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Penile malignancies are uncommon in most parts of the world, but there is a striking geographical variation around the world. While the age-adjusted incidence rate is less than 1 per 100,000 in Europe and North America, in parts of South America, Africa, and India, the incidence is as high as 12 per 100,000 men []. Even within a country, there are marked regional variations. In Brazil the incidence of penile cancer is as high as 28 and 50 per 100,000 men in the cities of Sao Paulo and Recife, respectively []. Within Africa, the highest incidence has been reported from Uganda, where it is the most common cancer in males []. In India the disease is more common in the rural population with an incidence of 3 per 100,000 people accounting for more than 6% of all cancers in rural men [].