Catálogo de publicaciones - revistas
Multiple Sclerosis Journal
Resumen/Descripción – provisto por la editorial
No disponible.
Palabras clave – provistas por la editorial
No disponibles.
Disponibilidad
Institución detectada | Período | Navegá | Descargá | Solicitá |
---|---|---|---|---|
No detectada | desde feb. 1999 / hasta dic. 2023 | SAGE Journals |
Información
Tipo de recurso:
revistas
ISSN impreso
1352-4585
ISSN electrónico
1477-0970
Editor responsable
SAGE Publishing (SAGE)
País de edición
Estados Unidos
Fecha de publicación
1995-
Cobertura temática
Tabla de contenidos
Incidence and prevalence of neuromyelitis optica spectrum disorder in a contemporary, multi-ethnic cohort
Angus Lee; Radostina T Iordanova; Jessica B Smith; Bonnie H Li; Kathryn B Schwarzmann; Samir Alsalek; Talar S Habeshian; Sakar Budhathoki; Viridiana Hernandez-Lopez; Fernando Torres; Annette M Langer-Gould
<jats:sec> <jats:title>Background:</jats:title> <jats:p>Ecological comparisons suggest that neuromyelitis optic spectrum disorder (NMOSD) is more common in African Caribbean and Asian compared to White people.</jats:p> </jats:sec> <jats:sec> <jats:title>Objective:</jats:title> <jats:p>The aim is to rigorously assess susceptibility across multiple racial and ethnic groups from the same cohort.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods:</jats:title> <jats:p>We conducted a retrospective cohort study of > 39 million person-years of observation from members of Kaiser Permanente Southern California. The electronic health records of individuals with at least one International Classification of Diseases (ICD) code for NMOSD were reviewed to identify persons who met 2015 diagnostic criteria for NMOSD.</jats:p> </jats:sec> <jats:sec> <jats:title>Results:</jats:title> <jats:p>We identified 153 NMOSD cases, 105 incident and 105 prevalent. The age- and sex-standardized incidence (2013–2022) and prevalence (2019) according to the 2020 US Census per 100,000 person-years was significantly higher in Black persons (incidence = 0.90, 95% confidence interval (CI) = 0.59–1.21; prevalence = 8.44, 95% CI = 5.52–11.36) compared to all other racial and ethnic groups. The incidence was similar among Asian/Pacific Islander (0.32, 95% CI = 0.16–0.48) compared to Hispanic people (0.19, 95% CI = 0.13–0.25) and lowest in White people (incidence = 0.13, 95% CI = 0.07–0.19).</jats:p> </jats:sec> <jats:sec> <jats:title>Discussion:</jats:title> <jats:p>NMOSD susceptibility is highest in Black people, followed by Asian/Pacific Islands, then Hispanic people, and lowest in White people. Studies in diverse groups of minoritized people are needed to determine whether this increased susceptibility is due to shared genetic ancestry, the ill-health consequences of racism, or both.</jats:p> </jats:sec>
Pp. No disponible
Uncovering alternative diagnoses in patients with clinical syndromes suggestive of multiple sclerosis: A transversal study from the prospective Barcelona CIS cohort
Andreu Vilaseca
; Mar Tintoré
; Pere Carbonell-Mirabent; Marta Rodríguez-Barranco; Mª Jesús Arévalo
; Helena Ariño; Cristina Auger; Luca Bollo; René Carvajal; Joaquín Castilló; Alvaro Cobo-Calvo
; Manuel Comabella
; Victoria Fernández; Ingrid Galan; Luciana Midaglia; Neus Mongay-Ochoa; Carlos Nos; Susana Otero-Romero; Agustín Pappolla
; Jordi Rio
; Breogan Rodriguez-Acevedo
; Jaume Sastre-Garriga
; Sofía Sceppacuercia; Paula Tagliani
; Carmen Tur
; Angela Vidal-Jordana
; Javier Villacieros-Álvarez; Ana Zabalza
; Àlex Rovira
; Xavier Montalban; Georgina Arrambide
<jats:sec> <jats:title>Background:</jats:title> <jats:p>It is essential to exclude alternative diagnoses to diagnose multiple sclerosis (MS). However, detailed descriptions of alternative diagnoses in patients with suspected MS presenting with clinically isolated syndrome (CIS) are limited.</jats:p> </jats:sec> <jats:sec> <jats:title>Objectives:</jats:title> <jats:p>To describe alternative diagnoses in patients presenting with CIS suggestive of MS.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods:</jats:title> <jats:p>We conducted a descriptive analysis of patients from the Barcelona CIS cohort including subjects under 50 years of age with a CIS suggestive of MS but later diagnosed with conditions other than MS. We collected clinical, biological, and radiological data, and described the alternative etiologies identified.</jats:p> </jats:sec> <jats:sec> <jats:title>Results:</jats:title> <jats:p>Among 1468 patients in the Barcelona CIS cohort, 100 (6.8%) were diagnosed with an alternative condition. The most common neurological syndrome was optic neuritis (43.0%). Four patients (4.0%) had inflammatory-demyelinating lesions in at least two typical MS topographies on baseline magnetic resonance imaging (MRI), and 2 (2.0%) met the 2017 McDonald MS criteria. The most common etiologies were immune-mediated diseases (42.0%), especially MOGAD, followed by functional neurological disorders (15.0%) and vascular disease (10.0%).</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusion:</jats:title> <jats:p>The range of alternative diagnoses encountered during the MS diagnostic process highlights the need to rule out better explanations than MS. However, current MS diagnostic criteria effectively identify patients without MS in this context.</jats:p> </jats:sec>
Pp. 408-417