Catálogo de publicaciones - libros

Surgical anatomy and practical tips Surgical pathology Clinical presentation Methods of diagnosis and staging Surgical treatment of benign tumors Surgical treatment of malignant tumors Postoperative complications Indications for radiation treatment Perspectives

Pathology of metastatic cancer to the parotid Investigation and staging of cancer metastatic to the parotid Surgery for cancer metastatic to the parotid Adjuvant therapy for cancer metastatic to the parotid

Anatomic relationship between the parotid gland and the temporal bone Clinical signs suggestive of a temporal bone malignancy The usefulness of diagnostic testing The staging of temporal bone malignancies Indications and techniques for temporal bone resection The utility of neoadjuvant and adjuvant therapy

Implications of facial nerve damage on related central and peripheral structures Time schedule for facial nerve repair Decision criteria for facial nerve reconstruction Importance of normal function of the trigeminal nerve in cases of hypoglossal-facial reanimation (basic functional triad between Vth, VIIth, and XIIth cranial nerves) Disadvantages of cross-face anastomosis

Discussion of risk factors for metastasis from cancer of the salivary glands Algorithm for management of the clinically negative (N0) neck in cancer of the salivary glands based upon clinical assessment, fine-needle aspiration biopsy, and frozen section pathology Management of the clinically positive (N+) neck, including neck dissection and postoperative radiation therapy Future directions in understanding salivary gland tumorigenesis and cervical metastasis, such as using molecular markers for prognosis and developing targeted therapy

When tumors extend beyond the confines of the salivary gland (i.e., involving the skin, soft tissues, mandible, and/or facial nerve), reconstruction will likely be needed to restore the structure and function of the composite defect. A critical analysis of the defect (i.e., what structures are missing) and of the functional consequences will guide the most appropriate reconstruction. Two of the relatively minor sequelae of a parotidectomy that may be alleviated with reconstruction are Frey’s syndrome and the concavity at the site of the parotidectomy. An ideal option for reconstructing cutaneous defects after radical resection of a tumor of the parotid or submandibular gland is the use of cervicofacial or cervicodeltopectoral flaps. Free flaps are the ideal reconstructive technique in the reconstruction of parotidectomy and submandibular defects with extensive skin loss and involvement of the mandible. Procedures for facial reanimation at the time of parotidectomy are presented.

Discussion of the role of adjuvant radiotherapy in the treatment of salivary gland tumors Definitive conventional radiotherapy for the treatment of salivary gland tumors The unique role of neutron radiotherapy in the treatment of salivary gland tumors The role of radiotherapy in the treatment of pleomorphic adenomas

There are insufficient data to support the routine use of adjuvant or neoadjuvant chemotherapy. Chemotherapy should be reserved for the palliation of disease-related symptoms and for patients at risk of developing such symptoms due to rapid progression of locally recurrent or metastatic disease. In patients with indolent disease and without symptoms, watchful waiting is acceptable, and may be the preferred approach. The different histological subtypes of malignant tumors of salivary gland origin may have differing responsiveness to chemotherapeutic agents. The published literature on the role of systemic therapy in malignancies of the salivary glands is inadequate and limits the generation of evidence-based recommendations. All patients should be considered for participation in clinical trials to help define the role of systemic therapies in these tumors. As the understanding of the underlying molecular abnormalities of these tumors grows, there will be opportunities for the development and testing of novel, targeted agents.

Current definitions of quality of life (QOL) QOL instruments and challenges in QOL evaluation and measurement Effects, sequelae, and complications of salivary gland surgery Influence of the above on QOL Effects of surgery on salivary flow The changing approach with use of sialoendoscopy Advantages of cosmetically oriented incision lines