Catálogo de publicaciones - libros
Neuropsychiatric Disorders An Integrative Approach
M. Gerlach ; Jürgen Deckert ; K. Double ; E. Koutsilieri (eds.)
Resumen/Descripción – provisto por la editorial
No disponible.
Palabras clave – provistas por la editorial
Neurology; Clinical Psychology
Disponibilidad
| Institución detectada | Año de publicación | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | 2007 | SpringerLink |
Información
Tipo de recurso:
libros
ISBN impreso
978-3-211-73573-2
ISBN electrónico
978-3-211-73574-9
Editor responsable
Springer Nature
País de edición
Reino Unido
Fecha de publicación
2007
Información sobre derechos de publicación
© Springer-Verlag/Wien 2007
Cobertura temática
Tabla de contenidos
Neural stem cell transplantation in a model of fetal alcohol effects
T. Yoshinaga; E. Hashimoto; W. Ukai; S. Toki; S. Saito; T. Saito
Neural stem cell (NSC) transplantation has been investigated and developed in areas such as brain injury, stroke and neurodegenerative diseases. Recently, emerging evidence suggest that many of clinical symptoms observed in psychiatric disease are likely related to neural network disruptions including neurogenesis dysfunction. In the present study, we transplanted NSCs into a model of fetal alcohol effects (FAE) for the purpose of investigating the possibility of regenerative therapy for FAE. We labeled NSCs with fluorescent dye and radioisotope which were transplanted into FAE rats by intravenous injection. The transplanted cells were detected in wide areas of brain and were greater in number in the brains of the FAE group compared to the control group. Furthermore NSC transplantation attenuated behavioral abnormalities in FAE animals. These results suggest NSC transplantation as a potential new therapy for human FAE. Keywords
Palabras clave: Fetal alcohol effects; neural stem cell; transplantation; ethanol; fetal alcohol syndrome.
Pp. 331-337