Catálogo de publicaciones - revistas

<jats:p>Periodic strong winds blowing opposite to the prevailing wind may explain the dune orientation on Titan.</jats:p>

<jats:p>Engineering functional lung tissue on the structural scaffold of the native organ in rodents points to a possible strategy for lung regeneration.</jats:p>

<jats:p>Biomass-derived sugars can be converted to fuels via conventional petrochemical processing.</jats:p>

<jats:p>The transformation of individual cold atoms between quantum phases has been imaged.</jats:p>

<jats:p>A collection of more than 2000 course syllabi, lecture notes, assignments, and exams is provided free of charge.</jats:p>

<jats:p> A monthly roundup of recent news and projects of <jats:italic>Science</jats:italic> 's publisher, the American Association for the Advancement of Science. </jats:p>

<jats:title>Insight into Silks</jats:title> <jats:p> Silkworms have been cultivated for thousands of years and their silk has been used to make fabrics for clothing, bed sheets, shirts, dresses, and for other applications like sutures. Spider silk is harder to harvest, and thus has not found such widespread use, but its fantastic combination of properties has made it a tempting material to study in detail. <jats:bold>Omenetto and Kaplan</jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" page="528" related-article-type="in-this-issue" vol="329" xlink:href="10.1126/science.1188936">528</jats:related-article> ) review our understanding of silk chemistry, the limitations in being able to reconstitute silks and to generate them synthetically, and a range of applications that have been developed using silk materials. </jats:p>

<jats:p>Highly impulsive individuals have diminished regulatory control of dopamine release.</jats:p>

<jats:title>Devil in the Detail</jats:title> <jats:p> Genetically identical cells in the same environment can show variation in gene expression that may cause phenotypic variation at the single-cell level. But how noisy are most genes? <jats:bold> Taniguchi <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" page="533" related-article-type="in-this-issue" vol="329" xlink:href="10.1126/science.1188308">533</jats:related-article> ; see the Perspective by <jats:bold> <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="5991" page="518" related-article-type="in-this-issue" vol="329" xlink:href="10.1126/science.1194036">Tyagi</jats:related-article> </jats:bold> ) now report single-cell global profiling of both messenger RNA (mRNA) and proteins in <jats:italic>Escherichia coli</jats:italic> using a yellow fluorescent protein fusion library. As well as a common extrinsic noise in high-abundance proteins, large fluctuations were observed in low-abundance proteins. Remarkably, in single-cell experiments, mRNA and protein levels for the same gene were uncorrelated. </jats:p>

<jats:title>Waiting to Exhale</jats:title> <jats:p> Lung tissue does not regenerate, so, when it is damaged by disease and/or surgically removed, lung transplantation is often the only treatment option. Because donor tissue is in short supply, there has been a long-standing interest in engineering functional and transplantable lung tissue in the laboratory. <jats:bold> Petersen <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" page="538" related-article-type="in-this-issue" vol="329" xlink:href="10.1126/science.1189345">538</jats:related-article> , published online 24 June; see the Perspective by <jats:bold> <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="5991" page="520" related-article-type="in-this-issue" vol="329" xlink:href="10.1126/science.1194087">Wagner and Griffith</jats:related-article> </jats:bold> ) now report an important step in this direction. After gently removing the cellular constituents of rat lungs with detergent, the residual scaffold of extracellular matrix—which retained the compliance and mechanical properties of the original lung—was re-seeded with a mixture of lung epithelial and endothelial cells and cultured in a bioreactor. Within a few days, the engineered lung tissue contained alveoli, microvessels, and small airways that were repopulated with the appropriate cell types. When transplanted into a rat for short time periods, the engineered lung showed evidence of gas exchange. </jats:p>