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Nature
Resumen/Descripción – provisto por la editorial en inglés
Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.Palabras clave – provistas por la editorial
No disponibles.
Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde jul. 2012 / hasta dic. 2023 | Nature.com | ||
| No detectada | desde jul. 2006 / hasta ago. 2012 | Ovid |
Información
Tipo de recurso:
revistas
ISSN impreso
0028-0836
ISSN electrónico
1476-4687
Editor responsable
Springer Nature
País de edición
Reino Unido
Fecha de publicación
1869-
Tabla de contenidos
How France ramped up its capacity to innovate
Nic Fleming
Palabras clave: Multidisciplinary.
Pp. No disponible
From the archive: transatlantic confusion, and a fascination with canals
Palabras clave: Multidisciplinary.
Pp. No disponible
Daily briefing: People who smell alike are more likely to ‘click’ as friends
Flora Graham
Palabras clave: Multidisciplinary.
Pp. No disponible
Cancer’s clock, data hoarding — the week in infographics
Palabras clave: Multidisciplinary.
Pp. No disponible
Daily briefing: First known case of getting COVID from a cat
Flora Graham
Palabras clave: Multidisciplinary.
Pp. No disponible
Ice Age wolf genomes home in on dog origins
Palabras clave: Multidisciplinary.
Pp. No disponible
Delta reinfection risk low among unvaccinated children
Heidi Ledford
Palabras clave: Multidisciplinary.
Pp. No disponible
Norovirus could spread through saliva: a new route for infection?
Benjamin Thompson; Nick Petrić Howe
Palabras clave: Multidisciplinary.
Pp. No disponible
Ouroboros
Thomas Broderick
Palabras clave: Multidisciplinary.
Pp. No disponible
Structures and mechanism of the plant PIN-FORMED auxin transporter
Kien Lam Ung; Mikael Winkler; Lukas Schulz; Martina Kolb; Dorina P. Janacek; Emil Dedic; David L. Stokes
; Ulrich Z. Hammes; Bjørn Panyella Pedersen
<jats:title>Abstract</jats:title><jats:p>Auxins are hormones that have central roles and control nearly all aspects of growth and development in plants<jats:sup>1–3</jats:sup>. The proteins in the PIN-FORMED (PIN) family (also known as the auxin efflux carrier family) are key participants in this process and control auxin export from the cytosol to the extracellular space<jats:sup>4–9</jats:sup>. Owing to a lack of structural and biochemical data, the molecular mechanism of PIN-mediated auxin transport is not understood. Here we present biophysical analysis together with three structures of <jats:italic>Arabidopsis thaliana</jats:italic> PIN8: two outward-facing conformations with and without auxin, and one inward-facing conformation bound to the herbicide naphthylphthalamic acid. The structure forms a homodimer, with each monomer divided into a transport and scaffold domain with a clearly defined auxin binding site. Next to the binding site, a proline–proline crossover is a pivot point for structural changes associated with transport, which we show to be independent of proton and ion gradients and probably driven by the negative charge of the auxin. The structures and biochemical data reveal an elevator-type transport mechanism reminiscent of bile acid/sodium symporters, bicarbonate/sodium symporters and sodium/proton antiporters. Our results provide a comprehensive molecular model for auxin recognition and transport by PINs, link and expand on a well-known conceptual framework for transport, and explain a central mechanism of polar auxin transport, a core feature of plant physiology, growth and development.</jats:p>
Palabras clave: Multidisciplinary.
Pp. No disponible