. Jones; Vincent Liu; Judhajeet Ray; Evelyn Jagoda; Layla Siraj; Helen Y. Kang; Joseph Nasser; Michael Kane; Antonio Rios; Tung H. Nguyen; Sharon R. Grossman; Charles P. Fulco; Eric S. Lander; Jesse M. Engreitz
Palabras clave: Multidisciplinary.
Pp. 176-184
eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining
Christopher P. Lapointe; Rosslyn Grosely; Masaaki Sokabe; Carlos Alvarado; Jinfan Wang; Elizabeth Montabana; Nancy Villa; Byung-Sik Shin; Thomas E. Dever; Christopher S. Fraser; Israel S. Fernández; Joseph D. Puglisi
Palabras clave: Multidisciplinary.
Pp. 185-190
Cryo-EM structure of a type IV secretion system
Kévin Macé; Abhinav K. Vadakkepat; Adam Redzej; Natalya Lukoyanova; Clasien Oomen; Nathalie Braun; Marta Ukleja; Fang Lu; Tiago R. D. Costa; Elena V. Orlova; David Baker; Qian Cong; Gabriel Waksman
<jats:title>Abstract</jats:title><jats:p>Bacterial conjugation is the fundamental process of unidirectional transfer of DNAs, often plasmid DNAs, from a donor cell to a recipient cell<jats:sup>1</jats:sup>. It is the primary means by which antibiotic resistance genes spread among bacterial populations<jats:sup>2,3</jats:sup>. In Gram-negative bacteria, conjugation is mediated by a large transport apparatus—the conjugative type IV secretion system (T4SS)—produced by the donor cell and embedded in both its outer and inner membranes. The T4SS also elaborates a long extracellular filament—the conjugative pilus—that is essential for DNA transfer<jats:sup>4,5</jats:sup>. Here we present a high-resolution cryo-electron microscopy (cryo-EM) structure of a 2.8 megadalton T4SS complex composed of 92 polypeptides representing 8 of the 10 essential T4SS components involved in pilus biogenesis. We added the two remaining components to the structural model using co-evolution analysis of protein interfaces, to enable the reconstitution of the entire system including the pilus. This structure describes the exceptionally large protein–protein interaction network required to assemble the many components that constitute a T4SS and provides insights on the unique mechanism by which they elaborate pili.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 191-196
The conference challenges faced by scientists who stutter
Emily Sohn
Palabras clave: Multidisciplinary.
Pp. 197-199
Need web data? Here’s how to harvest them
Michael Eisenstein
Palabras clave: Multidisciplinary.
Pp. 200-201
Improving livestock to fight poverty and empower women
Nic Fleming
Palabras clave: Multidisciplinary.
Pp. 204-204